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JACC:经导管肺动脉瓣置换术后的心内膜炎

2018-11-27 MedSci MedSci原创

心内膜炎已逐渐成为先天性右室流出道疾病和假体瓣膜疾病的主要不良并发症之一。本研究的目的旨在评估肺动脉瓣置换术后心内膜炎的发生率和潜在危险因素。本研究纳入分析了309例接受经导管肺动脉瓣置换术(TPVR)的患者,经过平均5.1年时间的随访,有46例患者被诊断为心内膜炎,有35例患者报道有肺动脉瓣置换相关性心内膜炎,心内膜炎的年度化发病率为3.1%每人年,而肺动脉瓣置换相关性心内膜炎为2.4%每人年。

心内膜炎已逐渐成为先天性右室流出道疾病和假体瓣膜疾病的主要不良并发症之一。本研究的目的旨在评估肺动脉瓣置换术后心内膜炎的发生率和潜在危险因素。

本研究纳入分析了309例接受经导管肺动脉瓣置换术(TPVR)的患者,经过平均5.1年时间的随访,有46例患者被诊断为心内膜炎,有35例患者报道有肺动脉瓣置换相关性心内膜炎,心内膜炎的年度化发病率为3.1%每人年,而肺动脉瓣置换相关性心内膜炎为2.4%每人年。多变量分析后发现,手术年龄≤12岁(HR:2.3; 95% Cl: 1.2 - 4.4; p = 0.011)和术后即刻压差≥15 mm Hg(HR:2.7; 95% Cl: 1.4 - 4.9; p = 0.002)与心内膜炎的发生相关。

研究结果显示,心内膜炎是先天性右室流出道疾病术后常见的不良并发症之一,应在预防和治疗上引起足够的重视。

原始出处:

Doff B et al.Endocarditis After Transcatheter Pulmonary Valve Replacement.JACC.2018 Dec.


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    2019-09-20 hbwxf
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    2019-10-19 yxch48
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