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Spine:症状性腰椎退变性骨关节炎在中国成人约8.9%

2014-09-09 orthowhq 丁香园

腰椎骨关节炎包块引起退变的一系列疾病,其带来的腰痛常可致残,误工,因而成为严重的负担。传统治疗方法包括保守和手术。腰椎骨关节炎发生率因国家不同而异。如英国发生率高于日本。中国的腰椎骨关节炎高发,尤其是西部。而且,随年龄而加重。 根据第六次人口普查的数据,北京已成为老龄社会,作为中国最发达的城市之一,北京近年来发展迅猛,然而,北京人口中腰椎骨关节炎的现状,尚不明确。 北京积水潭医院骨

腰椎骨关节炎包块引起退变的一系列疾病,其带来的腰痛常可致残,误工,因而成为严重的负担。传统治疗方法包括保守和手术。腰椎骨关节炎发生率因国家不同而异。如英国发生率高于日本。中国的腰椎骨关节炎高发,尤其是西部。而且,随年龄而加重。

根据第六次人口普查的数据,北京已成为老龄社会,作为中国最发达的城市之一,北京近年来发展迅猛,然而,北京人口中腰椎骨关节炎的现状,尚不明确。

北京积水潭医院骨科的学者进行了一项基于人口的研究,提示症状性腰椎退变性骨关节炎在中国成人中高发,发生率8.9%,文章于2014年8月发表在Spine上。

该研究基于不同社区、分阶段取样,共纳入18岁以上、在北京居住半年以上的3859个成人。腰椎骨关节炎的诊断包括临床症状(腰痛和麻木),体格检查和影像学检查(X线、CT、MRI)。

个人信息通过当面问讯得到,包括居住地,年龄,性别,收入,医保类型,教育水平,体重指数,吸烟和饮酒嗜好,工作类型,工作姿势,每天同一姿势工作时间,交通工具,震动与否,睡眠时间。计算初步和修正后发病率。以多变量回归方法分析人群及亚人群特征。

研究结果显示,腰椎骨关节炎的初步发病率为9.02%,修正后发病率为8.90%。城市、郊区和农村人口中发病率无明显差异(分别为7.66%,9.97%和9.44%)。成人女性发病率高于男性(10.05% 对 9.1%),随年龄而发生率递增。

肥胖者(体重指数大于28Kg/m2)、体力劳动者、每天同一姿势工作1-1.9小时者、每天工作中震动者、每天睡眠时间低于7小时者,腰椎骨关节炎发生率高。不同人群中这些特征不同。

上述研究结果为成人腰椎骨关节炎制定了流行病学基准数据,尤其是45岁以下成人。腰椎骨关节炎在北京高发,将成为老龄化社会的严重问题。不同的人群,腰椎骨关节炎的特征不同,而需特定的干预。

本研究中,腰椎骨关节炎的发病率与慢性阻塞性肺病(8.2%)和糖尿病的发病率(9.7%)类似,表明在北京比较普遍。腰椎骨关节炎在中国不同城市,发病率报道不同。不同研究报道的不同,主要在于腰椎骨关节炎定义的不同。

本研究中只纳入了腰痛退变所致骨关节炎,而且将40岁以下成人纳入并发现该人群中可观的发病率。本研究确定的腰椎骨关节炎的危险因素,均可用于腰椎骨关节炎的干预措施。

本研究中的病例只包含了有症状的腰椎骨关节炎者,有腰椎退变而无临床症状者可能被忽略,从而低估了腰椎骨关节炎的发病率。

原始出处:

Tian W1, Lv Y, Liu Y, Xiao B, Han X.The high prevalence of symptomatic degenerative lumbar osteoarthritis in Chinese adults: a population-based study.Spine (Phila Pa 1976). 2014 Jul 15;39(16):1301-10. doi: 10.1097/BRS.0000000000000396.

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    2015-08-10 lisa438
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    2015-08-15 mgqwxj
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    2014-09-11 lmm397
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    2014-09-11 huangdf
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