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Arthritis Care Res (Hoboken):短期有氧运动可缓解大多数类风湿患者疲劳

2015-01-30 MedSci MedSci原创

目的:目前类风湿性关节炎患者的疲劳没有很好的管理和有效的干预措施。有氧运动可能有利于治疗RA的疲劳。因此,此项meta分析的目的是探究有氧运动在RA的疲劳中的影响。 方法:利用Pubmed, Cochrane library, Embase和通过相关的试验注册,搜索随机对照试验的检索方法收纳相关实验研究,这些研究中陆地有氧运动按最大心率的50- 90%强度进行训练,至少连续进行4周,每周2次锻炼

目的:目前类风湿性关节炎患者的疲劳没有很好的管理和有效的干预措施。有氧运动可能有利于治疗RA的疲劳。因此,此项meta分析的目的是探究有氧运动在RA的疲劳中的影响。

方法:利用Pubmed, Cochrane library, Embase和通过相关的试验注册,搜索随机对照试验的检索方法收纳相关实验研究,这些研究中陆地有氧运动按最大心率的50- 90%强度进行训练,至少连续进行4周,每周2次锻炼,每次锻炼时间不少于15分钟。使用Cochrane工具进行偏倚风险评估。meta分析的结果是使用随机效应模型计算出的标准平均差(SMD)。

结果:5项随机对照试验被收纳。在这5项研究中患有类风湿性关节炎患者没有发生劳累。在3项研究中偏移风险很低,其他2项研究中不清楚。陆地有氧运动训练对类风湿性关节炎疲劳患者和没有进行有氧运动的患者相比在12周内有积极的影响,SMD (95%CI) =-0.31 (-0.55, -0.06)。在24周内,陆地有氧运动训练对对类风湿性关节炎患者疲劳的影响度降低甚至是没有意义,SMD -0.15 (-0.33, 0.02)。

结论:基于以上研究,我们得出在短时间内的有氧运动可以缓解大多数类风湿性关节炎患者的疲劳,相反,长时间的有氧运动效果较小。为了进一步证实这些实验结果,应该选择患有劳累性类风湿性关节炎患者进行研究

原始出处

Rongen-van Dartel SA1, Repping-Wuts H, Flendrie M, Bleijenberg G, Metsios GS, van den Hout WB, van den Ende CH, Neuberger G, Reid A, van Riel PL, Fransen J.The effect of aerobic exercise training on fatigue in rheumatoid arthritis: a meta-analysis.Arthritis Care Res (Hoboken). 2015 Jan 26.

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1972342, encodeId=a32819e2342af, content=<a href='/topic/show?id=8a6a2e8839' target=_blank style='color:#2F92EE;'>#Arthritis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2788, encryptionId=8a6a2e8839, topicName=Arthritis)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Mon Oct 26 01:40:00 CST 2015, time=2015-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260807, encodeId=5bdd126080ed2, content=<a href='/topic/show?id=493ee0559a7' target=_blank style='color:#2F92EE;'>#疲劳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70559, encryptionId=493ee0559a7, topicName=疲劳)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=674961, createdName=tamgche, createdTime=Sun Feb 01 08:40:00 CST 2015, time=2015-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1333770, encodeId=006d1333e706f, content=<a href='/topic/show?id=5306e6164b6' target=_blank style='color:#2F92EE;'>#类风湿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76164, encryptionId=5306e6164b6, topicName=类风湿)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Sun Feb 01 08:40:00 CST 2015, time=2015-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355962, encodeId=d061135596257, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Sun Feb 01 08:40:00 CST 2015, time=2015-02-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14921, encodeId=bb6314921d2, content=这个研究值得商榷, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=110.87.153.**, createdTime=Sat Jan 31 13:59:00 CST 2015, time=2015-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14875, encodeId=4a47148e555, content=纳入研究太少, beContent=null, objectType=article, channel=null, level=null, likeNumber=126, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Fri Jan 30 19:22:00 CST 2015, time=2015-01-30, status=1, ipAttribution=)]
    2015-02-01 tamgche
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    2015-02-01 zhaojie88
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    2015-01-31 110.87.153.**

    这个研究值得商榷

    0

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    2015-01-30 lovetcm

    纳入研究太少

    0

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