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JAMA Intern Med:随着机械通气的使用增加,老年痴呆症患者的生存并没有得到实质性益处

2016-10-12 MedSci MedSci原创

关键时刻,机械通气可是救命的招儿;但是对于某些老年痴呆症患者,机械通气肯定会增加患者的痛苦,且不一定会让患者的生存获益。 本项回顾性队列研究的研究对象为住院前120天居住在疗养院的晚期痴呆症患者,旨在描述使用机械通气的结局,以及机械通气与重症监护病房(ICU)床位增加之间的联系。 从2000年到2013年,共有380 060名符合条件的患者(30.5%为男性,平均[SD]年龄,84.4

关键时刻,机械通气可是救命的招儿;但是对于某些老年痴呆症患者,机械通气肯定会增加患者的痛苦,且不一定会让患者的生存获益。

本项回顾性队列研究的研究对象为住院前120天居住在疗养院的晚期痴呆症患者,旨在描述使用机械通气的结局,以及机械通气与重症监护病房(ICU)床位增加之间的联系。

从2000年到2013年,共有380 060名符合条件的患者(30.5%为男性,平均[SD]年龄,84.4 [ 7.4 ]岁)共发生了635 008次住院。

从2000年到2013年,机械通气的使用再增加,从39/1000住院到78/1000住院(P < .001,线性趋势检验)。随着时间的进展,ICU床位在增加,患有老年痴呆症的患者更可能接受机械通气(每增加10张ICU床位,校正后的OR值为1.06; 95% CI, 1.05-1.07)。

2013年,ICU的病床数在前10%的医院,其住院报销费用为$9611.89/住院;ICU的病床数在后10%的医院,其数据为$8050.24(P < .001);但是患者的1年死亡率并没有改善(65.2% vs 64.6%; P = 54)。

结果表明,随着ICU病床数的增加,机械通气的使用增加,但是对于老年痴呆症患者,随着机械通气的使用增加,患者的生存并没有得到显著改善。

原始出处:

Joan M. Teno,et al.Association of Increasing Use of Mechanical Ventilation Among Nursing Home Residents With Advanced Dementia and Intensive Care Unit Beds.JAMA Intern Med. Published online October 10, 2016

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    2017-03-09 Boyinsh
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    2016-10-22 1e0ece0dm09(暂无匿称)

    谢谢分享学习

    0

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    2016-10-19 cjingjuan

    中国ICU现状

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1836127, encodeId=5e0c183612ed2, content=<a href='/topic/show?id=4613e1212fc' target=_blank style='color:#2F92EE;'>#痴呆症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71212, encryptionId=4613e1212fc, topicName=痴呆症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Thu Mar 09 19:37:00 CST 2017, time=2017-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150292, encodeId=ac7a150292d1, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Oct 22 10:46:52 CST 2016, time=2016-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149688, encodeId=ac4014968859, content=中国ICU现状, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7c3865018, createdName=cjingjuan, createdTime=Wed Oct 19 09:29:43 CST 2016, time=2016-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148220, encodeId=8f79148220e1, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57ab1959292, createdName=boc_111, createdTime=Fri Oct 14 14:31:09 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148219, encodeId=922b148219a9, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57ab1959292, createdName=boc_111, createdTime=Fri Oct 14 14:30:54 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148218, encodeId=19af14821873, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57ab1959292, createdName=boc_111, createdTime=Fri Oct 14 14:30:40 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607146, encodeId=7d73160e14683, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Oct 14 02:37:00 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146751, encodeId=4bfd146e5141, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Oct 12 12:59:32 CST 2016, time=2016-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146749, encodeId=a646146e4950, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Oct 12 12:59:26 CST 2016, time=2016-10-12, status=1, ipAttribution=)]
    2016-10-14 boc_111

    谢谢分享学习了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1836127, encodeId=5e0c183612ed2, content=<a href='/topic/show?id=4613e1212fc' target=_blank style='color:#2F92EE;'>#痴呆症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71212, encryptionId=4613e1212fc, topicName=痴呆症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Thu Mar 09 19:37:00 CST 2017, time=2017-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150292, encodeId=ac7a150292d1, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Oct 22 10:46:52 CST 2016, time=2016-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149688, encodeId=ac4014968859, content=中国ICU现状, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7c3865018, createdName=cjingjuan, createdTime=Wed Oct 19 09:29:43 CST 2016, time=2016-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148220, encodeId=8f79148220e1, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57ab1959292, createdName=boc_111, createdTime=Fri Oct 14 14:31:09 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148219, encodeId=922b148219a9, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57ab1959292, createdName=boc_111, createdTime=Fri Oct 14 14:30:54 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148218, encodeId=19af14821873, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57ab1959292, createdName=boc_111, createdTime=Fri Oct 14 14:30:40 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607146, encodeId=7d73160e14683, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Oct 14 02:37:00 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146751, encodeId=4bfd146e5141, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Oct 12 12:59:32 CST 2016, time=2016-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146749, encodeId=a646146e4950, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Oct 12 12:59:26 CST 2016, time=2016-10-12, status=1, ipAttribution=)]
    2016-10-14 boc_111

    谢谢分享学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1836127, encodeId=5e0c183612ed2, content=<a href='/topic/show?id=4613e1212fc' target=_blank style='color:#2F92EE;'>#痴呆症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71212, encryptionId=4613e1212fc, topicName=痴呆症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=726030, createdName=Boyinsh, createdTime=Thu Mar 09 19:37:00 CST 2017, time=2017-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150292, encodeId=ac7a150292d1, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Sat Oct 22 10:46:52 CST 2016, time=2016-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149688, encodeId=ac4014968859, content=中国ICU现状, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7c3865018, createdName=cjingjuan, createdTime=Wed Oct 19 09:29:43 CST 2016, time=2016-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148220, encodeId=8f79148220e1, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57ab1959292, createdName=boc_111, createdTime=Fri Oct 14 14:31:09 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148219, encodeId=922b148219a9, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57ab1959292, createdName=boc_111, createdTime=Fri Oct 14 14:30:54 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148218, encodeId=19af14821873, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57ab1959292, createdName=boc_111, createdTime=Fri Oct 14 14:30:40 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607146, encodeId=7d73160e14683, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Fri Oct 14 02:37:00 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146751, encodeId=4bfd146e5141, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Oct 12 12:59:32 CST 2016, time=2016-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=146749, encodeId=a646146e4950, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed Oct 12 12:59:26 CST 2016, time=2016-10-12, status=1, ipAttribution=)]
    2016-10-14 boc_111

    谢谢分享学习了

    0

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    2016-10-12 doctorJiangchao

    继续关注

    0

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    2016-10-12 doctorJiangchao

    继续学习

    0

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