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Nutr J:炎性肠病患者饮食和营养研究

2016-08-30 Moon 译 MedSci原创

炎性肠病简称IBD,是一种特殊的慢性肠道炎症性疾病,主要包括克罗恩病(CD)和溃疡性结肠炎(UC)。炎症性肠病(IBD)可能与营养问题有关。本研究的目的是调查IBD患者的饮食和营养情况。 这项横断面研究研究共纳入了78名参与者(35名男性和43名女性,年龄18-74岁),大多数(80%)的参与者接受英夫利昔单抗治疗。所有参与者完成了疾病相关问卷调查,31名参与者还进行了为期3天的食物记录。研

炎性肠病简称IBD,是一种特殊的慢性肠道炎症性疾病,主要包括克罗恩病(CD)和溃疡性结肠炎(UC)。炎症性肠病(IBD)可能与营养问题有关。本研究的目的是调查IBD患者的饮食和营养情况。

这项横断面研究研究共纳入了78名参与者(35名男性和43名女性,年龄18-74岁),大多数(80%)的参与者接受英夫利昔单抗治疗。所有参与者完成了疾病相关问卷调查,31名参与者还进行了为期3天的食物记录。研究者通过测量身体成分和分析血液样本对参与者的估计营养进行状况。

数据显示,多数人(87%)声称饮食影响消化道症状,72 %的参与者相应地改变了饮食。最常见的受限食物是乳制品(60%)、加工肉类(55%)、软饮料(46%)、酒精(45%)和快餐(44%)。虽然参与者体重指数大多处于超重范围,但是仍有46%的参与者基于IBD被诊断出营养不良(最常见的是缺铁:39%)。肉类制品受限的患者有较低的铁蛋白值(48 ± 39 vs. 95 ± 74 μg/L, P = 0.011)。维生素D和钙的摄入也不足(低于推荐摄入量的65%),60%的参与者有较差的维生素D水平。

因为消化道症状,IBD患者经常改变他们的饮食,许多患者有营养缺乏的病史。受限的食物中乳制品和肉类是常见的,并且与营养素(如钙、铁)的摄入呈负相关。由营养师对IBD患者提出饮食建议,以及使用膳食补充剂可能对患者有益。

原始出处:


Vidarsdottir JB.et al.A cross-sectional study on nutrient intake and -status in inflammatory bowel disease patients.Nutr J. 2016 Jun 8;15(1):61. doi: 10.1186/s12937-016-0178-5.

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10:25:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2017-10-17 cscdliu

    学习了.谢谢

    0

  2. 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    2017-05-14 138****1711

    学习了,感谢分享

    0

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10:25:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-09-23 1e10c84am36(暂无匿称)

    文章不错,继续学习

    0

  4. 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GetPortalCommentsPageByObjectIdResponse(id=113415, encodeId=55ba113415ff, content=内容很好啊。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ceb079804, createdName=lhl629, createdTime=Thu Sep 08 05:27:00 CST 2016, time=2016-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=111952, encodeId=376a111952e4, content=继续努力,每天都有提高。, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ceb079804, createdName=lhl629, createdTime=Tue Sep 06 04:48:00 CST 2016, time=2016-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=111217, encodeId=87e011121ef6, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, 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encodeId=eee8109583d4, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:49:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108127, encodeId=f7be10812e74, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:25:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-09-13 lhl629

    继续努力。。。

    0

  5. 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encodeId=eee8109583d4, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:49:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108127, encodeId=f7be10812e74, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:25:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-09-08 lhl629

    内容很好啊。。。。

    0

  6. 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encodeId=eee8109583d4, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:49:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108127, encodeId=f7be10812e74, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:25:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-09-06 lhl629

    继续努力,每天都有提高。

    0

  7. 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encodeId=eee8109583d4, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:49:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108127, encodeId=f7be10812e74, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:25:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-09-05 李东泽

    很好,不错,以后会多学习

    0

  8. 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likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Mon Sep 05 10:09:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109584, encodeId=63bc109584a0, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:49:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109583, encodeId=eee8109583d4, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:49:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108127, encodeId=f7be10812e74, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:25:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-09-02 doctorJiangchao

    继续关注

    0

  9. 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likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Mon Sep 05 10:09:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109584, encodeId=63bc109584a0, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:49:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109583, encodeId=eee8109583d4, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:49:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108127, encodeId=f7be10812e74, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:25:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-09-02 doctorJiangchao

    继续学习

    0

  10. 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encodeId=eee8109583d4, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Fri Sep 02 11:49:00 CST 2016, time=2016-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108127, encodeId=f7be10812e74, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Aug 31 10:25:00 CST 2016, time=2016-08-31, status=1, ipAttribution=)]
    2016-08-31 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

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目前关于利用英夫利昔治疗来预测炎症性肠病患者粘膜愈合情况的确凿数据仍然匮乏,针对这种情况,来自法国圣艾蒂安免疫学与免疫监测实验室的Paul Stephane博士等人进行了一项研究,研究结果发表于2013年11月的《炎症性肠病》(Inflammatory Bowel Diseases)上。研究发现:英夫利昔的药物监测可有效地预测炎症性肠病患者的粘膜愈合情况。【原文下载】 研究对2010年6月-20

Gastroenterology :炎性肠病的手术风险随着时间推移已逐渐降低

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用抗肿瘤坏死因子(TNF)的抗体治疗的炎性肠病(IBD)患者亚组使皮肤发生病变,但病灶及其临床过程没有得到充分表征。该研究的目的是描述TNF抗体治疗有和没有出现皮肤损伤的患者特征。该回顾性队列研究在单IBD三级转诊中心进行,共有917例连续IBD患者开始接受抗TNF治疗。主要终点和措施为皮肤损害,患者的人口学特征,治疗方法,临床过程和血清学和基因标记。在平均随访3.5年规程中(四分位距[IQR],

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