JAHA：早产与产妇心血管疾病风险分析！

2018-01-15 xing.T MedSci原创

由此可见，早产与产妇未来心血管不良结局的增加有关，包括冠心病死亡增加2倍。这些发现支持了对早产妇女进行心血管风险评估。

早产（小于37周孕龄）约占所有妊娠的11%，但早产是否与心血管长期的不良结局之间相关性的数据是矛盾的。近日，心血管疾病领域权威杂志JAHA上发表了一篇荟萃分析文章，研究人员旨在系统地评估和总结早产与未来孕妇心血管疾病风险之间相关性的证据。

研究人员系统地检索了MEDLINE和EMBASE数据库，以确定评估早产和产妇心血管疾病、冠心病、卒中、以及由心血管或冠状动脉心脏病和卒中引起死亡的复合事件风险之间相关性的研究。研究人员使用随机效应荟萃分析量化这些相关性。

二十一项研究约包含了580万多名妇女，其中纳入了338000名既往有早产的妇女。调整了潜在混杂因素的Meta分析表明早产与产妇未来心血管疾病（风险比[RR]为1.43，95%可信区间[CI]为1.18-1.72）、心血管疾病死亡（RR为1.78，95%可信区间为1.42-2.21）、冠心病（RR为1.49，95%可信区间为1.38-1.60）、冠心病死亡（RR为2.10，95%可信区间为1.87-2.36）和卒中（RR为1.65，95%可信区间为1.51-1.79）风险增加相关。敏感性分析显示当早产发生在妊娠前32周或存在医学指征的产妇风险最高。

由此可见，早产与产妇未来心血管不良结局的增加有关，包括冠心病死亡增加2倍。这些发现支持了对早产妇女进行心血管风险评估。

原始出处：

Pensée Wu, et al. Preterm Delivery and Future Risk of Maternal Cardiovascular Disease: A Systematic Review and Meta‐Analysis.JAHA.2018. https://doi.org/10.1161/JAHA.117.007809

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2018-04-04 考拉2177

真的是方方面面都需要注意呀

99 0
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2018-01-31 方舒

学习

0 0
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2018-01-22 方舒

学习

83 0
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2018-01-19 大爰

学习了谢谢分享!!

79 0
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2018-01-17 zhaohui6731

#AHA#

63 0
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2018-01-17 花花1368

#疾病风险#

66 0
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2018-01-17 andy2090

#血管疾病#

48 0
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2018-01-16 15121100f4m

机制或者可能得机制是什么呢?

79 0
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2018-01-15 changjiu

学习一下谢谢

74 0

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