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Stroke:PM2.5可怕,短期暴露更可怕!

2016-11-12 xing.T MedSci原创

这些研究结果表明,短期暴露于PM2.5(1天内)与缺血性脑卒中的发生密切相关。

有研究已经证实空气中颗粒物(PM)的浓度和心血管疾病之间存在密切的关系。然而,目前尚不清楚是否短期暴露于细颗粒物(PM2.5)中是否会引发缺血性脑卒中事件,以及PM2.5暴露时间长短与脑卒中风险存在相关性。近日,卒中领域权威杂志Stroke上发表了一篇来自日本福冈九州大学卫生行政管理部门Ryu Matsuo博士及其团队的研究文章,旨在探究暴露于环境中可吸入肺颗粒物PM2.5时间长短与缺血性脑卒中发生的关系。

研究人员分析了日本多个以医院为基础的脑卒中注册中心的6885例缺血性脑卒中患者,这些患者均在发病24小时内入院接受治疗,而且脑卒中症状发作时间也是确定的,研究人员采用时间分层的病例交叉分析方法分析了PM(悬浮颗粒物和PM2.5)与缺血性脑卒中之间的关系。

研究者发现短期暴露于空气中PM2.5和悬浮颗粒物(滞留0天到1天)就与之后缺血性脑卒中的发生有关(对环境温度进行调整后的比值比[95%置信区间]:每10μg/m3的悬浮颗粒物的情况下为1.02[1.00–1.05];每10μg/m3的PM2.5的情况下为1.03 [1.00–1.06])。相比之下,空气中悬浮颗粒物和PM2.5滞留2天到3天或4天到6天显示与脑卒中的发生无明显相关性。通过对其他空气污染物(二氧化氮、光化学氧化剂或二氧化硫)或流感的流行这些混杂因素进行调整后,研究者发现空气中PM2.滞留0天到1天与缺血性脑卒中发生之间的相关性仍然存在,而且在寒冷季节它们之间这种相关性更加明显。

这些研究结果表明,短期暴露于PM2.5(1天内)与缺血性脑卒中的发生密切相关。

原始出处:

Ryu Matsuo,et al. Short-Term Exposure to Fine Particulate Matter and Risk of Ischemic Stroke. Stroke. 2016. 

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1800919, encodeId=0e111800919f3, content=<a href='/topic/show?id=4628e3208c7' target=_blank style='color:#2F92EE;'>#短期暴露#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73208, encryptionId=4628e3208c7, topicName=短期暴露)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=226a143, createdName=cathymary, createdTime=Tue Jan 24 18:25:00 CST 2017, time=2017-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=168348, encodeId=8b0f16834821, content=值得参考、借鉴, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Jan 06 13:04:24 CST 2017, time=2017-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157627, encodeId=e6d115e62713, content=能不能和进化联系?, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/651DB1E2868EC9DCC2604FF273E68010/100, createdBy=b4d61981770, createdName=KevinSong, createdTime=Wed Nov 23 14:21:17 CST 2016, time=2016-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155773, encodeId=ee1a155e7373, content=戴口罩还是很有必要的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5WdRCZb0Hs1YiaOB88m23a0oYulDm9Z0Es2N8rk8dmG1tkgXOibgBGBTMpwlof4aic6HdrIeR2zF09okwsgRbedK0/0, createdBy=72f41927023, createdName=Johnson_zhangdr, createdTime=Tue Nov 15 00:34:00 CST 2016, time=2016-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264963, encodeId=617b1264963c6, content=<a href='/topic/show?id=9574144034a' target=_blank style='color:#2F92EE;'>#PM2.5#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14403, encryptionId=9574144034a, topicName=PM2.5)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87f580, createdName=yilong5287542, createdTime=Mon Nov 14 00:25:00 CST 2016, time=2016-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155544, encodeId=8c08155544df, content=日本人为什么这么研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Sun Nov 13 23:30:24 CST 2016, time=2016-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155332, encodeId=8087155332d7, content=有这么明显的作用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19711706499, createdName=1de9282dm20(暂无匿称), createdTime=Sat Nov 12 23:07:05 CST 2016, time=2016-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155323, encodeId=b6c5155323fe, content=大天朝的老百姓怎么办?, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2dd71722896, createdName=studylzc, createdTime=Sat Nov 12 22:00:08 CST 2016, time=2016-11-12, status=1, ipAttribution=)]
    2017-01-06 虈亣靌

    值得参考、借鉴

    0

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    2016-11-23 KevinSong

    能不能和进化联系?

    0

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    2016-11-15 Johnson_zhangdr

    戴口罩还是很有必要的。

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1800919, encodeId=0e111800919f3, content=<a href='/topic/show?id=4628e3208c7' target=_blank style='color:#2F92EE;'>#短期暴露#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73208, encryptionId=4628e3208c7, topicName=短期暴露)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=226a143, createdName=cathymary, createdTime=Tue Jan 24 18:25:00 CST 2017, time=2017-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=168348, encodeId=8b0f16834821, content=值得参考、借鉴, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Jan 06 13:04:24 CST 2017, time=2017-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=157627, encodeId=e6d115e62713, content=能不能和进化联系?, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/651DB1E2868EC9DCC2604FF273E68010/100, createdBy=b4d61981770, createdName=KevinSong, createdTime=Wed Nov 23 14:21:17 CST 2016, time=2016-11-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155773, encodeId=ee1a155e7373, content=戴口罩还是很有必要的。, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5WdRCZb0Hs1YiaOB88m23a0oYulDm9Z0Es2N8rk8dmG1tkgXOibgBGBTMpwlof4aic6HdrIeR2zF09okwsgRbedK0/0, createdBy=72f41927023, createdName=Johnson_zhangdr, createdTime=Tue Nov 15 00:34:00 CST 2016, time=2016-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264963, encodeId=617b1264963c6, content=<a href='/topic/show?id=9574144034a' target=_blank style='color:#2F92EE;'>#PM2.5#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14403, encryptionId=9574144034a, topicName=PM2.5)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=87f580, createdName=yilong5287542, createdTime=Mon Nov 14 00:25:00 CST 2016, time=2016-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155544, encodeId=8c08155544df, content=日本人为什么这么研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151226/IMG567EB873985DE3928.jpg, createdBy=ea941622301, createdName=inter158, createdTime=Sun Nov 13 23:30:24 CST 2016, time=2016-11-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155332, encodeId=8087155332d7, content=有这么明显的作用?, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19711706499, createdName=1de9282dm20(暂无匿称), createdTime=Sat Nov 12 23:07:05 CST 2016, time=2016-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=155323, encodeId=b6c5155323fe, content=大天朝的老百姓怎么办?, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2dd71722896, createdName=studylzc, createdTime=Sat Nov 12 22:00:08 CST 2016, time=2016-11-12, status=1, ipAttribution=)]
    2016-11-13 inter158

    日本人为什么这么研究

    0

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    2016-11-12 1de9282dm20(暂无匿称)

    有这么明显的作用?

    0

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    2016-11-12 studylzc

    大天朝的老百姓怎么办?

    0

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