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ACC2011:迷走神经节消融治疗长期持续性房颤

2011-05-07 MedSci原创 MedSci原创

     背景:迷走神经节消融(GP)对长期持续性房颤患者的治疗效果仍未明确。     方法:89名有症状、药物治疗无效的持续性房颤患者接受左心房迷走神经节区域的解剖消融(男性71名;年龄56±7)。之后29名患者接受环肺静脉隔离术的二次消融,其中5名患者进行第三次CPVI。  &nbsp

     背景:迷走神经节消融(GP)对长期持续性房颤患者的治疗效果仍未明确。
     方法:89名有症状、药物治疗无效的持续性房颤患者接受左心房迷走神经节区域的解剖消融(男性71名;年龄56±7)。之后29名患者接受环肺静脉隔离术的二次消融,其中5名患者进行第三次CPVI。
     结果:末次消融后随访16±7个月,53(59.8%)名患者在未服用抗心律失常药物治疗的情况下恢复窦性心律,5 (5.6%)名患者诊断为永久性房颤,31 (34.8%)名患者诊断为阵发性房颤。随访超过24±3个月后,仅接受GP单次消融的患者长期成功率为38.2%。左心房直径[HR 1.039 (1.00-1.07), P = 0.028]和术前房颤持续时间[HR 1.116 (1.02-1.22), P = 0.008]为远期心律失常复发的独立预测因素。
     结论:38.2%的慢性房颤患者接受GP消融后能长期维持窦性节律。随访16±7个月,采用CPVI进行再次消融的成功率为59.6%。

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    2015-09-27 mahadev

    Wonderful expnolatian of facts available here.

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