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Diabetic Med:日本儿童期1型糖尿病的发病率和患病率如何?

2017-06-22 MedSci MedSci原创

近日,国际杂志《Diabetic Medicine》在线发表了一项关于日本儿童期1型糖尿病的发病率和患病率的T1D研究。在政府资助的特殊儿科慢性疾病治疗研究项目(SPCDTRP)中,日本大多数1型糖尿病儿童注册在其中。 在本研究中,通过利用SPCDTRP数据估计日本儿童期(<15岁)1型糖尿病的发病率和患病率。

近日,国际杂志《Diabetic Medicine》在线发表了一项关于日本儿童1糖尿病的发病率和患病率的T1D研究。在政府资助的特殊儿科慢性疾病治疗研究项目(SPCDTRP)中,日本大多数1糖尿病儿童注册在其中。 在本研究中,通过利用SPCDTRP数据估计日本儿童期(<15岁)1糖尿病的发病率和患病率。

使用来自内政和交通部SPCDTRP和统计局2005-2012的数据估计2005 - 20101型糖尿病的发病率,校正为覆盖发病3年内登记并按性别、发病年龄和发病期分层的患者。

2005 - 20101型糖尿病发病率为2.25 / 100,000[95CI2.14-2.36](男孩:1.9195CI1.83-1.98;女孩:2.52,95CI2.34-2.69),其中0-4,5-910-14岁年龄发病率分别为1.4895CI1.29-1.66),2.2795CI2.08-2.47)和3.0095 CI2.74-3.25)。 男孩在13岁时出现疾病发病率高峰(3.28,95CI3.02-3.55),女孩10岁时出现高峰(3.28,95CI3.02-3.55)。 发病高峰期为每年的四月/五月和十二月。 2005 - 2012年度15岁以下儿童患1型糖尿病人数估计为2326人(95CI2202-2450人),患病率估计为13.53 / 10万人(95CI12.63-14.43)。

研究结果表明,尽管与早期报道一致但是女性青春期发病高峰较早,但1型糖尿病的发病率没有增加,另外,儿童早发性糖尿病的发病率表现为年度双峰模式。

原始出处:

Y. Onda, S. Sugihara, T. Ogataet al. Incidence and prevalence of childhood-onset Type 1 diabetes in Japan: the T1D study. (pages 909915)

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