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Sci Rep:过敏性鼻炎和中耳炎相关性分析

2019-02-25 AlexYang MedSci原创

尽管许多研究报道了儿童中,过敏性鼻炎是一个独立的风险因子并与中耳炎高度相关,然而,仍旧缺乏关于人口统计学的流行病学研究。最近,有研究人员在韩国当地人口中,使用全国的调查数据鉴定了是否在年龄为7-12岁的儿童中,过敏性鼻炎是中耳炎的独立风险因子。研究包括了472名儿童(248名男性和224名女性),他们在2015年完成了韩国国家健康与营养调查。中耳炎由耳鼻喉科专家使用鼓室测量、听力测量和耳镜检查来鉴

尽管许多研究报道了儿童中,过敏性鼻炎是一个独立的风险因子并与中耳炎高度相关,然而,仍旧缺乏关于人口统计学的流行病学研究。最近,有研究人员在韩国当地人口中,使用全国的调查数据鉴定了是否在年龄为7-12岁的儿童中,过敏性鼻炎是中耳炎的独立风险因子。

研究包括了472名儿童(248名男性和224名女性),他们在2015年完成了韩国国家健康与营养调查。中耳炎由耳鼻喉科专家使用鼓室测量、听力测量和耳镜检查来鉴定。过敏性鼻炎通过儿童哮喘与过敏国际研究韩国版本来进行诊断,具体包括了总血清免疫球蛋白E测试、过敏原特异性免疫球蛋白测试、血液嗜酸粒细胞测试和嗜酸性粒细胞阳离子蛋白检测,嗜酸性粒细胞鼻腔细胞学检测,皮肤反应检测和抗原同时检测。混杂因素包括了年龄、性别、家庭收入水平和家庭构成,并利用一个复杂样本逻辑回归分析对过敏性鼻炎和中耳炎的关系进行了分析,并确定了95%置信区间。研究发现,儿童中过敏性鼻炎与中耳炎显著相关(p<0.05)。在调整了所有混杂因素后,患有过敏性鼻炎的儿童具有是不患有过敏性鼻炎儿童2倍的中耳炎风险(OR=2.04; 95% CI: 1.30-3.18)。

最后,研究人员指出,他们的流行病学研究确定了儿童过敏性鼻炎和中耳炎的独立关系。在未来,纵向的研究需要进一步确定过敏性鼻炎与中耳炎之间的因果关系。

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