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NEJM:橄榄球运动员的神经退行性疾病死亡风险增加

2019-10-22 MedSci MedSci原创

在这项回顾性流行病学分析中,前苏格兰职业橄榄球运动员的神经退行性疾病死亡率高于对照组,其他常见疾病死亡率低于对照组

统计证实,强对抗运动员罹患神经退行性疾病风险增加。近日研究人员就前职业橄榄球运动员神经退行性疾病的发病特点进行了考察。

本次研究为一项回顾性队列研究,比较7676名前职业橄榄球运动员与23028名匹配普通对照者的神经退行性疾病死亡率。

18岁年间,1180名前运动员(15.4%)和3807名对照组(16.5%)死亡。在70岁以前,前运动员的全因死亡率低于对照组,但此后升高。前运动员的缺血性心脏病死亡率低于对照组(HR:0.80),肺癌死亡率也低于对照组(HR:0.53)。运动员神经退行性疾病的死亡率为1.7%,在对照组中为0.5%。(3.45),其中阿尔茨海默病发病率最高(5.07)而帕金森病发病率最低(HR:2.15)。与对照组相比,运动员老年痴呆症相关的药物治疗更频繁(OR:4.90)。

在这项回顾性流行病学分析中,前苏格兰职业橄榄球运动员的神经退行性疾病死亡率高于对照组,其他常见疾病死亡率低于对照组。

原始出处:

Daniel F. Mackay et al. Neurodegenerative Disease Mortality among Former Professional Soccer Players. N Engl J Med, October 21, 2019.

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    2019-10-24 gujh
  5. [GetPortalCommentsPageByObjectIdResponse(id=1957173, encodeId=ca88195e17347, content=<a href='/topic/show?id=5879e458629' target=_blank style='color:#2F92EE;'>#神经退行#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74586, encryptionId=5879e458629, topicName=神经退行)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=33b92500139, createdName=12498b37m72暂无昵称, createdTime=Thu Apr 30 00:23:00 CST 2020, time=2020-04-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1735396, encodeId=dfb91e353965a, content=<a href='/topic/show?id=740394686b2' target=_blank style='color:#2F92EE;'>#退行性疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94686, encryptionId=740394686b2, topicName=退行性疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Sun Dec 08 12:23:00 CST 2019, time=2019-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255912, encodeId=8a6a1255912fd, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Thu Oct 24 09:23:00 CST 2019, time=2019-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1604596, encodeId=0665160459649, content=<a href='/topic/show?id=88e6941544c' target=_blank style='color:#2F92EE;'>#运动员#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94154, encryptionId=88e6941544c, topicName=运动员)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0c1419230799, createdName=gujh, createdTime=Thu Oct 24 09:23:00 CST 2019, time=2019-10-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1034993, encodeId=4985103499380, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Tue Oct 22 21:23:00 CST 2019, time=2019-10-22, status=1, ipAttribution=)]
    2019-10-22 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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