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Laryngoscope:lgE的早期反应能够预测舌下免疫治疗的满意度

2020-07-13 ALexYang MedSci原创

最近,有研究人员在过敏性鼻炎患者中进行了一个回顾性的队列研究,调查了基线时间点和屋尘螨舌下免疫治疗(SLIT)早期响应期间的预测参数。

最近,有研究人员在过敏性鼻炎患者中进行了一个回顾性的队列研究,调查了基线时间点和屋尘螨舌下免疫治疗(SLIT)早期响应期间的预测参数。

患者接受SLIT治疗至少3年,并在基线时间点和随访1年后进行血清学检测来调查预测参数。在SLIT治疗第3年,研究人员评估了对SLIT的满意度、4种鼻部症状和生活质量。研究共包括了61名患者,并根据他们对SLIT 3年后的满意度分为两组:43人满意(70.5%),18人不满意(29.5%)。研究发现,在治疗满意组和不满意组之间,基线时间点的免疫学参数没有显著差异。然而,在早期SLIT响应期间,屋尘螨(Dp)和粉尘螨特异性lgEs在不满意组中要比满意组显著更高(P=0.006和P=0.045)。

最后,研究人员指出,Dp-和Df-特异性lgE水平在早期响应中的变化是SLIT长期治疗结果的一个指示因子。临床医生可以在SLIT治疗后1年来测量这些免疫参数,从而判断响应的有无。

原始出处:

Jin Youp Kim , Chae-Seo Rhee , Sue Jean Munet al. Early Response of Specific IgE Can Predict Satisfaction With Sublingual Immunotherapy. Laryngoscope. 20 June 2020.

 

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    2020-08-08 feather89
  2. [GetPortalCommentsPageByObjectIdResponse(id=1728598, encodeId=760b1e28598a0, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Aug 08 06:09:43 CST 2020, time=2020-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802858, encodeId=28ef80285859, content=好方法, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=83185307473, createdName=1487d582m08暂无昵称, createdTime=Wed Jul 15 12:55:18 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802837, encodeId=02f880283eb3, content=积分, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLJv7sDRP4SAgnKpriaexAiaLUgTpa8f4G8RcbH2ia1pRjHODZWtIJBPW7BctUSCC64odNklA6iaboiapQ/132, createdBy=797d2509270, createdName=小惠, createdTime=Wed Jul 15 09:01:31 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802824, encodeId=d9138028242b, content=非常感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eof7QgiaM40Cbk9nEupXmSOY1ibC6icYDYgtF7MMZoDnic7g0cyKqthJ2NLxE1WSiaib43H9DE4iaNQPFUBg/132, createdBy=9f9f5279032, createdName=李继鹏, createdTime=Wed Jul 15 07:13:48 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478697, encodeId=a58914e86976f, content=<a href='/topic/show?id=d561665e7af' target=_blank style='color:#2F92EE;'>#满意度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66577, encryptionId=d561665e7af, topicName=满意度)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1627448984, createdName=ms1692212821629096, createdTime=Wed Jul 15 04:09:43 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1539234, encodeId=54841539234c3, content=<a href='/topic/show?id=6505108534a' target=_blank style='color:#2F92EE;'>#lgE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10853, encryptionId=6505108534a, topicName=lgE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=beb613117181, createdName=HNYYM, createdTime=Wed Jul 15 04:09:43 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802732, encodeId=a4f0802e3295, content=学习了,很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83epbiavQw9picXSMXa5H7ZG9oW2IUumIqEJffFK1qfw7FS2XODCYRNmp6YlLwywwIZ2zxRVfGY0XHEnw/132, createdBy=67992544404, createdName=哈哈娜, createdTime=Tue Jul 14 09:38:39 CST 2020, time=2020-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802635, encodeId=6ad480263503, content=学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f435296195, createdName=ms3000000449926787, createdTime=Mon Jul 13 13:19:38 CST 2020, time=2020-07-13, status=1, ipAttribution=)]
    2020-07-15 1487d582m08暂无昵称

    好方法

    0

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    2020-07-15 小惠

    积分

    0

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    2020-07-15 李继鹏

    非常感谢

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1728598, encodeId=760b1e28598a0, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Aug 08 06:09:43 CST 2020, time=2020-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802858, encodeId=28ef80285859, content=好方法, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=83185307473, createdName=1487d582m08暂无昵称, createdTime=Wed Jul 15 12:55:18 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802837, encodeId=02f880283eb3, content=积分, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLJv7sDRP4SAgnKpriaexAiaLUgTpa8f4G8RcbH2ia1pRjHODZWtIJBPW7BctUSCC64odNklA6iaboiapQ/132, createdBy=797d2509270, createdName=小惠, createdTime=Wed Jul 15 09:01:31 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802824, encodeId=d9138028242b, content=非常感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eof7QgiaM40Cbk9nEupXmSOY1ibC6icYDYgtF7MMZoDnic7g0cyKqthJ2NLxE1WSiaib43H9DE4iaNQPFUBg/132, createdBy=9f9f5279032, createdName=李继鹏, createdTime=Wed Jul 15 07:13:48 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478697, encodeId=a58914e86976f, content=<a href='/topic/show?id=d561665e7af' target=_blank style='color:#2F92EE;'>#满意度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66577, encryptionId=d561665e7af, topicName=满意度)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1627448984, createdName=ms1692212821629096, createdTime=Wed Jul 15 04:09:43 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1539234, encodeId=54841539234c3, content=<a href='/topic/show?id=6505108534a' target=_blank style='color:#2F92EE;'>#lgE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10853, encryptionId=6505108534a, topicName=lgE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=beb613117181, createdName=HNYYM, createdTime=Wed Jul 15 04:09:43 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802732, encodeId=a4f0802e3295, content=学习了,很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83epbiavQw9picXSMXa5H7ZG9oW2IUumIqEJffFK1qfw7FS2XODCYRNmp6YlLwywwIZ2zxRVfGY0XHEnw/132, createdBy=67992544404, createdName=哈哈娜, createdTime=Tue Jul 14 09:38:39 CST 2020, time=2020-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802635, encodeId=6ad480263503, content=学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f435296195, createdName=ms3000000449926787, createdTime=Mon Jul 13 13:19:38 CST 2020, time=2020-07-13, status=1, ipAttribution=)]
    2020-07-15 HNYYM
  7. [GetPortalCommentsPageByObjectIdResponse(id=1728598, encodeId=760b1e28598a0, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sat Aug 08 06:09:43 CST 2020, time=2020-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802858, encodeId=28ef80285859, content=好方法, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=83185307473, createdName=1487d582m08暂无昵称, createdTime=Wed Jul 15 12:55:18 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802837, encodeId=02f880283eb3, content=积分, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLJv7sDRP4SAgnKpriaexAiaLUgTpa8f4G8RcbH2ia1pRjHODZWtIJBPW7BctUSCC64odNklA6iaboiapQ/132, createdBy=797d2509270, createdName=小惠, createdTime=Wed Jul 15 09:01:31 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802824, encodeId=d9138028242b, content=非常感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eof7QgiaM40Cbk9nEupXmSOY1ibC6icYDYgtF7MMZoDnic7g0cyKqthJ2NLxE1WSiaib43H9DE4iaNQPFUBg/132, createdBy=9f9f5279032, createdName=李继鹏, createdTime=Wed Jul 15 07:13:48 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1478697, encodeId=a58914e86976f, content=<a href='/topic/show?id=d561665e7af' target=_blank style='color:#2F92EE;'>#满意度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66577, encryptionId=d561665e7af, topicName=满意度)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d1627448984, createdName=ms1692212821629096, createdTime=Wed Jul 15 04:09:43 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1539234, encodeId=54841539234c3, content=<a href='/topic/show?id=6505108534a' target=_blank style='color:#2F92EE;'>#lgE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10853, encryptionId=6505108534a, topicName=lgE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=beb613117181, createdName=HNYYM, createdTime=Wed Jul 15 04:09:43 CST 2020, time=2020-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802732, encodeId=a4f0802e3295, content=学习了,很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83epbiavQw9picXSMXa5H7ZG9oW2IUumIqEJffFK1qfw7FS2XODCYRNmp6YlLwywwIZ2zxRVfGY0XHEnw/132, createdBy=67992544404, createdName=哈哈娜, createdTime=Tue Jul 14 09:38:39 CST 2020, time=2020-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=802635, encodeId=6ad480263503, content=学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f435296195, createdName=ms3000000449926787, createdTime=Mon Jul 13 13:19:38 CST 2020, time=2020-07-13, status=1, ipAttribution=)]
    2020-07-14 哈哈娜

    学习了,很有用

    0

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    2020-07-13 ms3000000449926787

    学习了!

    0

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