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J Clin Gastroenterol:胆囊切除术能降低胆系疾病发生率

2015-08-28 徐媛媛 MedSci原创

胆囊内胆泥至今还没有完全的定论。本研究旨在评估症状性胆囊内胆泥患者后期是否会发生胆系疾病。在这项研究中,研究人员对来自2003年5月至2012年12月典型胆系疼痛且接受过腹部超声检查的患者(排除患胆囊结石的患者)进行评估。本研究比较其中胆囊内胆泥患者与非胆囊内胆泥患者间急性胆囊炎、急性胆管炎和急性胰腺炎等胆系疾病的发生率。收纳了58名被诊断出患有胆囊内胆泥患者和70名未患胆囊内胆泥患者。对胆泥组患

胆囊内胆泥至今还没有完全的定论。本研究旨在评估症状性胆囊内胆泥患者后期是否会发生胆系疾病。

在这项研究中,研究人员对来自2003年5月至2012年12月典型胆系疼痛且接受过腹部超声检查的患者(排除患胆囊结石的患者)进行评估。本研究比较其中胆囊内胆泥患者与非胆囊内胆泥患者间急性胆囊炎、急性胆管炎和急性胰腺炎等胆系疾病的发生率。

收纳了58名被诊断出患有胆囊内胆泥患者和70名未患胆囊内胆泥患者。对胆泥组患者来说,5年累计胆系疾病发生率明显更高(33.9% vs 15.8%,P = 0.021),风险比(HR)为2.573(95% CI;1.124-5.889; P=0.025) ,与非胆泥组患者相比,胆泥组中每个胆系疾病5年累计发病率均更高(急性胆囊炎,15.6% vs 5.3%;急性胆管炎,15.5% vs 5.3%;急性胰腺炎18.4% vs 11.1%),后来行胆囊切除术的患者发生胆系疾病的人数更少(2/16,12.5% vs 17/42,40.4%;P = 0.067)。

症状性胆囊内胆泥患者更容易发生胆系疾病,且胆囊切除术能够减低发生率,因此胆囊内胆泥被认为是一个独立危险因素。

原始出处

Lee YS1, Kang BK, Hwang IK, Kim J, Hwang JH.Long-term Outcomes of Symptomatic Gallbladder Sludge.J Clin Gastroenterol. 2015 Aug;

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1710808, encodeId=9de51e1080853, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Sat Jun 18 05:01:00 CST 2016, time=2016-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876709, encodeId=efef18e670923, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Thu Mar 10 21:01:00 CST 2016, time=2016-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063923, encodeId=b19620639238a, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Wed Nov 11 22:01:00 CST 2015, time=2015-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826285, encodeId=c9cb18262853b, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Aug 12 16:01:00 CST 2016, time=2016-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1678987, encodeId=c03716e898702, content=<a href='/topic/show?id=df0a834328b' target=_blank style='color:#2F92EE;'>#胆囊切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83432, encryptionId=df0a834328b, topicName=胆囊切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4d227724361, createdName=huangshifeng, createdTime=Wed Jan 27 05:01:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429782, encodeId=de941429e82c6, content=<a href='/topic/show?id=140783434c7' target=_blank style='color:#2F92EE;'>#胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83434, encryptionId=140783434c7, topicName=胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3f94230600, createdName=yangfl07, createdTime=Sun Aug 30 09:01:00 CST 2015, time=2015-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36207, encodeId=5ff03620e3d, content=普外不懂得, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=06b21613993, createdName=STAR1234569, createdTime=Sat Aug 29 23:06:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36184, encodeId=04b9361843f, content=?, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=51a41609947, createdName=jiaoaoxiaoxu, createdTime=Sat Aug 29 13:19:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071583, encodeId=9f8a20e1583fe, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sat Sep 19 13:01:00 CST 2015, time=2015-09-19, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1710808, encodeId=9de51e1080853, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Sat Jun 18 05:01:00 CST 2016, time=2016-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876709, encodeId=efef18e670923, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Thu Mar 10 21:01:00 CST 2016, time=2016-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063923, encodeId=b19620639238a, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Wed Nov 11 22:01:00 CST 2015, time=2015-11-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1826285, encodeId=c9cb18262853b, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Fri Aug 12 16:01:00 CST 2016, time=2016-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1678987, encodeId=c03716e898702, content=<a href='/topic/show?id=df0a834328b' target=_blank style='color:#2F92EE;'>#胆囊切除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83432, encryptionId=df0a834328b, topicName=胆囊切除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f4d227724361, createdName=huangshifeng, createdTime=Wed Jan 27 05:01:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1429782, encodeId=de941429e82c6, content=<a href='/topic/show?id=140783434c7' target=_blank style='color:#2F92EE;'>#胆囊切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83434, encryptionId=140783434c7, topicName=胆囊切除术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d3f94230600, createdName=yangfl07, createdTime=Sun Aug 30 09:01:00 CST 2015, time=2015-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36207, encodeId=5ff03620e3d, content=普外不懂得, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=06b21613993, createdName=STAR1234569, createdTime=Sat Aug 29 23:06:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=36184, encodeId=04b9361843f, content=?, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=51a41609947, createdName=jiaoaoxiaoxu, createdTime=Sat Aug 29 13:19:00 CST 2015, time=2015-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071583, encodeId=9f8a20e1583fe, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Sat Sep 19 13:01:00 CST 2015, time=2015-09-19, status=1, ipAttribution=)]
    2015-08-29 STAR1234569

    普外不懂得

    0

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    2015-08-29 jiaoaoxiaoxu

    0

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    2015-09-19 许安

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