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Int J Pharm Investig：姜黄素和奥硝唑凝胶治疗慢性牙周炎孰优孰劣

2018-05-07 MedSci MedSci原创

姜黄素奥硝唑慢性牙周炎
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本研究旨在评估姜黄素和奥硝唑治疗慢性牙周炎的效果。 研究纳入了20名年龄在27至53岁之间的男性，诊断为慢性牙周炎，双侧均有探诊深度> 5mm的牙周袋。测量每名患者的菌斑指数、探诊深度和临床附着水平。患者接受完整的预防治疗，包括洁治和根面平整，之后将两种测试凝胶注射到两侧选定的两个实验位点，该位点探诊深度（PD）> 5mm，且对称。在第0天和第30天记录牙周袋PD，临床附着丧失和

本研究旨在评估姜黄素和奥硝唑治疗慢性牙周炎的效果。

研究纳入了20名年龄在27至53岁之间的男性，诊断为慢性牙周炎，双侧均有探诊深度> 5mm的牙周袋。测量每名患者的菌斑指数、探诊深度和临床附着水平。患者接受完整的预防治疗，包括洁治和根面平整，之后将两种测试凝胶注射到两侧选定的两个实验位点，该位点探诊深度（PD）> 5mm，且对称。在第0天和第30天记录牙周袋PD，临床附着丧失和菌斑指数。

结果显示，在1个月的评估中，与奥硝唑组相比，姜黄素组的口袋PD、斑块指数和临床附着丧失显著降低。

综上所述，该研究结果表明，姜黄素比奥硝唑凝胶在治疗牙周炎方面更有效，因此姜黄素可用作非手术牙周治疗的辅助剂。

原始出处：

Ravishankar PL, Kumar YP, et al., Effect of local application of curcumin and ornidazole gel in chronic periodontitis patients. Int J Pharm Investig. 2017 Oct-Dec;7(4):188-192. doi: 10.4103/jphi.JPHI_82_17.

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    2018-05-13 xiangyuzhou971

    #EST#

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    2018-08-18 jj000001

    #Pharm#

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    2018-05-11 lyh994

    天然色素姜黄素

    0

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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Mon May 07 23:31:04 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
    2018-05-09 piaojinhua

    #慢性牙周炎#

    0

  5. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Mon May 07 23:31:04 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
    2018-05-09 liuyong2982

    #牙周#

    0

  6. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue May 08 06:24:15 CST 2018, time=2018-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313007, encodeId=1fb131300ec9, content=追踪热点, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc242342194, createdName=12292ceem27暂无昵称, createdTime=Tue May 08 04:38:30 CST 2018, time=2018-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312979, encodeId=17ab3129e950, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Mon May 07 23:31:04 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
    2018-05-09 lishizhe

    #凝胶#

    0

  7. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue May 08 06:24:15 CST 2018, time=2018-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313007, encodeId=1fb131300ec9, content=追踪热点, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc242342194, createdName=12292ceem27暂无昵称, createdTime=Tue May 08 04:38:30 CST 2018, time=2018-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312979, encodeId=17ab3129e950, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Mon May 07 23:31:04 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
    2018-05-09 sunfeifeiyang

    阅

    0

  8. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue May 08 06:24:15 CST 2018, time=2018-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313007, encodeId=1fb131300ec9, content=追踪热点, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc242342194, createdName=12292ceem27暂无昵称, createdTime=Tue May 08 04:38:30 CST 2018, time=2018-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312979, encodeId=17ab3129e950, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Mon May 07 23:31:04 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
    2018-05-08 飛歌

    厉害了我的哥

    0

  9. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue May 08 06:24:15 CST 2018, time=2018-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313007, encodeId=1fb131300ec9, content=追踪热点, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc242342194, createdName=12292ceem27暂无昵称, createdTime=Tue May 08 04:38:30 CST 2018, time=2018-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312979, encodeId=17ab3129e950, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Mon May 07 23:31:04 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
    2018-05-08 12292ceem27暂无昵称

    追踪热点

    0

  10. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue May 08 06:24:15 CST 2018, time=2018-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313007, encodeId=1fb131300ec9, content=追踪热点, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bc242342194, createdName=12292ceem27暂无昵称, createdTime=Tue May 08 04:38:30 CST 2018, time=2018-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=312979, encodeId=17ab3129e950, content=^_^^_^^_^, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Swp2ehfHpiciczeTntUyQOlIGMzQ705ic67sdMTVMbwTv7KbmlUvxrGvRSvQZjPkz7ib5tEDfIaORgczPtmHDpwojg/0, createdBy=c54b2163125, createdName=wqkm, createdTime=Mon May 07 23:31:04 CST 2018, time=2018-05-07, status=1, ipAttribution=)]
    2018-05-07 wqkm

    ^_^^_^^_^

    0

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