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J Transl Med:多孔半月板植入物可以用于防止关节软骨过度受力

2019-11-04 不详 网络

人工半月板植入物可用于替代半月板切除术后严重受伤的半月板,并恢复膝关节的正常功能。本研究旨在设计多孔半月板植入物并评估其生物力学性能。在八种不同情况下进行了有限元模拟,包括完整的健康膝盖,带有坚固半月板植入物的膝关节以及带有半月板植入物的膝关节的两种类型的三重周期性最小周期曲面。使用1150 N的轴向压缩载荷和350 N的前向载荷评估了压缩应力,剪切应力和应力集中区域的特性。结果显示,与固态半月板

人工半月板植入物可用于替代半月板切除术后严重受伤的半月板,并恢复膝关节的正常功能。本研究旨在设计多孔半月板植入物并评估其生物力学性能。

在八种不同情况下进行了有限元模拟,包括完整的健康膝盖,带有坚固半月板植入物的膝关节以及带有半月板植入物的膝关节的两种类型的三重周期性最小周期曲面。使用1150 N的轴向压缩载荷和350 N的前向载荷评估了压缩应力,剪切应力和应力集中区域的特性。

结果显示,与固态半月板植入物相比,多孔半月板植入物在软骨上产生较低水平的压缩应力和剪切应力,这有助于软骨保持类似于天然半月板的半月形特征。此外,已发现人造软骨上的压缩应力和剪切应力均对半月板植入物的孔特性敏感。具有原始表面(孔隙度:41%)的半月板植入物在散布膝关节内的应力方面表现出更好的性能。

综上所述,该研究结果表明,与天然半月板相比,目前的商业半月板植入物具有等效的生物力学性质的问题。所提出的多孔结构的主要优点是,它可以用于防止关节软骨过度压缩和剪切应力。该结构在力学和可打印制造方面均具有优势,这对于将来的临床应用可能是有益的。

原始出处:

Zhu LY, Li L, et al., Design and biomechanical characteristics of porous meniscal implant structures using triplyperiodic minimal surfaces. J Transl Med. 2019 Mar 18;17(1):89. doi: 10.1186/s12967-019-1834-2.

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    2020-06-30 bsmagic9140
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    2020-01-09 anan
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1657247, encodeId=a2af165e2471b, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=757b24868428, createdName=bsmagic9140, createdTime=Tue Jun 30 15:59:00 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2067465, encodeId=f15b206e46557, content=<a href='/topic/show?id=d0841e75535' target=_blank style='color:#2F92EE;'>#Transl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17755, encryptionId=d0841e75535, topicName=Transl)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Fri Dec 13 20:59:00 CST 2019, time=2019-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1735908, encodeId=fa191e3590804, content=<a href='/topic/show?id=2af23014609' target=_blank style='color:#2F92EE;'>#关节软骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30146, encryptionId=2af23014609, topicName=关节软骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=165434038855, createdName=anan, createdTime=Thu Jan 09 15:59:00 CST 2020, time=2020-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346498, encodeId=dfb6134649820, content=<a href='/topic/show?id=8ae43581977' target=_blank style='color:#2F92EE;'>#半月板#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35819, encryptionId=8ae43581977, topicName=半月板)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490927, encodeId=c2ab149092e03, content=<a href='/topic/show?id=fb916268636' target=_blank style='color:#2F92EE;'>#植入物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62686, encryptionId=fb916268636, topicName=植入物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=38628846382, createdName=linagood, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520630, encodeId=af60152063071, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610104, encodeId=15191610104bd, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1657247, encodeId=a2af165e2471b, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=757b24868428, createdName=bsmagic9140, createdTime=Tue Jun 30 15:59:00 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2067465, encodeId=f15b206e46557, content=<a href='/topic/show?id=d0841e75535' target=_blank style='color:#2F92EE;'>#Transl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17755, encryptionId=d0841e75535, topicName=Transl)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Fri Dec 13 20:59:00 CST 2019, time=2019-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1735908, encodeId=fa191e3590804, content=<a href='/topic/show?id=2af23014609' target=_blank style='color:#2F92EE;'>#关节软骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30146, encryptionId=2af23014609, topicName=关节软骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=165434038855, createdName=anan, createdTime=Thu Jan 09 15:59:00 CST 2020, time=2020-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346498, encodeId=dfb6134649820, content=<a href='/topic/show?id=8ae43581977' target=_blank style='color:#2F92EE;'>#半月板#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35819, encryptionId=8ae43581977, topicName=半月板)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490927, encodeId=c2ab149092e03, content=<a href='/topic/show?id=fb916268636' target=_blank style='color:#2F92EE;'>#植入物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62686, encryptionId=fb916268636, topicName=植入物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=38628846382, createdName=linagood, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520630, encodeId=af60152063071, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610104, encodeId=15191610104bd, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=)]
    2019-11-06 jiyangfei
  7. [GetPortalCommentsPageByObjectIdResponse(id=1657247, encodeId=a2af165e2471b, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=757b24868428, createdName=bsmagic9140, createdTime=Tue Jun 30 15:59:00 CST 2020, time=2020-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2067465, encodeId=f15b206e46557, content=<a href='/topic/show?id=d0841e75535' target=_blank style='color:#2F92EE;'>#Transl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17755, encryptionId=d0841e75535, topicName=Transl)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Fri Dec 13 20:59:00 CST 2019, time=2019-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1735908, encodeId=fa191e3590804, content=<a href='/topic/show?id=2af23014609' target=_blank style='color:#2F92EE;'>#关节软骨#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30146, encryptionId=2af23014609, topicName=关节软骨)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=165434038855, createdName=anan, createdTime=Thu Jan 09 15:59:00 CST 2020, time=2020-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346498, encodeId=dfb6134649820, content=<a href='/topic/show?id=8ae43581977' target=_blank style='color:#2F92EE;'>#半月板#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=35819, encryptionId=8ae43581977, topicName=半月板)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1490927, encodeId=c2ab149092e03, content=<a href='/topic/show?id=fb916268636' target=_blank style='color:#2F92EE;'>#植入物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62686, encryptionId=fb916268636, topicName=植入物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=38628846382, createdName=linagood, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1520630, encodeId=af60152063071, content=<a href='/topic/show?id=7a736264553' target=_blank style='color:#2F92EE;'>#植入#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62645, encryptionId=7a736264553, topicName=植入)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=832411313664, createdName=jiyangfei, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1610104, encodeId=15191610104bd, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Wed Nov 06 05:59:00 CST 2019, time=2019-11-06, status=1, ipAttribution=)]
    2019-11-06 智慧医人
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