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JACC:射血分数对心衰患者预后是否有影响?

2017-11-15 MedSci MedSci原创

心衰患者预后差,并且可根据射血分数来分类。本研究的目的旨在评估住院心衰患者伴保留型射血分数(HFpEF) (EF ≥50%)、心衰患者伴边缘型射血分数(HFbEF) (EF 41% - 49%)和心衰患者伴减少型射血分数(HFrEF) (EF ≤40%)预后结局的差异。本研究共纳入2005年至2009年来自254家医院被诊断为心衰的39982名患者,其中,18299名患者 (46%) 为HFpEF

心衰患者预后差,并且可根据射血分数来分类。

本研究的目的旨在评估住院心衰患者伴保留型射血分数(HFpEF) (EF ≥50%)、心衰患者伴边缘型射血分数(HFbEF) (EF 41% - 49%)和心衰患者伴减少型射血分数(HFrEF) (EF ≤40%)预后结局的差异。

本研究共纳入2005年至2009年来自254家医院被诊断为心衰的39982名患者,其中,18299名患者 (46%) 为HFpEF,,3285名患者 (8.2%) 为HFbEF,18398名患者 (46%) 为HFrEF,总体平均生存时间为2.1年,风险调整生存分析后,三组患者的5年死亡率相似(HFrEF 75.3% vs. HFpEF 75.7%;HR: 0.99 [95% Cl: 0.958 - 1.022]; HFbEF 75.7% vs. HFpEF 75.7%; HR: 0.99 [95% Cl: 0.947 - 1.046]),复合死亡率和再住院率在各亚组中也无明显差异。心源性和心衰再住院率在HFrEF 和HFbEF患者中更高。此外,与美国正常人群相比,所有年龄段和射血分数亚组的心衰患者生存时间更低。

研究结果显示,在住院的心衰患者中,各射血分数亚组患者的5年生存率相似,心源性和心衰再住院率均升高。

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    2018-06-08 hbwxf
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