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JAMA Dermat:20岁之后还生痤疮的男性,要当心患糖尿病的风险了

2015-12-26 Mechront 译 MedSci原创

男性痤疮患者代谢综合征与胰岛素抵抗情况相关研究很少,因此研究者进行了一项研究,探究≥20岁男性痤疮患者其代谢综合征与胰岛素抵抗的关系。该横断面研究纳入了100名男性痤疮患者,100名年龄配对的无痤疮的男性对照组。根据痤疮综合分级系统将患者分为严重性不同的4组,每组25名患者。根据修订的 NCEP-ATP III诊断代谢综合征,通过 HOMA-IR评估胰岛素抵抗情况,HOMA-IR值>2.5认为是胰

男性痤疮患者代谢综合征与胰岛素抵抗情况相关研究很少,因此研究者进行了一项研究,探究≥20岁男性痤疮患者其代谢综合征与胰岛素抵抗的关系。

该横断面研究纳入了100名男性痤疮患者,100名年龄配对的无痤疮的男性对照组。根据痤疮综合分级系统将患者分为严重性不同的4组,每组25名患者。根据修订的 NCEP-ATP III诊断代谢综合征,通过 HOMA-IR评估胰岛素抵抗情况,HOMA-IR值>2.5认为是胰岛素抵抗。

研究数据显示,痤疮组胰岛素抵抗发生率高于对照组(22% vs. 11%,P=.03)。痤疮组和对照组代谢综合征的患病率相当(17% vs.9%,P = .09)。不同严重程度痤疮组间胰岛素抵抗和代谢综合症发病率无差异。

研究结果表明,青壮年痤疮男性极有可能伴有胰岛素抵抗,可能导致前驱糖尿病,未来高胰岛素血症或2型糖尿病风险更高。应对该类患者随访较长时间,以探究该胰岛素抵抗是否会导致其他疾病的出现。

原始出处:

Mohit Nagpal, Dipankar De, et al.Insulin Resistance and Metabolic Syndrome in Young Men With Acne.JAMA Dermatol. Published online December 23, 2015. doi:10.1001/jamadermatol.2015.4499


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    2016-05-18 三毛坨

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    2016-05-18 三毛坨

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    2016-05-18 三毛坨

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    2016-05-18 三毛坨

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    2016-05-18 三毛坨

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    2016-05-18 三毛坨

    Xbbfh

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