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Clin Microbiol Infec:警惕:出现一些症状后即使尿检阴性也可能是膀胱炎!

2017-05-01 枫丹白露 来宝网

大多数女性在排尿时疼痛,或需要小便或尿急,可能会有细菌感染,即使尿液检测不到任何症状。

大多数女性在排尿时疼痛,或需要小便或尿急,可能会有细菌感染,即使尿液检测不到任何症状。

尿路感染(UTI)如膀胱炎是的症状在女性中很常见,但在四分之一的病例中,使用标准检测未发现感染。

然而,临床微生物学和感染发表的新研究和使用更敏感的检测发现几乎所有尿路感染症状的妇女都有细菌感染的证据,包括那些在标准检测中没有发现细菌的细菌感染。

由比利时根特大学Stefan Heytens博士领导的这项研究支持这样一种观点,即对具有不复杂UTI症状的妇女进行检测是不必要的。

泌尿系统症状占妇女GP诊断的2-5%。在60-80%的情况下,尿液测试显示细菌感染。

测试包括使用实验室技术来检测尿液中的细菌。

这些妇女可能会使用抗生素如呋喃妥因、甲氧苄氨嘧啶或磷霉素。

然而,医生们认为阴性检测的妇女没有细菌感染。在过去,这组妇女可能被诊断为不明原因的“尿道综合征”,一些研究者认为这可能是心身疾病。

Heytens博士,根特大学家庭医学和初级卫生保健部门的研究员,解释说:“大部分因尿路感染症状而去看医生的妇女,细菌感染试验阴性时,被告知他们没有感染,并回家不治疗。

“另一方面,积极测试的妇女可能会接受短期的抗生素治疗他们的感染。”

新的研究涉及308名比利时妇女,其中包括220名检测他们的GP为UTI症状和86名健康志愿者。所有的妇女都给出尿液样本。

尿液样本以标准的方式进行了测试,看看是否有细菌生长。他们还使用了一种叫做定量聚合酶链反应检测。这种技术是非常敏感的,可以用来检测来自引起尿路感染的细菌的微小数量的DNA,如大肠杆菌(大肠杆菌)和staphloccocus腐生葡萄球菌(S. saphrophyticus)。

在泌尿系统症状的妇女中,标准检测发现80.9%的尿液样本中有细菌。但是qPCR测试发现95.9%含有大肠杆菌,8.6%含有美国saphrophyticus。结合这两项测试的结果,发现98.2%的妇女有感染症状的证据。

在没有症状的妇女中,标准测试中10.5%含大肠杆菌,qPCR中11.6%含有大肠杆菌。

Heytens博士说:“在这项研究中,我们使用了一个更为敏感的测试来检查引起尿路感染的细菌。我们发现检测到大肠杆菌的几乎所有的妇女都抱怨自己有相关症状,即使她们传统尿培养为阴性。这表明,如果一个女人有这些症状,她可能有泌尿道感染。

“我们的研究结果支持以前的研究表明,传统的测试可能不简单是有帮助的。然而,传统的尿培养试验可能仍然发挥作用,不管治疗失败还是有一个更复杂的尿路感染的症状和体征。

“我们不知道的是,所有这些症状的妇女是否会受益于一个疗程的抗生素。”

Heytens博士说,研究结果需要进一步的研究证实。他和他的同事们还计划研究是否具有尿路感染症状但尿测试阴性的妇女能从抗生素治疗中获益,以及他们是否可以使用qPCR检测可能引起尿路感染的其他类型的细菌。

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    2018-04-13 sunylz
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    2017-07-06 xjy02
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content=谢谢分享,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Tue May 02 15:49:31 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
  4. 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  5. 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content=谢谢分享,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Tue May 02 15:49:31 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-09 小大夫快跑

    学习了

    0

  6. 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content=谢谢分享,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Tue May 02 15:49:31 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-08 虈亣靌

    好好学习,涨知识

    0

  7. 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topicName=Biol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=446937890434, createdName=12498ebem31暂无昵称, createdTime=Wed Nov 01 15:45:00 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195579, encodeId=c9741955e9fc, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5Rzegz2kicwSDGST4gkzMm8229KtEaV7JEushLtsOJ4OweeyQ7oiaqU73G1eVialdQSZrH7DWxTgR8pYZ/0, createdBy=e81f1959878, createdName=小大夫快跑, createdTime=Tue May 09 02:21:20 CST 2017, time=2017-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=195420, encodeId=1b9d195420f8, content=好好学习,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], 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content=谢谢分享,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Tue May 02 15:49:31 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-04 一个字-牛

    临床这种情况多见

    0

  8. 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  9. 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content=谢谢分享,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Tue May 02 15:49:31 CST 2017, time=2017-05-02, status=1, ipAttribution=)]
    2017-05-03 龙胆草

    学习了,谢谢分享

    0

  10. 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    2017-05-02 明月清辉

    谢谢分享,学习

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