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Diabetic Med:多胎分娩和种族对糖尿病发展风险的影响?

2018-01-04 MedSci MedSci原创

近日,国际杂志 《Diabetic Med》上在线发表一项关于多胎分娩和种族对糖尿病发展风险的影响的基于群体的队列研究。研究人员调查基于大型人口群体中增加分娩次数与糖尿病之间的关系,并研究高危族群之间的这种关系是否不同。 对安哥拉738 440名年龄在18-50岁之间在2007年4月1日至2011年3月31日期间分娩的人群进行回顾性队列研究。研究人员为每个胎次和种族群体计算了产后糖尿病发病率

近日,国际杂志 《Diabetic Med》上在线发表一项关于多胎分娩和种族对糖尿病发展风险的影响的基于群体的队列研究。研究人员调查基于大型人口群体中增加分娩次数与糖尿病之间的关系,并研究高危族群之间的这种关系是否不同。

对安哥拉738 440名年龄在18-50岁之间在200741日至2011331日期间分娩的人群进行回顾性队列研究。研究人员为每个胎次和种族群体计算了产后糖尿病发病率。使用Cox比例风险模型,对混合因素进行校正,对胎次和种族对糖尿病发病率的影响进行多变量分析。

研究发现,糖尿病发病率为每1000人年3.69,分娩3次的女性为4.12,女性≥5次分娩的为7.62。大于等于3次分娩经历的女性与分娩1次女性相比,发生糖尿病的风险更高[3次分娩的校正风险比为1.0695CI 1.01-1.11),4次为1.3395CI1.25-1.43),5次为(95CI 1.41-1.66)。中国和南亚妇女的风险有类似的上升,且对中国妇女影响最大[风险比为4.5995CI 2.36-8.92)≥5]

研究表明,分娩次数与糖尿病发展风险之间存在着正向和分等级的关系。在所有种族中都观察到分娩次数的影响。这种关联可能部分程度上与体重增加和分娩增加,或β细胞功能的恶化有关。这值得进一步探索。

原始出处:

B. Almahmeed, B. R. Shah, G. Mukerjiet al. Effect of multiparity and ethnicity on the risk of development of diabetes: a large population-based cohort study

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    2018-01-06 linlin2312
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1760460, encodeId=62371e60460ca, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Sat Nov 10 21:50:00 CST 2018, time=2018-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1970566, encodeId=88a919e0566cd, content=<a href='/topic/show?id=fa5d5919df' target=_blank style='color:#2F92EE;'>#Diabetic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5919, encryptionId=fa5d5919df, topicName=Diabetic)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8949377, createdName=chenzhuanggui, createdTime=Sat Jun 30 03:50:00 CST 2018, time=2018-06-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638329, encodeId=782c163832900, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Jun 20 14:50:00 CST 2018, time=2018-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275131, encodeId=992812e51311c, content=<a href='/topic/show?id=263031541b4' target=_blank style='color:#2F92EE;'>#分娩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31541, encryptionId=263031541b4, topicName=分娩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Sat Jan 06 05:50:00 CST 2018, time=2018-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608413, encodeId=42e3160841302, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sat Jan 06 05:50:00 CST 2018, time=2018-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=275424, encodeId=fbb92e54241a, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Thu Jan 04 15:43:40 CST 2018, time=2018-01-04, status=1, ipAttribution=)]
    2018-01-04 1e0f8808m18(暂无匿称)

    学习了.谢谢分享.

    0

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