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Stroke:短暂性脑缺血发作中孤立性非典型短暂性症状的临床意义!

2017-05-10 xing.T MedSci原创

由此可见,短暂性缺血发作的诊断应考虑和研究孤立性非典型TS患者。

与典型的短暂性症状(TS)相反,非典型的TS,如局部感觉障碍、构音障碍、眩晕、步态不稳、不寻常的皮层视觉缺失、复视,通常不被归类为短暂性脑缺血发作的症状,当它们单独发生时,其临床意义经常被否认。

近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员对其所在的短暂性脑缺血发作诊所(2003-2008年)连续就诊的近期TS患者进行了系统的脑、动脉和心脏检查。在排除主要鉴别诊断后,研究人员比较了孤立的典型或非典型TS患者和非孤立的TS患者脑成像图像上近期脑梗死的患病率、主要调查结果(症状性颅内或颅外动脉狭窄≥50%、颈动脉夹层和主要来源于心脏的栓塞)和主要血管事件的1年风险。

在1850例可能或明确的缺血性诊断患者中,有798例(43.1%)患者为孤立性TS:621例为典型TS患者(33.6%)和177例为非典型TS患者(9.6%)。脑成像图像上急性脑梗死发生情况在孤立的非典型TS患者和典型TS患者之间类似,但是比非孤立的TS患者更不频繁,观察的发生率分别为10%、11.5%和15.3%(P<0.0001)。主要调查结果分在18.1%、26.4%和26.3%的患者中可以观察到(P=0.06)。3组间大血管事件的1年风险差异无统计学意义。

由此可见,短暂性缺血发作的诊断应考虑和研究孤立性非典型TS患者。

原始出处:

Philippa C. Lavallée,et al. Clinical Significance of Isolated Atypical Transient Symptoms in a Cohort With Transient Ischemic Attack.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.117.016743

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  5. 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    2017-05-12 jxrzshh
  6. 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content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-11 尹玉伟

    学习了……厉害几次

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Thu May 11 06:30:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196355, encodeId=887f19635583, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Thu May 11 00:13:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196309, encodeId=226e1963099b, content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-11 meiliwuxian

    非常不错!学习了

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Thu May 11 06:30:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196355, encodeId=887f19635583, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Thu May 11 00:13:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196309, encodeId=226e1963099b, content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-11 jacob9231

    谢谢分享,学习了

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Thu May 11 06:30:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196355, encodeId=887f19635583, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Thu May 11 00:13:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196309, encodeId=226e1963099b, content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-11 tanxingdoctor

    学习了,谢谢分享

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM66WRRAmeqIVSnDN88DpaJfEWzRZxg4yBbiaBmMRwcvViaA2C0sE0Ts3Lic24JSSI4YffujDtpnm0GTHpuiao9TytmNArrcYESnSXY/0, createdBy=7938104912, createdName=jacob9231, createdTime=Thu May 11 06:30:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196355, encodeId=887f19635583, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Thu May 11 00:13:05 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196309, encodeId=226e1963099b, content=短暂脑缺血发作,应引起重视。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed May 10 19:04:09 CST 2017, time=2017-05-10, status=1, ipAttribution=)]
    2017-05-10 1e0f8808m18(暂无匿称)

    短暂脑缺血发作,应引起重视。

    0

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因此,研究结果表明房颤不仅在缺血性卒中患者中是非常普遍,而且在TIA患者中随着年龄的增长,房颤发生比例也急剧增加。在TIA和缺血性卒中患者中,有相当比例的患者房颤患者出院时未进行抗凝治疗。

盘点:众多研究表明:带状疱疹增加心脑血管疾病风险

带状疱疹是由水痘-带状疱疹病毒所致的急性皮肤黏膜感染性疾病。临床上以突然发生的、沿神经带状分布、单侧分布、密集成群的疱疹为特点,疼痛明显,愈后极少复发。带状疱疹患者不能直接传播带状疱疹病毒,但能在易感人群中造成水痘流行。其传播途径仍为“皮肤-空气-呼吸道”。小儿感染VZV(初发感染)临床表现为水痘,成人表现为带状疱疹。带状疱疹感染在成人约占10%~20%,但以老年人及免疫缺陷者多见。局部外伤、部分

Neurology:糖代谢异常可增加轻型卒中患者卒中再发的风险

目的:为了探讨葡萄糖调节异常是否增加轻型缺血性卒中或TIA患者新发卒中。方法:研究者从急性非致残性脑血管事件高危患者氯吡格雷试验中获得数据,轻型卒中或TIA患者随机分为3组:糖尿病(DM)、空腹血糖受损(IFG),与空腹血糖正常。主要预后为90天内新发卒中(缺血性或出血性)。研究者应用多变量Cox回归模型,校正潜在的协变量,评估糖调节状态和卒中风险潜在的相关性。结果:5135例患者中,糖尿病、空腹

JAHA:年轻人要警惕卒中和TIA

背景:研究报告称,年轻成人缺血性脑卒中的发病率高于50岁至55岁的成年人。对其他亚型的卒中和短暂性脑缺血发作(TIA)的时间趋势信息是不足的。本研究的目的是探讨年龄15岁至30岁TIA和卒中住院率的变化趋势,包括性别和亚型特异性趋势。方法和结果:从丹麦国家病人登记记录中,研究者确定在丹麦所有1994-2012年住院的首次卒中和TIA患者(年龄15-30岁)。采用泊松回归估计估计年度百分比变化率(E

Neurology:轻微缺血性卒中或TIA患者进行氯吡格雷联合阿司匹林治疗的风险和益处!

由此可见,在轻微缺血性卒中或TIA患者中,氯吡格雷联合阿司匹林治疗相比于单独阿司匹林治疗,可能有利于降低卒中风险,并且超过了增加出血的潜在风险,特别是在前2周内。

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