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Circ Cardi Interv:警惕冠脉导丝涂层脱落致远端栓塞

2015-02-09 高晓方 译 医学论坛网

荷兰一项研究表明,经皮冠脉介入治疗(PCI)后冠脉导丝亲水涂层脱落导致远端栓塞的情况较为常见。论文1月23日在线发表于《循环:心血管介入》(Circulation: Cardiovascular Interventions)。 此项研究对205例血栓抽吸物和40例尸检样本进行了评估,以明确冠脉导丝亲水涂层脱落并栓塞远端微血管系统的发生频率。 结果显示,45%的血栓切面存在异物,

荷兰一项研究表明,经皮冠脉介入治疗(PCI)后冠脉导丝亲水涂层脱落导致远端栓塞的情况较为常见。论文1月23日在线发表于《循环:心血管介入》(Circulation: Cardiovascular Interventions)。


此项研究对205例血栓抽吸物和40例尸检样本进行了评估,以明确冠脉导丝亲水涂层脱落并栓塞远端微血管系统的发生频率。

结果显示,45%的血栓切面存在异物,10%的尸检样本远端心肌可见亲水涂层栓塞。“HT Whisper”导丝应用后最可能发现异物(71%),其次为“HT BMW Universal”(46%)和“HT Floppy”(19%)

研究者表示,无论在稳定性心绞痛或因ST段抬高型心梗行经皮PCI的患者中,与冠脉导丝亲水涂层栓塞相关的临床后果仍均有待明确。尽管如此,目前推测心肌内动脉被异物阻塞所致微栓塞可影响心功能。未来需明确亲水涂层在通过和示踪方面的益处是否超过其远端栓塞风险。

除外导丝,医生还应注意导管和球囊含有的这种高分子涂层也有可能导致血管内栓塞。另外,亲水导丝也不尽相同,一些导丝的涂层可能更容易脱落。

原始出处:

Will Boggs,Distal Embolization of Coronary Guidewire Coating Common,Medscape February 04, 2015

Grundeken MJ1, Li X1, Kurpershoek CE1, Kramer MC1, Vink A1, Piek JJ1, Tijssen JG1, Koch KT1, Wykrzykowska JJ1, de Winter RJ1, van der Wal AC2.Distal embolization of hydrophilic-coating material from coronary guidewires after percutaneous coronary interventions.Circ Cardiovasc Interv. 2015 Feb;8(2). pii: e001816. doi: 10.1161/CIRCINTERVENTIONS.114.001816..


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  1. [GetPortalCommentsPageByObjectIdResponse(id=1655238, encodeId=40861655238b4, content=<a href='/topic/show?id=05984668e6a' target=_blank style='color:#2F92EE;'>#导丝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46687, encryptionId=05984668e6a, topicName=导丝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=98f124702487, createdName=lingqf, createdTime=Sun Mar 29 18:07:00 CST 2015, time=2015-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16358, encodeId=c3eb1635864, content=几率很小吧,没有遇到过, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Feb 18 10:24:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16183, encodeId=ec10161831a, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=184, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da6b7222, createdName=chinayinhan, createdTime=Tue Feb 17 00:51:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15845, encodeId=de5015845be, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:22:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15540, encodeId=7cad1554076, content=是吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=188, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Sun Feb 15 20:39:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-03-29 lingqf
  2. [GetPortalCommentsPageByObjectIdResponse(id=1655238, encodeId=40861655238b4, content=<a href='/topic/show?id=05984668e6a' target=_blank style='color:#2F92EE;'>#导丝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46687, encryptionId=05984668e6a, topicName=导丝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=98f124702487, createdName=lingqf, createdTime=Sun Mar 29 18:07:00 CST 2015, time=2015-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16358, encodeId=c3eb1635864, content=几率很小吧,没有遇到过, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Feb 18 10:24:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16183, encodeId=ec10161831a, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=184, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da6b7222, createdName=chinayinhan, createdTime=Tue Feb 17 00:51:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15845, encodeId=de5015845be, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:22:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15540, encodeId=7cad1554076, content=是吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=188, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Sun Feb 15 20:39:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-02-18 午夜星河

    几率很小吧,没有遇到过

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1655238, encodeId=40861655238b4, content=<a href='/topic/show?id=05984668e6a' target=_blank style='color:#2F92EE;'>#导丝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46687, encryptionId=05984668e6a, topicName=导丝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=98f124702487, createdName=lingqf, createdTime=Sun Mar 29 18:07:00 CST 2015, time=2015-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16358, encodeId=c3eb1635864, content=几率很小吧,没有遇到过, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Feb 18 10:24:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16183, encodeId=ec10161831a, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=184, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da6b7222, createdName=chinayinhan, createdTime=Tue Feb 17 00:51:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15845, encodeId=de5015845be, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:22:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15540, encodeId=7cad1554076, content=是吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=188, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Sun Feb 15 20:39:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-02-17 chinayinhan

    已阅

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1655238, encodeId=40861655238b4, content=<a href='/topic/show?id=05984668e6a' target=_blank style='color:#2F92EE;'>#导丝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46687, encryptionId=05984668e6a, topicName=导丝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=98f124702487, createdName=lingqf, createdTime=Sun Mar 29 18:07:00 CST 2015, time=2015-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16358, encodeId=c3eb1635864, content=几率很小吧,没有遇到过, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Feb 18 10:24:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16183, encodeId=ec10161831a, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=184, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da6b7222, createdName=chinayinhan, createdTime=Tue Feb 17 00:51:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15845, encodeId=de5015845be, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:22:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15540, encodeId=7cad1554076, content=是吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=188, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Sun Feb 15 20:39:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-02-16 windmilL1989

    已阅

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1655238, encodeId=40861655238b4, content=<a href='/topic/show?id=05984668e6a' target=_blank style='color:#2F92EE;'>#导丝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46687, encryptionId=05984668e6a, topicName=导丝)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=98f124702487, createdName=lingqf, createdTime=Sun Mar 29 18:07:00 CST 2015, time=2015-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16358, encodeId=c3eb1635864, content=几率很小吧,没有遇到过, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200609/ef6a57dbe7f1489dad7446b7c5217858/d5e4fe65996c4446a029b0f5d056abb1.jpg, createdBy=6b011518214, createdName=午夜星河, createdTime=Wed Feb 18 10:24:00 CST 2015, time=2015-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=16183, encodeId=ec10161831a, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=184, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=da6b7222, createdName=chinayinhan, createdTime=Tue Feb 17 00:51:00 CST 2015, time=2015-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15845, encodeId=de5015845be, content=已阅, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c68e1614119, createdName=windmilL1989, createdTime=Mon Feb 16 14:22:00 CST 2015, time=2015-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=15540, encodeId=7cad1554076, content=是吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=188, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=928e1615200, createdName=jianlion, createdTime=Sun Feb 15 20:39:00 CST 2015, time=2015-02-15, status=1, ipAttribution=)]
    2015-02-15 jianlion

    是吗

    0

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