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Diabetes Care:适当饮用葡萄酒对二型糖尿病患者有益

2014-04-17 佚名 Medscape

最新数据表明Ⅱ型糖尿病病人适度饮葡萄酒能够减少心血管事件以及各种原因引起死亡的发生率。 之前有研究证实,Ⅱ型糖尿病病人总葡萄酒摄入量与心血管事件发生率之间存在U型关系,但过度饮用葡萄酒弊大于利。专家建议:“如果你只是适度饮用葡萄酒,不需要戒;如果你过度饮用葡萄酒,那么请减量;如果你不喝葡萄酒,那也没什么好担心的。喝葡萄酒唯一正当的理由的是你觉得那是一种享受。” 问题核心:喝葡萄酒的好处 虽然

最新数据表明Ⅱ型糖尿病病人适度饮葡萄酒能够减少心血管事件以及各种原因引起死亡的发生率。

之前有研究证实,Ⅱ型糖尿病病人总葡萄酒摄入量与心血管事件发生率之间存在U型关系,但过度饮用葡萄酒弊大于利。专家建议:“如果你只是适度饮用葡萄酒,不需要戒;如果你过度饮用葡萄酒,那么请减量;如果你不喝葡萄酒,那也没什么好担心的。喝葡萄酒唯一正当的理由的是你觉得那是一种享受。”

问题核心:喝葡萄酒的好处

虽然在适度饮用葡萄酒者中,葡萄酒摄入量与研究结果并无显著的相关性,但是过度饮用葡萄酒者发生心血管事件及各种原因所致的死亡率均增高。适度饮用葡萄酒对于心血管有一定的好处,数据表明:与不喝葡萄酒者相比,喝葡萄酒者心血管事件发生率降低22%(p=0.01),各种原因所致死亡率降低23%(p=0.02),但是微血管并发症发生率并无明显下降(p=0.12)。作为对比,饮用啤酒或白酒对研究结局没有明显影响。

专家认为,适度酒精摄入之所以对于心血管有好处是因为高密度脂蛋白胆固醇升高、炎症反应降低、胰岛素敏感性升高,这些与Ⅱ型糖尿病或有Ⅱ型糖尿病倾向的病人息息相关。然而,酒精的作用十分复杂且在很大程度上取决于饮酒量。适度饮酒或许还有其他的好处,但是过度饮酒的弊大于利,如卡路里摄入增加、酒精相关性心肌病、房颤发生率增高、肝损伤及社会影响等。

有研究表明,喝少许红酒或许可以提高内皮细胞的功能。但饮酒者通常肥胖者较少,运动较多,更可能用餐时饮酒,这些因素或许可以解释饮酒所带来的好处。

专家也警告不要过度引申研究结果:我们必须意识到我们仅仅能够探索酒精摄入量与结果的相关性,并不能推断出因果关系。在医学界,进行随机对照试验不太容易,所以我们仅仅根据可测量的结果来得出临床结论。尽管如此,现有研究并没有发现任何证据反对适度饮酒,至少在心血管方面还没有。

原始出处

Blomster JI1, Zoungas S, Chalmers J, Li Q, Chow CK, Woodward M, Mancia G, Poulter N, Williams B, Harrap S, Neal B, Patel A, Hillis GS.The Relationship Between Alcohol Consumption and Vascular Complications and Mortality in Individuals With Type 2 Diabetes Mellitus.Diabetes Care. 2014 Feb 27

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    2015-02-19 智智灵药
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