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Hypertension:诊室外血压对高血压及相关心血管病更具预测价值

2019-09-25 国际循环编辑部 国际循环

高血压及高血压性心脏病的发病率具有显著种族差异。近期发表于Hypertension杂志的一项研究以发病率较高的美国人群为基础展开,评估诊室外血压与临床血压对高血压性心脏病的预测能力。

高血压高血压性心脏病的发病率具有显著种族差异。近期发表于Hypertension杂志的一项研究以发病率较高的美国人群为基础展开,评估诊室外血压与临床血压对高血压性心脏病的预测能力。

这项研究旨在比较非西班牙裔黑人和白人成年人群进行诊室外血压测量和临床血压测量与心脏磁共振成像诊断左室肥厚的相关性。在这项横断面研究中,共纳入Dallas心脏研究中30~64岁的1262例的黑人和927例白人受试者,给予准化临床血压和诊室外血压测量(研究人员获得)血压病评估左心室质量指数。对接受治疗和未接受治疗的受试者进行的多变量校正分析结果显示,诊室外血压比临床血压更能预测左室肥厚[每10 mm Hg的诊室外收缩压OR=1.48(95%CI:1.34~1.64),临床收缩压OR=1.15(95%CI:1.04~1.28);诊室外舒张压OR=1.71(95%CI:1.43~2.05),临床舒张压的OR=1.03(95%CI:0.86~1.24)]。非西班牙裔黑人种族/种族、治疗状态和左室射血分数较低也是肥大的独立决定因素。与接受治疗的白人或未接受治疗的受试者相比,黑人的诊室外血压和临床血压与左心室肥大之间的相关性差异更为显著。

诊室外血压监测可提供单纯临床血压评估无法获得的重要信息。上述研究结果强调诊室外高血压管理项目对预防高血压性心脏病的意义,这一点对某些种族(非西班牙裔黑人)尤为重要。

原始出处:
Florian Rader, Stanley S. Franklin, James Mirocha, et al. Superiority of Out-of-Office Blood Pressure for Predicting Hypertensive Heart Disease in Non-Hispanic Black Adults. Hypertension. 16 Sep 2019.


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    2019-10-02 feather89
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    2019-09-26 最帅小男护

    学习了

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