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BMJ:脊柱竹节样变怎么回事?

2016-10-06 MedSci MedSci原创

男性患者,35岁,因腰痛且越来越严重而就诊。睡觉时患者常因背痛而疼醒。下图是患者的X线片,诊断是什么?诊断:强直性脊柱炎棘间韧带出现弥散性钙化,这种情况称之为“匕首刺”,如下图黑色箭头所示。同时椎体间的韧带弥散性钙化出现典型的“脊柱竹节样变”,如下图白色箭头所示。X线片显示骶髂关节融合。这些表现符合强直性脊柱炎的诊断。强直性脊柱炎是一种炎症性疾病,随着时间的推移,炎症会导致脊柱韧带的钙化和脊柱的融

男性患者,35岁,因腰痛且越来越严重而就诊。睡觉时患者常因背痛而疼醒。下图是患者的X线片,诊断是什么?



诊断:强直性脊柱炎

棘间韧带出现弥散性钙化,这种情况称之为“匕首刺”,如下图黑色箭头所示。同时椎体间的韧带弥散性钙化出现典型的“脊柱竹节样变”,如下图白色箭头所示。X线片显示骶髂关节融合。这些表现符合强直性脊柱炎的诊断。



强直性脊柱炎是一种炎症性疾病,随着时间的推移,炎症会导致脊柱韧带的钙化和脊柱的融合。炎症和融合会导致机体僵硬,灵活性降低,疼痛,以及骨折风险的增加。本病例中患者并没有发生骨折。

单一检测并不能做出诊断,虽然血液测试,如C反应蛋白、红细胞沉降率,以及人类白细胞抗原B27可以帮助诊断。疾病早期脊柱的病变较小,磁共振成像检查有助于诊断的确定。治疗应遵循风湿病的治疗,包括物理疗法和镇痛。有时可使用疾病修饰药物和生物治疗。

原始出处:

Joseph Dalby Sinnott, David C Howlett. A plain radiograph in back pain. BMJ 2016; 355 doi: http://dx.doi.org/10.1136/bmj.i5003.

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    2016-12-15 gaoxiaoe
  2. [GetPortalCommentsPageByObjectIdResponse(id=1848119, encodeId=1e27184811909, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Thu Dec 15 12:21:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161287, encodeId=689816128e2d, content=可惜现在无法根治,希望早日攻克。, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a0481924837, createdName=医者自明, createdTime=Thu Dec 08 21:19:25 CST 2016, time=2016-12-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=145921, encodeId=875e145921fb, content=好文章,受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Oct 11 22:26:06 CST 2016, time=2016-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=142048, encodeId=477014204867, content=很多人患病, beContent=null, objectType=article, channel=null, level=null, likeNumber=1, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yqGyqlRsWYXXlASPpCvDxQIOj4U5ibyTGicNR5nTPxfE7J8CJLYEoTQiax0mdQk45PFsUH94hHxH18w/0, createdBy=96eb98305, createdName=qixiaotong123, createdTime=Sat Oct 08 14:37:34 CST 2016, time=2016-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141506, encodeId=271b141506ef, content=治疗难度很大!很难!, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Fri Oct 07 11:24:41 CST 2016, time=2016-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141505, encodeId=dc0214150535, content=强直性脊柱炎很痛苦!, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Fri Oct 07 11:24:22 CST 2016, time=2016-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141504, encodeId=73e014150459, content=学习了,分享一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Fri Oct 07 11:23:25 CST 2016, time=2016-10-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=141433, encodeId=630a141433d9, content=学习了谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Fri Oct 07 09:15:02 CST 2016, time=2016-10-07, status=1, ipAttribution=)]
    2016-12-08 医者自明

    可惜现在无法根治,希望早日攻克。

    0

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    2016-10-11 1e10c84am36(暂无匿称)

    好文章,受益

    0

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    2016-10-08 qixiaotong123

    很多人患病

    0

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    2016-10-07 1e0d99ddm02(暂无匿称)

    治疗难度很大!很难!

    0

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    2016-10-07 1e0d99ddm02(暂无匿称)

    强直性脊柱炎很痛苦!

    0

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    2016-10-07 1e0d99ddm02(暂无匿称)

    学习了,分享一下!

    0

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    2016-10-07 刘煜

    学习了谢谢。

    0

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