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好牛气!布洛芬可降低吸烟者肺癌的死亡风险

2016-12-15 MedSci MedSci原创

布洛芬是一种常用的药物,可减轻疼痛和炎症,但是来自美国俄亥俄州立大学的一项新的研究表明,布洛芬还可降低吸烟者肺癌的死亡风险,其研究成果已在IASLC第17次WCLC上展示。 已知,吸烟是肺癌发生的一个重要危险因素,既往研究表明,慢性炎症与肺癌的风险增加有关。而布洛芬可减少炎症反应,因此,研究人员开始着手探究布洛芬是否有益于吸烟史的人。 研究人员分析了第三届全国健康和营养调查(NHANE

布洛芬是一种常用的药物,可减轻疼痛和炎症,但是来自美国俄亥俄州立大学的一项新的研究表明,布洛芬还可降低吸烟者肺癌的死亡风险,其研究成果已在IASLC第17次WCLC上展示。

已知,吸烟是肺癌发生的一个重要危险因素,既往研究表明,慢性炎症与肺癌的风险增加有关。而布洛芬可减少炎症反应,因此,研究人员开始着手探究布洛芬是否有益于吸烟史的人。

研究人员分析了第三届全国健康和营养调查(NHANES III,1988-1994)的部分数据,包括10735名参与者。

收集研究基线期受试者的吸烟状况,布洛芬和其他非甾体抗炎药(NSAIDs)的使用,以及其他生活方式因素的信息。

平均随访18年,使用2006年及以前的国家死亡指数的数据来确定病因特异性死亡率的状况。使用Cox比例风险回归模型来估计非甾体类抗炎药的使用与肺癌死亡风险之间的关联。

随访期间,269名参与者死于肺癌,其中252人有吸烟史。

由于绝大多数肺癌病例都是在过去或当前吸烟,此外,研究人员还在另一个5882名存在吸烟史的成人参与者中计算了非甾体类抗炎药的作用。

总体而言,研究小组发现,与不使用布洛芬的(既往)吸烟者相比,经常使用布洛芬的死于肺癌的可能性降低了48%。

但是,研究发现阿司匹林的使用与肺癌死亡风险之间的关联并无统计学意义。

戒烟和采取健康的生活方式仍然是降低肺癌发生风险的最佳方法。但是,该研究结果表明,经常使用布洛芬或有益于部分群体。

原始出处:

Honor Whiteman. Ibuprofen could reduce smokers' risk of death from lung cancer. MNT, 12 December 2016.


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    2016-12-17 母鸡

    很好学习并分享了布洛芬的新资讯

    0

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    2016-12-16 母鸡

    很好学习并分享了

    0

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    2016-12-16 1e0f8808m18(暂无匿称)

    还是戒烟为最好的预防肺癌方法。

    0

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    2016-12-15 1e1966c3m89(暂无匿称)

    有待进一步研究

    0

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    2016-12-15 jetleo

    研究小组发现,与不使用布洛芬的(既往)吸烟者相比,经常使用布洛芬的死于肺癌的可能性降低了48%。

    0

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    2016-12-15 flysky120

    布洛芬以后注意

    0

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    2016-12-15 huangwukui

    厉害,耳目一新

    0

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    2016-12-15 huangwukui

    厉害

    0

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