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Pediatrics:新生儿出院前进行彻底的风险评估非常重要

2015-11-30 徐媛 MedSci原创

在出新生儿出院之前,应该对可能发生的严重高胆红素血症的危险因素进行评估。研究人员确定了足月儿的高胆红素血(妊娠年龄≥37周)相关风险因素以及对母亲和围产期相关风险因素进行了分析,进而形成一个个性化的临床使用的风险评估工具。 本研究以人群为基础,收纳了来自于1999年到2012年瑞典医出生登记的数据,共收纳了1261948名新生儿。其中23711名新生儿被诊断为高胆红素血症,排除溶血性疾病的新生儿

在出新生儿出院之前,应该对可能发生的严重高胆红素血症的危险因素进行评估。研究人员确定了足月儿的高胆红素血(妊娠年龄≥37周)相关风险因素以及对母亲和围产期相关风险因素进行了分析,进而形成一个个性化的临床使用的风险评估工具。

本研究以人群为基础,收纳了来自于1999年到2012年瑞典医出生登记的数据,共收纳了1261948名新生儿。其中23711名新生儿被诊断为高胆红素血症,排除溶血性疾病的新生儿,对非溶血性黄疸的危险因素进行预测。

新生儿高胆红素血≥1.5(中型效应或更多)的风险因素有妊娠年龄37-38周(调整优势比aOR = 2.83),亚裔母亲(优势比= 2.09),初产妇(aOR = 2.06),胎龄较大的婴儿(优势比=1.84),母亲超重或肥胖(优势比=1.83),胎龄较小的婴儿(优势比= 1.66)。剖宫产风险降低(aOR = 0.45)。而在适于胎龄儿、无引产的阴道分娩、胎龄39~41周出生,非亚裔、非肥胖的经产母亲,新生儿非溶血性高胆红素血症的发生率仅为0.7%。与不同风险因素相比,新生儿发生高胆红素血的风险比例在0.2%到25%不等。

在对新生儿出院前进行胆红素水平的风险评估中,收集母亲及孕产期相关信息非常重要。较高的胆红素水平可能引起的脑神经系统的损害。因此,在所有新生儿出院前进行彻底的风险评估显得极其重要。

原始出处

Norman M1, ?berg K2, Holmsten K3, Weibel V4, Ekéus C2.Predicting Nonhemolytic Neonatal Hyperbilirubinemia.Pediatrics. 2015 Nov 9.

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    2016-02-21 智智灵药
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    2016-09-05 hbwxf
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    2015-12-01 dearluodi

    有意思

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1769938, encodeId=838e1e699386a, content=<a href='/topic/show?id=51469830949' target=_blank style='color:#2F92EE;'>#院前#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98309, encryptionId=51469830949, topicName=院前)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c5ca38130612, createdName=mhzhuang@stu.e, createdTime=Tue Feb 16 13:19:00 CST 2016, time=2016-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725948, encodeId=54781e25948d4, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sun Feb 21 18:19:00 CST 2016, time=2016-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637221, encodeId=3305163e22111, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Sun May 01 02:19:00 CST 2016, time=2016-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1958437, encodeId=5acd195843ed0, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Mon Sep 05 09:19:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44234, encodeId=2d754423473, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=196, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3601615208, createdName=dearluodi, createdTime=Tue Dec 01 01:34:00 CST 2015, time=2015-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=44198, encodeId=17984419802, content=形成出院常规呗, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Mon Nov 30 18:18:00 CST 2015, time=2015-11-30, status=1, ipAttribution=)]
    2015-11-30 lyh994

    形成出院常规呗

    0

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