Circulation：慢性肾病与心脏疾病密切相关，增加了心血管疾病患者的不良预后风险！

2017-07-31 MedSci MedSci原创

慢性肾病(CKD)被认为是全球公共卫生问题。最新的国际临床指南强调肾小球滤过率(GFR)和蛋白尿。CKD与心脏疾病密切相关，增加心血管疾病(CVD)患者的不良预后风险。事实上，大量的研究已经研究了CKD预后与心血管病患者的关系，但大多数研究都集中在肾功能上，对蛋白尿研究的数据有限。

慢性肾病(CKD)被认为是全球公共卫生问题。最新的国际临床指南强调肾小球滤过率(GFR)和蛋白尿。CKD与心脏疾病密切相关，增加心血管疾病(CVD)患者的不良预后风险。事实上，大量的研究已经研究了CKD预后与心血管病患者的关系，但大多数研究都集中在肾功能上，对蛋白尿研究的数据有限。

因此，虽然有一些针对CVD合并肾功能的风险预测工具，但没有一项研究包括蛋白尿。此外，在这些工具中，肾功能指标的选择(如：血清肌酐，基于肌酐的GFR估计值，或血尿素氮都是异质性的。基于目前的研究文献，研究文章总结了这些方面以及CVD患者的CKD负担。研究人员还讨论了将CKD与次要事件联系起来的潜在机制，并考虑未来的研究方向。鉴于其临床和公共卫生的重要性，对于心血管疾病，研究人员着重于两种有代表性的心脏疾病：心肌梗死和心衰。

研究显示：肾功能减少在MI或HF患者中非常普遍，是这些临床人群预后不良的强有力预测因子。尽管国际建议通过测量GFR和蛋白尿来描述CKD，但关于蛋白尿的1个数据仍然是有限的，这保证了对心脏疾病(尤其是MI)患者的负担和预后影响的未来的研究。由此可见，对于MI或HF患者，医务人员不仅要注意肾功能减少，而且要关注蛋白尿症。

原始出处：

Yejin Mok，Shoshana H. Ballew，Kunihiro Matsushita, et al. Prognostic Value of Chronic Kidney Disease Measures in Patients With Cardiac Disease. Circulation. 2017 July.

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2018-05-12 hmwwww

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2017-08-02 12498e0fm78暂无昵称

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2017-08-02 andy2090

#血管疾病#

51 0
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2017-08-01 1ddf0692m34(暂无匿称)

学习了，涨知识

114 0
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2017-08-01 QFXL123456

以后多关注心脑血管患者的蛋白尿，学习了

134 0
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2017-08-01 flysky120

学习一下知识

122 0

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Circulation：慢性肾病与心脏疾病密切相关，增加了心血管疾病患者的不良预后风险！

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