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EuroIntervention:意大利研究称,近端脑保护装置下颈动脉支架成形术后肾损伤发生率高

2018-04-16 xujing 中国循环杂志

意大利学者研究发现,近端脑保护装置下颈动脉支架成形术(CAS)后肾损伤发生率高达34%。

意大利学者研究发现,近端脑保护装置下颈动脉支架成形术(CAS)后肾损伤发生率高达34%。

本研究中,急性肾损伤的定义为术后48小时内血清肌酐增加>0.3 mg/dl或至少增加至基线水平的1.5倍。

研究人员称,高血压糖尿病、血脂异常、贫血和基线肾功能下降的患者易发生术后急性肾损伤。

而且,与未发生急性肾损害的患者相比,发生急性肾损伤的患者的对比剂体积与肌酐清除率的比值更高(2.4 vs 2.08),术后平均动脉压低(94.3 vs 99.6),多会发生收缩压下降50 mmHg以上(23.9% vs 14.3%)。

研究者进一步分析发现,收缩压至少降低50 mmHg(OR= 1.97)、糖尿病(OR=1.64)和血脂异常(OR=1.77)是急性肾损伤的独立危险因素。

研究纳入456例接受近端保护的CAS患者。

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    2018-04-18 hittouch
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    2018-04-16 1e17414fm02(暂无匿称)

    学习

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