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Sci Rep:成年男性中不同水平的雌二醇水平与性功能障碍有关

2020-08-18 AlexYang MedSci原创

射精功能障碍,包括早泄(PE)和延迟射精(DE)以及勃起功能障碍(ED),这些是男性性功能障碍的主要部分。尽管有相当的数据阐释了激素的作用,勃起以及射精,但由于目前目前的文献研究结果存在矛盾,因此没有

射精功能障碍,包括早泄(PE)和延迟射精(DE)以及勃起功能障碍(ED),这些是男性性功能障碍的主要部分。尽管有相当的数据阐释了激素的作用,勃起以及射精,但由于目前目前的文献研究结果存在矛盾,因此没有确切的定论。

最近,有研究人员探索了男性性功能障碍与激素情况之间的关系。研究是要给回顾性的案例-对照研究,包括了1076名年龄在16-60岁的男性(平均年龄:32.12岁);507名被分类为ED、PE和DE组。569没有性功能障碍的男性作为对照组。研究人员收集和分析了他们的背景特征和临床特性。研究发现,ED组中,雌二醇的水平值与对照组相比显著提高(109.44±47.14 pmol/L vs. 91.88±27.68 pmol/L; P<0.001)。与之相反,DE组比对照组具有显著更低水平的雌二醇水平(70.76±27.20 pmol/L vs. 91.88±27.68 pmol/L; P<0.001)。另外,PE组与对照组相比,具有相似水平的雌二醇水平(91.73±31.57 pmol/L vs. 91.88±27.68 pmol/L; P=0.960),但具有显著更高的睾丸酮水平(17.23±5.72 nmol/L vs. 15.31±4.31 nmol/L; P<0.001)。

不同组之间的激素情况

不同变量评估的ED,PE和DE风险情况

最后,研究人员指出,血清睾酮浓度的提高是PE的一个独立风险因素。另外,从DE组、PE组到ED组,其雌二醇值呈逐步递增的梯度分布。

原始出处:

Tong Chen, Fei Wu, Xianlong Wang et al. Different levels of estradiol are correlated with sexual dysfunction in adult men. Sci Rep. 29 July 2020

 

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    2020-11-02 lichifeng

    获益

    0

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    2020-08-20 ms3000000449926787

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=896162, encodeId=570e8961622f, content=获益, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/b1wvblgVe3DzeVwvHZ1RvcUDjV5rdn37aluS21NEb5eH9WE20J7GzMGmZytribqdI1Yz2uSsibpkNVUz608aukFw/132, createdBy=04e95230639, createdName=lichifeng, createdTime=Mon Nov 02 07:55:33 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=811617, encodeId=1e5e81161ecf, content=哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f435296195, createdName=ms3000000449926787, createdTime=Thu Aug 20 23:13:17 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299423, encodeId=6ee1129942376, content=<a href='/topic/show?id=60ea98e5030' target=_blank style='color:#2F92EE;'>#雌二醇#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98750, encryptionId=60ea98e5030, topicName=雌二醇)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4f9e287, createdName=hxzhang, createdTime=Thu Aug 20 04:36:57 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421329, encodeId=b6511421329ea, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Thu Aug 20 04:36:57 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810799, encodeId=abb8810e9930, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:47:46 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810756, encodeId=f379810e568e, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:37:39 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810661, encodeId=c5378106614c, content=论雌二醇水平对男性的重要性。<a href='/topic/show?id=b0b35265484' target=_blank style='color:#2F92EE;'>#性功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52654, encryptionId=b0b35265484, topicName=性功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Aug 19 13:48:28 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810502, encodeId=d63e8105026a, content=<a href='/topic/show?id=b0b35265484' target=_blank style='color:#2F92EE;'>#性功能障碍#</a>不太相信,这个结果,阳痿的病人雄激素和雌激素可能都比较低。, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52654, encryptionId=b0b35265484, topicName=性功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Aug 18 19:37:36 CST 2020, time=2020-08-18, status=1, ipAttribution=)]
    2020-08-19 ms5000000741733160

    👍

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=896162, encodeId=570e8961622f, content=获益, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/b1wvblgVe3DzeVwvHZ1RvcUDjV5rdn37aluS21NEb5eH9WE20J7GzMGmZytribqdI1Yz2uSsibpkNVUz608aukFw/132, createdBy=04e95230639, createdName=lichifeng, createdTime=Mon Nov 02 07:55:33 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=811617, encodeId=1e5e81161ecf, content=哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f435296195, createdName=ms3000000449926787, createdTime=Thu Aug 20 23:13:17 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299423, encodeId=6ee1129942376, content=<a href='/topic/show?id=60ea98e5030' target=_blank style='color:#2F92EE;'>#雌二醇#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98750, encryptionId=60ea98e5030, topicName=雌二醇)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4f9e287, createdName=hxzhang, createdTime=Thu Aug 20 04:36:57 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421329, encodeId=b6511421329ea, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Thu Aug 20 04:36:57 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810799, encodeId=abb8810e9930, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:47:46 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810756, encodeId=f379810e568e, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:37:39 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810661, encodeId=c5378106614c, content=论雌二醇水平对男性的重要性。<a href='/topic/show?id=b0b35265484' target=_blank style='color:#2F92EE;'>#性功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52654, encryptionId=b0b35265484, topicName=性功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Aug 19 13:48:28 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810502, encodeId=d63e8105026a, content=<a href='/topic/show?id=b0b35265484' target=_blank style='color:#2F92EE;'>#性功能障碍#</a>不太相信,这个结果,阳痿的病人雄激素和雌激素可能都比较低。, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52654, encryptionId=b0b35265484, topicName=性功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Aug 18 19:37:36 CST 2020, time=2020-08-18, status=1, ipAttribution=)]
    2020-08-19 ms5000000741733160

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=896162, encodeId=570e8961622f, content=获益, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/b1wvblgVe3DzeVwvHZ1RvcUDjV5rdn37aluS21NEb5eH9WE20J7GzMGmZytribqdI1Yz2uSsibpkNVUz608aukFw/132, createdBy=04e95230639, createdName=lichifeng, createdTime=Mon Nov 02 07:55:33 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=811617, encodeId=1e5e81161ecf, content=哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f435296195, createdName=ms3000000449926787, createdTime=Thu Aug 20 23:13:17 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299423, encodeId=6ee1129942376, content=<a href='/topic/show?id=60ea98e5030' target=_blank style='color:#2F92EE;'>#雌二醇#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98750, encryptionId=60ea98e5030, topicName=雌二醇)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4f9e287, createdName=hxzhang, createdTime=Thu Aug 20 04:36:57 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421329, encodeId=b6511421329ea, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Thu Aug 20 04:36:57 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810799, encodeId=abb8810e9930, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:47:46 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810756, encodeId=f379810e568e, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:37:39 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810661, encodeId=c5378106614c, content=论雌二醇水平对男性的重要性。<a href='/topic/show?id=b0b35265484' target=_blank style='color:#2F92EE;'>#性功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52654, encryptionId=b0b35265484, topicName=性功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Aug 19 13:48:28 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810502, encodeId=d63e8105026a, content=<a href='/topic/show?id=b0b35265484' target=_blank style='color:#2F92EE;'>#性功能障碍#</a>不太相信,这个结果,阳痿的病人雄激素和雌激素可能都比较低。, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52654, encryptionId=b0b35265484, topicName=性功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Aug 18 19:37:36 CST 2020, time=2020-08-18, status=1, ipAttribution=)]
    2020-08-19 Jessica

    论雌二醇水平对男性的重要性。#性功能障碍#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=896162, encodeId=570e8961622f, content=获益, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/b1wvblgVe3DzeVwvHZ1RvcUDjV5rdn37aluS21NEb5eH9WE20J7GzMGmZytribqdI1Yz2uSsibpkNVUz608aukFw/132, createdBy=04e95230639, createdName=lichifeng, createdTime=Mon Nov 02 07:55:33 CST 2020, time=2020-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=811617, encodeId=1e5e81161ecf, content=哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=162, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8f435296195, createdName=ms3000000449926787, createdTime=Thu Aug 20 23:13:17 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299423, encodeId=6ee1129942376, content=<a href='/topic/show?id=60ea98e5030' target=_blank style='color:#2F92EE;'>#雌二醇#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98750, encryptionId=60ea98e5030, topicName=雌二醇)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4f9e287, createdName=hxzhang, createdTime=Thu Aug 20 04:36:57 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421329, encodeId=b6511421329ea, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Thu Aug 20 04:36:57 CST 2020, time=2020-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810799, encodeId=abb8810e9930, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=134, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:47:46 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810756, encodeId=f379810e568e, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:37:39 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810661, encodeId=c5378106614c, content=论雌二醇水平对男性的重要性。<a href='/topic/show?id=b0b35265484' target=_blank style='color:#2F92EE;'>#性功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52654, encryptionId=b0b35265484, topicName=性功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Wed Aug 19 13:48:28 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810502, encodeId=d63e8105026a, content=<a href='/topic/show?id=b0b35265484' target=_blank style='color:#2F92EE;'>#性功能障碍#</a>不太相信,这个结果,阳痿的病人雄激素和雌激素可能都比较低。, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52654, encryptionId=b0b35265484, topicName=性功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=lovetcm, createdTime=Tue Aug 18 19:37:36 CST 2020, time=2020-08-18, status=1, ipAttribution=)]
    2020-08-18 lovetcm

    #性功能障碍#不太相信,这个结果,阳痿的病人雄激素和雌激素可能都比较低。

    0

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