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EULAR 2016:积极的态度可提高风湿性关节炎患者的依从性

2016-06-13 Emma 来宝网

近日欧洲抗风湿联盟年会(European League Against Rheumatism Annual Congress,EULAR 2016)上的两项研究解释了为何很多风湿性关节炎(Rheumatoid Arthritis,RA)患者依从性不好,即使是治疗的早期阶段,患者不遵医嘱也是常见的事情。这两项研究的要点为:(1)与那些更少地自主搜寻相关信息和对疾病有消极态度的人相比,那些会自主搜寻相

近日欧洲抗风湿联盟年会(European League Against Rheumatism Annual Congress,EULAR 2016)上的两项研究解释了为何很多风湿性关节炎(Rheumatoid Arthritis,RA)患者依从性不好,即使是治疗的早期阶段,患者不遵医嘱也是常见的事情。

这两项研究的要点为:(1)与那些更少地自主搜寻相关信息和对疾病有消极态度的人相比,那些会自主搜寻相关信息并对疾病保持积极期望的患者更有可能有很好的依从性。(2)患者在开始甲氨蝶呤治疗时出现焦虑的情况往往意味着患者在治疗的前6个月无效,这很可能与患者很差的依从性有关。

为了找出早期风湿性关节炎患者在治疗早期依从性较差的风险因素,研究者纳入了259例近期被诊断为风湿性关节炎的患者,并对患者开展抗风湿的治疗。研究者对患者进行随访,并评估患者的依从性。

研究者发现,这些患者刚开始的依从性很高,但是在开始治疗的3个月里,依从性迅速下降。在15个可能影响依从性的因素中,“搜寻信息”和“对疾病的积极态度”与患者的依从性显著相关。

与患者依从性不相关的因素有抑郁、消极情绪、非特异性的焦虑、残疾、对治疗必要性和不良反应的认知等。

该研究的主要作者Suzan Verstappen医生说道,患者开始甲氨蝶呤治疗时感到焦虑会导致患者的依从性下降,如果能够预测哪些患者的依从性会较差,我们可以提早干预,或者提供其他治疗药物。


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    2016-06-15 lmm397
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    2016-06-15 fyxzlh
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    2016-06-15 muzishouyi
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