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JACC:未经治疗的中重度主动脉瓣狭窄患者远期生存率低

2019-10-18 不详 MedSci原创

历史数据显示未接受治疗的主动脉瓣狭窄(AS)患者的生存率低主要局限于严重AS患者。本研究的目的旨在评估所有AS类型患者的预后。本研究纳入分析了测量过主动脉瓣流速和压差的122809名男性患者(平均年龄61±17岁)和118494名女性患者(62±19岁),并排除之前接受过主动脉瓣干预治疗的患者。最终,共有16129名患者(6.7%)、3315名(1.4%)和6383名(2.6%)患者分别为轻度、中

历史数据显示未接受治疗的主动脉瓣狭窄(AS)患者的生存率低主要局限于严重AS患者。本研究的目的旨在评估所有AS类型患者的预后。

本研究纳入分析了测量过主动脉瓣流速和压差的122809名男性患者(平均年龄61±17岁)和118494名女性患者(62±19岁),并排除之前接受过主动脉瓣干预治疗的患者。最终,共有16129名患者(6.7%)、3315名(1.4%)和6383名(2.6%)患者分别为轻度、中度和重度AS。经过平均1208天时间的随访,与无AS患者相比,轻中度AS患者的远期生存率明显更低(HR: 1.44-2.09; p < 0.001),中度和重度AS患者的5年死亡率分别是56%和67%。另外,平均主动脉压差>20mmHg患者的全因和心血管死亡风险明显升高。

研究结果显示,未经治疗的重度AS患者远期生存率明显更低,中度AS患者也较低。

原始出处:

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    2020-04-17 hbwxf
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