Baidu
map

Allergy:母乳喂养与儿童哮喘相关性研究

2017-04-29 MedSci MedSci原创

一些研究提出母乳喂养可能存在免疫调节的作用,可影响儿童变应性致敏和过敏性疾病的发展。2017年4月29日发表在Allergy杂志上的一篇文章就母乳喂养与儿童过敏性疾病、湿疹、哮喘相关性进行了研究。该研究主要研究的是母乳喂养与儿童变应性致敏性疾病、吸入性或食物过敏、湿疹,之间的关系;以及其相关性是否受到环境因素的暴露不同或母体是否既往患有哮喘、过敏症、湿疹的影响。该研究是在以人群为基础的5828名儿

一些研究提出母乳喂养可能存在免疫调节的作用,可影响儿童变应性致敏和过敏性疾病的发展。2017年4月29日发表在Allergy杂志上的一篇文章就母乳喂养与儿童过敏性疾病、湿疹、哮喘相关性进行了研究。

该研究主要研究的是母乳喂养与儿童变应性致敏性疾病、吸入性或食物过敏、湿疹,之间的关系;以及其相关性是否受到环境因素的暴露不同或母体是否既往患有哮喘、过敏症、湿疹的影响。

该研究是在以人群为基础的5828名儿童中进行的前瞻性的队列研究,从胚胎期即开始进行研究。该研究者通过邮政问卷调查来收集信息,调查内容为婴儿期的母乳喂养的持续时间(< 2个月,2 - 4个月,4 - 6个月和≥6个月)和非纯母乳喂养的时间(4个月)。在这些孩子10岁的时候,使用皮肤过敏试验来检测是否吸入性或食物过敏;并邮寄问卷调查是否有医师诊断的吸入剂过敏或食物过敏。父母亲既往有湿疹病史的,在其后代的出生到10岁期间也可能会出现湿疹。

该研究结果提示,并未发现母乳喂养与任何变应性致敏、医师诊断的过敏性疾病、或与其相关的过敏性的结局相关。母乳喂养的时间过短会增加儿童患有湿疹的风险(p-value for trend <0.05)。与前4个月纯母乳喂养的婴儿相比,非纯母乳喂养的儿童其患有湿疹的总体风险增加(aOR (95% CI): 1.11 (1.01, 1.23))。周期特异性风险敏感性分析提示,给2月龄的湿疹患者使用药膏,对比延迟使用者,结果表明暴露因素的不同对预后的影响不明显。研究结果表明,婴儿的过敏、湿疹、哮喘等疾病与母亲的既往史无明确的相关性。

原始出处:

Elbert NJ,van Meel ER,den Dekker HT,et al.Duration and exclusiveness of breastfeeding and risk of childhood atopic diseases.Allergy. 2017 Apr 27. doi: 10.1111/all.13195.

本文系梅斯医学(medsci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1837236, encodeId=6454183e23677, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Tue Jul 18 22:22:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1665009, encodeId=2403166500954, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Tue Jun 13 18:22:00 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295942, encodeId=d28c129594210, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299546, encodeId=bace1299546d4, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1328936, encodeId=fc22132893651, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1837236, encodeId=6454183e23677, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Tue Jul 18 22:22:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1665009, encodeId=2403166500954, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Tue Jun 13 18:22:00 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295942, encodeId=d28c129594210, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299546, encodeId=bace1299546d4, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1328936, encodeId=fc22132893651, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1837236, encodeId=6454183e23677, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Tue Jul 18 22:22:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1665009, encodeId=2403166500954, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Tue Jun 13 18:22:00 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295942, encodeId=d28c129594210, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299546, encodeId=bace1299546d4, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1328936, encodeId=fc22132893651, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1837236, encodeId=6454183e23677, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Tue Jul 18 22:22:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1665009, encodeId=2403166500954, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Tue Jun 13 18:22:00 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295942, encodeId=d28c129594210, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299546, encodeId=bace1299546d4, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1328936, encodeId=fc22132893651, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
    2017-05-01 仁医06
  5. [GetPortalCommentsPageByObjectIdResponse(id=1837236, encodeId=6454183e23677, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Tue Jul 18 22:22:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1665009, encodeId=2403166500954, content=<a href='/topic/show?id=c8664008e1a' target=_blank style='color:#2F92EE;'>#喂养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40087, encryptionId=c8664008e1a, topicName=喂养)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0ed425881542, createdName=ms1948154235210413, createdTime=Tue Jun 13 18:22:00 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1295942, encodeId=d28c129594210, content=<a href='/topic/show?id=5d41282361d' target=_blank style='color:#2F92EE;'>#儿童哮喘#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28236, encryptionId=5d41282361d, topicName=儿童哮喘)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1299546, encodeId=bace1299546d4, content=<a href='/topic/show?id=7a056349485' target=_blank style='color:#2F92EE;'>#母乳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63494, encryptionId=7a056349485, topicName=母乳)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1328936, encodeId=fc22132893651, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Mon May 01 04:22:00 CST 2017, time=2017-05-01, status=1, ipAttribution=)]
    2017-05-01 膀胱癌

相关资讯

Pediatrics:母乳喂养对提高认知能力有益吗?

尽管以前的研究表明,母乳喂养对儿童的智力有积极的影响——研究人员说,这可能是因为母乳中的营养成分——现在一项新的研究表明,母乳喂养没有长期的对认知能力的益处。

Cell Chem Biol:研究揭示肠道有益菌群如何适应母乳

母乳为宝宝提供了主要营养元素,同时也有益于寄生在婴儿胃肠道中的微生物。近日,刊登于《细胞—化学生物学》期刊上的研究显示,长双歧杆菌能通过产生一种名为LnbX的酶,成功适应婴儿肠道环境。这一机制使得该细菌能以仅在人奶中富含的糖类为食。

GUT:母乳的成分竟然可以预测早产儿发生坏死性小肠结肠炎!

坏死性小肠结肠炎(NEC)是早产儿中最常见且致命的肠道疾病之一。目前用于识别高危婴儿的标志物以及预防和治疗NEC的疗法是有限的。母乳喂养的NEC发病率明显低于配方喂养婴儿的发病率。婴幼儿配方奶中缺乏人乳寡糖(HMO),如二唾液酸乳酸-N-四糖(DSLNT),其可阻止新生大鼠的NEC。但是,DSLNT是否也能保护人类早产儿发生NEC至今尚未可知。近期,发表在杂志GUT上的文章进行了一项多中心临床队列

母乳喂养,你说不知道的好处!

母乳为刚出生的孩子提供了几乎所有的营养物质,但是不少人或许并不知道,母乳喂养对于初为人母的妈妈,同样有一些好处。母乳是孩子来到世界上得到的第一份礼物,并将伴随着这份礼物度过他最初的时光。那么,这份礼物究竟价值几何呢?事实上,母乳喂养的意义不仅仅在于对孩子的益处,对于母亲,同样有着许多的好处。今天是全国母乳喂养宣传日,母乳喂养的好处之多,确实值得一再宣传。今天小编将盘点母乳喂养的诸多益处!1,可

Allergy:母乳喂养与哮喘的发生相关?

近期杂志上发表的一篇文章中指出,孕产妇母乳脂肪酸成分与儿童喘息或哮喘并不存在相关性。先前的一些观察性研究指出,在母乳喂养的婴幼儿中,母乳脂肪酸成分是导致过敏性湿疹及特异性过敏的重要因素。然而,之后的调查研究发现,学龄期儿童的喘息或哮喘是十分罕见的。该研究使用了一项新的统计方法,针对13岁以下的儿童进行了一项有关母乳脂肪酸成分与喘息或哮喘相关项的调查研究。该研究分别收集产后后6周(n=720)和6个

Biochim Biophys Acta:母乳也成抗癌利器?新研究开启乳铁蛋白“杀手”模式

在一项由奥地利科学基金(FWF)资助的项目中,奥地利格拉茨大学的科学家们对母乳中的某种宿主防御肽进行了改造,使其能够特异性识别并攻击癌细胞。这种存在于多种哺乳动物母乳中的活性大分子可以诱导细胞凋亡,具有潜在的癌症治疗价值。

Baidu
map
Baidu
map
Baidu
map