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Sci Rep:电子烟和非电子烟使用者尿液中膀胱癌致癌物质比较

2018-01-26 AlexYang MedSci原创

电子烟(EC)的使用的流行度越来越高,并且可以作为传统抽烟的替代品,原因是人们认为电子烟是一种更为安全的选择。与使用者认为ECs代表没有风险的观念不同,研究人员的起始研究阐释了电子烟液体中复杂的物质组成。传统的抽烟已被人们认识是膀胱癌发展的风险因子,并且先前的研究报道提醒了人们电子烟液体或者蒸汽中也许包括了那些引起膀胱癌发展的复合物。研究人员从13名电子烟使用者和10名非电子烟使用者中搜集了尿液样

电子烟(EC)的使用的流行度越来越高,并且可以作为传统抽烟的替代品,原因是人们认为电子烟是一种更为安全的选择。与使用者认为ECs代表没有风险的观念不同,研究人员的起始研究阐释了电子烟液体中复杂的物质组成。传统的抽烟已被人们认识是膀胱癌发展的风险因子,并且先前的研究报道提醒了人们电子烟液体或者蒸汽中也许包括了那些引起膀胱癌发展的复合物。

研究人员从13名电子烟使用者和10名非电子烟使用者中搜集了尿液样本。研究人员利用液相色谱-质谱分析(LC-MS)进行了物质组成分析,并且认为5种已知的存在于传统烟叶、燃烧产物或者溶剂中的膀胱癌致癌物在电子烟生产中存在使用情况。通过对电子烟使用者尿液的分析发现,2中致癌复合物,邻甲苯胺和萘胺的浓度分别高出2.3倍和1.3倍(p值分别为0.0013和0.014)。这些受试者(9/13)中的大部分为长期的非抽烟者(大于12个月)。在更高浓度电子烟使用者尿液中的致癌芳香胺情况下,进一步的研究是需要的,从而来确定电子烟的安全情况以及电子烟对膀胱癌发展的贡献情况。

原始出处:

Thomas W. Fuller, Abhinav P. Acharya, Thiagarajan Meyyappan et al. Comparison of Bladder Carcinogens in the Urine of E-cigarette Users Versus Non E-cigarette Using Controls. Sci Rep. 11 Jan 2018.

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    2018-02-02 David201514

    电子烟更有害啊

    0

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    2018-01-28 hb2008ye
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    2018-01-28 qjddjq
  5. [GetPortalCommentsPageByObjectIdResponse(id=2075820, encodeId=2a6b20e5820dd, content=<a href='/topic/show?id=8e448651214' target=_blank style='color:#2F92EE;'>#致癌物质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86512, encryptionId=8e448651214, topicName=致癌物质)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec25412, createdName=yangpeizhi, createdTime=Mon Jan 07 21:48:00 CST 2019, time=2019-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284508, encodeId=bf672845085f, content=电子烟更有害啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2020/02/10/873424c7509107856f96be26c270e89f.jpg, createdBy=0c9b1935072, createdName=David201514, createdTime=Fri Feb 02 18:08:28 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1370930, encodeId=29c713e0930b7, content=<a href='/topic/show?id=9c39864991e' target=_blank style='color:#2F92EE;'>#致癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86499, encryptionId=9c39864991e, topicName=致癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sun Jan 28 11:48:00 CST 2018, time=2018-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1448827, encodeId=0b50144882ea9, content=<a href='/topic/show?id=8dde8651197' target=_blank style='color:#2F92EE;'>#致癌物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86511, encryptionId=8dde8651197, topicName=致癌物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3005440223, createdName=qjddjq, createdTime=Sun Jan 28 11:48:00 CST 2018, time=2018-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1449349, encodeId=978a144934960, content=<a href='/topic/show?id=b3e24e442bc' target=_blank style='color:#2F92EE;'>#尿液#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=94, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47442, encryptionId=b3e24e442bc, topicName=尿液)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66095470791, createdName=zhaohui6733, createdTime=Sun Jan 28 11:48:00 CST 2018, time=2018-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=282290, encodeId=49d2282290de, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Fri Jan 26 21:29:17 CST 2018, time=2018-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=282285, encodeId=7846282285a2, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Fri Jan 26 21:17:31 CST 2018, time=2018-01-26, status=1, ipAttribution=)]
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    2018-01-26 changjiu

    学习一下谢谢

    0

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    2018-01-26 戒馋,懒,贪

    谢谢分享学习了

    0

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