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JACC:高敏肌钙蛋白的引入对心梗的发病率和预后结局的影响

2018-06-06 MedSci MedSci原创

本研究的目的旨在评估自从引入高敏心脏肌钙蛋白T(hs-cTnT)后,对首次心梗的诊断率和预后带来了什么影响。本研究纳入了87879例2009至2013年来自瑞典国家数据库中的所有首发心梗的患者,在研究期间,通过心脏肌钙蛋白诊断出的心梗患者为47133例,而通过hs-cTnT诊断出的心梗患者为40746例,从引入hs-cTnT后,心梗的发病率增加了5%(95% CI: 0%-10%),经过平均3.9

本研究的目的旨在评估自从引入高敏心脏肌钙蛋白T(hs-cTnT)后,对首次心梗的诊断率和预后带来了什么影响。

本研究纳入了87879例2009至2013年来自瑞典国家数据库中的所有首发心梗的患者,在研究期间,通过心脏肌钙蛋白诊断出的心梗患者为47133例,而通过hs-cTnT诊断出的心梗患者为40746例,从引入hs-cTnT后,心梗的发病率增加了5%(95% CI: 0%-10%),经过平均3.9 ± 2.8年时间的随访,共有33492名患者死亡,全因死亡率无明显差异(HR: 1.00; 95% CI: 0.97-1.02)。随访期间,共有15766例再梗死事件发生,通过hs-cTnT诊断的心梗患者的再梗死率减少了11%(HR: 0.89; 95% CI: 0.86-0.91)。此外,hs-cTnT诊断的患者的冠脉造影和血管再生的比率更高。

研究结果显示,自从引入高敏心脏肌钙蛋白T诊断心梗后,心梗的发病率增高但对生存率无明显影响,且患者再梗死率下降但冠脉造影比率更高。

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1823466, encodeId=a969182346671, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Fri Jan 11 16:04:00 CST 2019, time=2019-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1854052, encodeId=ca751854052ed, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Jan 05 22:04:00 CST 2019, time=2019-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322563, encodeId=548232256341, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Jun 08 16:44:26 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325854, encodeId=82711325854b6, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Jun 08 02:04:00 CST 2018, time=2018-06-08, status=1, ipAttribution=)]
    2019-01-05 hbwxf
  3. [GetPortalCommentsPageByObjectIdResponse(id=1823466, encodeId=a969182346671, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Fri Jan 11 16:04:00 CST 2019, time=2019-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1854052, encodeId=ca751854052ed, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Sat Jan 05 22:04:00 CST 2019, time=2019-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322563, encodeId=548232256341, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Jun 08 16:44:26 CST 2018, time=2018-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325854, encodeId=82711325854b6, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Jun 08 02:04:00 CST 2018, time=2018-06-08, status=1, ipAttribution=)]
    2018-06-08 虈亣靌

    了解一下.谢谢分享!

    0

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