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J Periodontol:使用聚丙交酯 - 共 - 乙交酯涂层的β-磷酸三钙骨移植修复颊骨缺损的拔牙窝

2019-03-04 不详 网络

拔牙后牙槽嵴的高度和宽度明显减小。本研究旨在比较评估涂有聚丙交酯-共-乙交酯(β-TCP /PLGA)和常规颗粒β-TCP的β-磷酸三钙在拔牙窝颊骨缺损中的位点保存的效果。在六只小猎犬中,去除其颊骨板后提取上颌第一前磨牙。在抽取插口的位置产生标准化的骨缺损(4 [近中远端宽度]×4 [buccopalatal宽度]×5 [深度] mm)并填充β-TCP / PLGA(测试部位)或颗粒β-TCP(对

拔牙后牙槽嵴的高度和宽度明显减小。本研究旨在比较评估涂有聚丙交酯-共-乙交酯(β-TCP /PLGA)和常规颗粒β-TCP的β-磷酸三钙在拔牙窝颊骨缺损中的位点保存的效果。

在六只小猎犬中,去除其颊骨板后提取上颌第一前磨牙。在抽取插口的位置产生标准化的骨缺损(4 [近中远端宽度]×4 [buccopalatal宽度]×5 [深度] mm)并填充β-TCP / PLGA(测试部位)或颗粒β-TCP(对照部位) )。手术后12周进行微计算机断层扫描,组织学组织学评估。

结果,试验部位的骨量明显大于对照部位(25.7±2.14对16.0±3.3 mm3),但骨材料密度无统计学差异(分别为746.3±23.9 vs. 714.5±37.0 g / cm3)。相对于对照部位,测试部位表现出明显更大的牙槽嵴冠状面(2.0±0.4对1.1±0.3 mm)和中间(2.9±0.2对2.1±0.3 mm)水平宽度和编织骨比例(50.3± 8.1%对38.0±5.2%)和骨髓(17.7±6.6%对比9.7±4.1%),但结缔组织比例明显较低(10.7±4.5%对18.3±5.7%)。

总之,在本研究的限制范围内,可模塑的β-TCP/PLGA移植物似乎比常规的颗粒β-TCP移植物具有更大的潜力,用于保存颊骨缺陷的拔牙窝的牙槽嵴。

原始出处:

Okada M, Matsuura T, et al., Ridge preservation of extraction sockets with buccal bone deficiency using poly lactide-co-glycolide coated beta-tricalcium phosphate bone grafts: An experimental study in dogs. J Periodontol. 2019 Feb 28. doi: 10.1002/JPER.18-0574.

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    2020-02-02 feather89
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    2019-05-22 howi
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    2019-03-06 lfcmxl
  6. [GetPortalCommentsPageByObjectIdResponse(id=1994442, encodeId=32b71994442e0, content=<a href='/topic/show?id=a82156216d3' target=_blank style='color:#2F92EE;'>#拔牙窝#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56216, encryptionId=a82156216d3, topicName=拔牙窝)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=baf586, createdName=wangbingxhy, createdTime=Sun May 12 19:01:00 CST 2019, time=2019-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727915, encodeId=4fba1e27915a5, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Feb 02 02:01:00 CST 2020, time=2020-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1667150, encodeId=7c19166e1506a, content=<a href='/topic/show?id=3dae101809cd' target=_blank style='color:#2F92EE;'>#骨移植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101809, encryptionId=3dae101809cd, topicName=骨移植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bbed26112986, createdName=howi, createdTime=Wed May 22 14:01:00 CST 2019, time=2019-05-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1801448, encodeId=a12a1801448e6, content=<a href='/topic/show?id=b89ae38472d' target=_blank style='color:#2F92EE;'>#磷酸三钙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73847, encryptionId=b89ae38472d, topicName=磷酸三钙)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5b34252, createdName=chenshujs, createdTime=Mon Jul 15 16:01:00 CST 2019, time=2019-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419297, encodeId=8fc0141929eab, content=<a href='/topic/show?id=2e2e10182602' target=_blank style='color:#2F92EE;'>#骨缺损#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101826, encryptionId=2e2e10182602, topicName=骨缺损)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=51173492599, createdName=lfcmxl, createdTime=Wed Mar 06 12:01:00 CST 2019, time=2019-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574235, encodeId=77d515e4235ed, content=<a href='/topic/show?id=36fc56212c6' target=_blank style='color:#2F92EE;'>#拔牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56212, encryptionId=36fc56212c6, topicName=拔牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c5216012416, createdName=xre2013, createdTime=Wed Mar 06 12:01:00 CST 2019, time=2019-03-06, status=1, ipAttribution=)]
    2019-03-06 xre2013
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