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Ann Allergy Asthma Immunol:困扰人们的过敏究竟是哪些因素引起的?

2017-04-13 枫丹白露 来宝网

女皇大学和金斯顿健康科学中心的研究人员发表了来自金士顿过敏出生队列研究的第一组研究结果,该研究追踪了从早产儿到儿童早期的近400对母婴过敏发生的根源。


女皇大学和金斯顿健康科学中心的研究人员发表了来自金士顿过敏出生队列研究的第一组研究结果,该研究追踪了从早产儿到儿童早期的近400对母婴过敏发生的根源。

该研究证实了一些以前已知的在呼吸道症状发展中发挥作用的因素,并且揭示了空气清新剂与呼吸系统问题之间的新联系。研究人员研究了由父母报告的儿童生命第一年中的呼吸系统症状 - 例如喘息、复发性感染、哮喘药物的使用等,以及在过敏形成中发挥作用的外部和内部因素。

该研究的主要作者即生物医学与分子科学系副教授安妮·埃利斯(Anne Ellis)说:“金士顿过敏出生队列研究组是一个真正的新型实验小组。 “金士顿有一些独特的特征,例如吸烟率高于全国平均水平,城乡人口稀少,社会经济水平很低,所有这些因素使我们能够了解涉及到的致敏因素 ”。

队列研究检查了患者的接触物- 所有可能在患者健康中发挥作用的内部和外部因素的组合。这些包括一般的外部因素(如社会经济状况)、特定的外部因素(如接触香烟烟雾)和内部因素(如年龄,父母的病史)。埃利斯博士和她的团队随后能够确定哪些风险已经彼此显着相关,并且单独控制这些因素来确定哪些相关性可能更有意义。

研究人员揭示了房屋中空气清新剂的存在与呼吸道症状之间先前未知的正相关性,该相关性与其他因素无关。该研究还证实了许多以前已知的暴露因素与发生过敏症状可能性之间的相关性。在怀孕期间接触烟草烟雾会增加出现呼吸道症状的可能性,而出生后因素如母乳喂养、较大的兄弟姐妹的出现或母亲在妊娠时年龄较大等因素与过敏反应相关性不大。

埃利斯博士说,按照该队列追踪的能力——其中被追踪的儿童很多已经3-5岁了,随着时间的推移,能够更好地了解导致过敏产生的因素。有关该队列群体的进一步研究正在进行,主要使用皮肤测试来识别过敏症以及进行家庭内调查。

埃里斯博士解释说:“这是我们对金士顿过敏出生队列参与者的第一个真实反馈。” “有许多其他因素可能会促进过敏的发展。通过我们在队列中使用的方法,我们可以解释促进过敏发展的一般外部因素、特殊外部因素和内部因素,以使我们可以真正显着地减少过敏的发生。”

原始出处:

North ML, Brook JR, Lee EY, et al. The Kingston Allergy Birth Cohort: Exploring parentally reported respiratory outcomes through the lens of the exposome. Ann Allergy Asthma Immunol. 2017 Apr.

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    2017-12-07 skhzy
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    2017-04-16 1e10c84am36(暂无匿称)

    文章很好,值得分享

    0

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    2017-04-15 膀胱癌
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    2017-04-14 九天.

    maek

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1977115, encodeId=ee2419e711534, content=<a href='/topic/show?id=0081289832' target=_blank style='color:#2F92EE;'>#asthma#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2898, encryptionId=0081289832, topicName=asthma)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9b30126, createdName=skhzy, createdTime=Thu Dec 07 14:23:00 CST 2017, time=2017-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711003, encodeId=0f2f1e110034c, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Mon Mar 05 08:23:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187810, encodeId=674d18e810dd, content=文章很好,值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Apr 16 05:31:06 CST 2017, time=2017-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1328932, encodeId=fcd2132893231, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Sat Apr 15 12:23:00 CST 2017, time=2017-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187361, encodeId=d2e218e361cb, content=maek, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/02/48d1fec880a796cc2ad284d7b18e6017.jpg, createdBy=43e51704272, createdName=九天., createdTime=Fri Apr 14 14:07:30 CST 2017, time=2017-04-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=187186, encodeId=627e18e186f6, content=这是一个非常有趣的话题,到底是越干净容易过敏,还是脏一点不容易过敏!, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=张发宝-梅斯医学, createdTime=Thu Apr 13 22:59:26 CST 2017, time=2017-04-13, status=1, ipAttribution=)]
    2017-04-13 张发宝-梅斯医学

    这是一个非常有趣的话题,到底是越干净容易过敏,还是脏一点不容易过敏!

    0

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