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紫外线暴露与男性皮肤黑色素瘤的发病率有关,但与女性无关

2016-10-31 MedSci MedSci原创

据发表于 Journal of the American Academy of Dermatology的一项新的研究结果表明,环境紫外线暴露指数与男性皮肤黑色素瘤的发病率有关,但与女性无关。通过分析紫外线指数与性别及年龄之间的关系,研究人员评估了紫外线辐射是否会影响男性及女性在皮肤黑色素瘤的发病率上的差异。研究人员收集了来自美国、澳大利亚、新西兰和欧洲国家的31个癌症登记处的皮肤黑色素瘤数据和每日

据发表于 Journal of the American Academy of Dermatology的一项新的研究结果表明,环境紫外线暴露指数与男性皮肤黑色素瘤的发病率有关,但与女性无关。

通过分析紫外线指数与性别及年龄之间的关系,研究人员评估了紫外线辐射是否会影响男性及女性在皮肤黑色素瘤的发病率上的差异。研究人员收集了来自美国、澳大利亚、新西兰和欧洲国家的31个癌症登记处的皮肤黑色素瘤数据和每日紫外线指数,然后进行了关联分析,并使用了来自美国42个州的第二个数据集进行验证。

结果发现,女性皮肤黑色素瘤的患病率和紫外线指数水平之间并没有关联。而男性及整体皮肤黑色素瘤的患病率和紫外线指数水平之间存在明显地关联(P = 0.0003)。

研究人员计算了5年年龄相关的黑色素瘤发病率,结果发现,在男性中,紫外线指数关联水平随着年龄的增加而增加(P =0. 006),但在女性中则保持不变。研究人员在美国白人人群中验证了上述发现。

总而言之,该研究发现,环境紫外线照射似乎仅与男性黑色素瘤的发生相关,而与女性无关。

至于此研究中女性皮肤黑色素瘤的患病率和紫外线指数水平之间并没有关联的机制尚不清楚,该研究结果揭示了既往黑色素瘤的发生中被忽视的性别因素,由此或可带来关于黑色素瘤新的性别特异性病因研究,并有助于未来制定有针对性的预防措施。

原始出处:

Liu-Smith F, et al. Sex differences in the association of cutaneous melanoma incidence rates and geographic ultraviolet light exposure. J Am Acad Dermatol. 2016;doi:10.1016/j.jaad.2016.08.027.

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    2017-04-15 sunylz
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    2016-11-11 虈亣靌

    讲的好,学习了

    0

  4. 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GetPortalCommentsPageByObjectIdResponse(id=152670, encodeId=ab381526e07e, content=是的吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Tue Nov 01 12:54:49 CST 2016, time=2016-11-01, status=1, ipAttribution=)]
    2016-11-07 培莉

    有意思哈,期待早日发现原因。

    0

  5. 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objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Nov 02 06:53:02 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152673, encodeId=09cd1526e322, content=有没有对生活习惯进行调查, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM5rqTiaMSVSkFAupcTECOTdcVRmJQXbibJoicv5ibhcpa0vj5MGmac8wlPjuGnJISZGtOnC7rW0gbLuSE7iaEvAn0CC52ZhnRLdxtlQ/0, createdBy=1e291737907, createdName=1df01bccm39(暂无匿称), createdTime=Tue Nov 01 12:56:37 CST 2016, time=2016-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152670, encodeId=ab381526e07e, content=是的吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Tue Nov 01 12:54:49 CST 2016, time=2016-11-01, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1680368, encodeId=0f09168036865, content=<a href='/topic/show?id=9e5c86e0712' target=_blank style='color:#2F92EE;'>#色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86707, encryptionId=9e5c86e0712, topicName=色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=343027846633, createdName=sunylz, createdTime=Sat Apr 15 16:30:00 CST 2017, time=2017-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823296, encodeId=d037182329638, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, 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GetPortalCommentsPageByObjectIdResponse(id=152670, encodeId=ab381526e07e, content=是的吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Tue Nov 01 12:54:49 CST 2016, time=2016-11-01, status=1, ipAttribution=)]
    2016-11-02 jyzxjiangqin

    紫外线暴露与男性皮肤黑色素瘤的发病率有关。

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1680368, encodeId=0f09168036865, content=<a href='/topic/show?id=9e5c86e0712' target=_blank style='color:#2F92EE;'>#色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86707, encryptionId=9e5c86e0712, topicName=色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=343027846633, createdName=sunylz, createdTime=Sat Apr 15 16:30:00 CST 2017, time=2017-04-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823296, encodeId=d037182329638, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, 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09:59:14 CST 2016, time=2016-11-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1564783, encodeId=77da1564e8329, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Wed Nov 02 13:30:00 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1558774, encodeId=a54f1558e74fc, content=<a href='/topic/show?id=e27610332666' target=_blank style='color:#2F92EE;'>#黑色素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103326, encryptionId=e27610332666, topicName=黑色素)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Wed Nov 02 13:30:00 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1436005, encodeId=b9e41436005cf, content=<a href='/topic/show?id=c38de2137e4' target=_blank style='color:#2F92EE;'>#皮肤黑色素瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72137, encryptionId=c38de2137e4, topicName=皮肤黑色素瘤)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed Nov 02 13:30:00 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152809, encodeId=9fea152809f9, content=紫外线暴露与男性皮肤黑色素瘤的发病率有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Nov 02 06:53:02 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152673, encodeId=09cd1526e322, content=有没有对生活习惯进行调查, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM5rqTiaMSVSkFAupcTECOTdcVRmJQXbibJoicv5ibhcpa0vj5MGmac8wlPjuGnJISZGtOnC7rW0gbLuSE7iaEvAn0CC52ZhnRLdxtlQ/0, createdBy=1e291737907, createdName=1df01bccm39(暂无匿称), createdTime=Tue Nov 01 12:56:37 CST 2016, time=2016-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152670, encodeId=ab381526e07e, content=是的吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Tue Nov 01 12:54:49 CST 2016, time=2016-11-01, status=1, ipAttribution=)]
    2016-11-01 1df01bccm39(暂无匿称)

    有没有对生活习惯进行调查

    0

  10. 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attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=150614999302, createdName=cqlidoudou, createdTime=Wed Nov 02 13:30:00 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1436005, encodeId=b9e41436005cf, content=<a href='/topic/show?id=c38de2137e4' target=_blank style='color:#2F92EE;'>#皮肤黑色素瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72137, encryptionId=c38de2137e4, topicName=皮肤黑色素瘤)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Wed Nov 02 13:30:00 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152809, encodeId=9fea152809f9, content=紫外线暴露与男性皮肤黑色素瘤的发病率有关。, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Wed Nov 02 06:53:02 CST 2016, time=2016-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152673, encodeId=09cd1526e322, content=有没有对生活习惯进行调查, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM5rqTiaMSVSkFAupcTECOTdcVRmJQXbibJoicv5ibhcpa0vj5MGmac8wlPjuGnJISZGtOnC7rW0gbLuSE7iaEvAn0CC52ZhnRLdxtlQ/0, createdBy=1e291737907, createdName=1df01bccm39(暂无匿称), createdTime=Tue Nov 01 12:56:37 CST 2016, time=2016-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152670, encodeId=ab381526e07e, content=是的吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Tue Nov 01 12:54:49 CST 2016, time=2016-11-01, status=1, ipAttribution=)]
    2016-11-01 保守主义

    是的吗?

    0

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