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Eiger制药宣布首例患者入组聚乙二醇化干扰素联合Ritonavir-Boosted Lonafarnib的II期LIFT研究

2018-08-07 MedSci MedSci原创

聚乙二醇化干扰素lonafarnib利托那韦
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Eiger制药是一家专注于罕见疾病靶向疗法研发的生物制药公司，Eiger近日宣布第一名患者入组了II期LIFT临床试验，该试验在美国国立卫生研究院（NIH）的国家糖尿病、消化和肾脏疾病研究所（NIDDK）中进行。

Eiger制药是一家专注于罕见疾病靶向疗法研发的生物制药公司，Eiger近日宣布第一名患者入组了II期LIFT临床试验，该试验在美国国立卫生研究院（NIH）的国家糖尿病、消化和肾脏疾病研究所（NIDDK）中进行。LIFT是一项开放标签的II期临床研究，旨在评估聚乙二醇化干扰素λ联合利托那韦（RTV）促进的lonafarnib（LNF）治疗慢性肝炎（HDV）患者的有效性和耐受性。

NIDDK的首席研究员，医学博士Christopher Koh表示：“我们之前已在NIDDK的多项研究中证实，lonafarnib和利托那韦增强的lonafarnib可降低HDV患者的HDV RNA病毒载量”。Eiger正在单独开发基于lonafarnib的治疗方案，并与聚乙二醇化干扰素联合作为治疗HDV的潜在疗法，该计划正在通过国际多中心D-LIVR研究进入第III阶段，计划今年晚些时候开始。Eiger制药首席运营官兼执行医疗官David Apelian博士说：“聚乙二醇化干扰素λ代表了一种可能更好的HDV治疗方案，我们的目标是扩大HDV感染患者未来的治疗选择”。


原始出处：

http://www.firstwordpharma.com/node/1583299#axzz5NCMJrdAy

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createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue Aug 07 22:40:11 CST 2018, time=2018-08-07, status=1, ipAttribution=)]
    2018-08-12 aliceclz

    #TED#

    0

  2. 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createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue Aug 07 22:40:11 CST 2018, time=2018-08-07, status=1, ipAttribution=)]
    2019-04-28 12498c32m68暂无昵称

    #GER#

    0

  3. 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createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue Aug 07 22:40:11 CST 2018, time=2018-08-07, status=1, ipAttribution=)]
    2018-08-25 ms9833124466084992

    #boost#

    0

  4. 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objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23387, encryptionId=536f2338e8d, topicName=乙二醇)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b11f36846752, createdName=weiz, createdTime=Mon Nov 26 07:22:00 CST 2018, time=2018-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2055407, encodeId=321f205540e4c, content=<a href='/topic/show?id=002580e74dd' target=_blank style='color:#2F92EE;'>#聚乙二醇化干扰素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80774, encryptionId=002580e74dd, topicName=聚乙二醇化干扰素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Sat May 04 09:22:00 CST 2019, time=2019-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793390, encodeId=19571e93390f4, content=<a href='/topic/show?id=318915509d6' target=_blank style='color:#2F92EE;'>#ritonavir#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15509, encryptionId=318915509d6, topicName=ritonavir)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Fri Oct 26 07:22:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426358, encodeId=a972142635809, content=<a href='/topic/show?id=032b948ec5' target=_blank style='color:#2F92EE;'>#IgE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9487, encryptionId=032b948ec5, topicName=IgE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cff4064659, createdName=zhenjiu124, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624581, encodeId=e48c162458121, content=<a href='/topic/show?id=3f2d2e7087' target=_blank style='color:#2F92EE;'>#ARNI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2770, encryptionId=3f2d2e7087, topicName=ARNI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f41c20676233, createdName=gongliu, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337167, encodeId=807433e16735, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue Aug 07 22:40:11 CST 2018, time=2018-08-07, status=1, ipAttribution=)]
    2018-11-26 weiz

    #乙二醇#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1702944, encodeId=67f91e0294445, content=<a href='/topic/show?id=72351e25437' target=_blank style='color:#2F92EE;'>#TED#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17254, encryptionId=72351e25437, topicName=TED)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76e230462388, createdName=aliceclz, createdTime=Sun Aug 12 18:22:00 CST 2018, time=2018-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2021635, encodeId=939b202163574, content=<a href='/topic/show?id=31e8e9669d' target=_blank style='color:#2F92EE;'>#GER#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7966, encryptionId=31e8e9669d, topicName=GER)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Sun Apr 28 18:22:00 CST 2019, time=2019-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1780439, encodeId=de511e80439a1, content=<a href='/topic/show?id=4ccb36214c' target=_blank style='color:#2F92EE;'>#boost#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3621, encryptionId=4ccb36214c, topicName=boost)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Aug 25 15:22:00 CST 2018, time=2018-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1755202, encodeId=424d1e55202dd, content=<a href='/topic/show?id=536f2338e8d' target=_blank style='color:#2F92EE;'>#乙二醇#</a>, beContent=null, 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encodeId=19571e93390f4, content=<a href='/topic/show?id=318915509d6' target=_blank style='color:#2F92EE;'>#ritonavir#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15509, encryptionId=318915509d6, topicName=ritonavir)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Fri Oct 26 07:22:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426358, encodeId=a972142635809, content=<a href='/topic/show?id=032b948ec5' target=_blank style='color:#2F92EE;'>#IgE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9487, encryptionId=032b948ec5, topicName=IgE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cff4064659, createdName=zhenjiu124, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624581, encodeId=e48c162458121, content=<a href='/topic/show?id=3f2d2e7087' target=_blank style='color:#2F92EE;'>#ARNI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2770, encryptionId=3f2d2e7087, topicName=ARNI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f41c20676233, createdName=gongliu, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337167, encodeId=807433e16735, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue Aug 07 22:40:11 CST 2018, time=2018-08-07, status=1, ipAttribution=)]
    2019-05-04 showtest

    #聚乙二醇化干扰素#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1702944, encodeId=67f91e0294445, content=<a href='/topic/show?id=72351e25437' target=_blank style='color:#2F92EE;'>#TED#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17254, encryptionId=72351e25437, topicName=TED)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76e230462388, createdName=aliceclz, createdTime=Sun Aug 12 18:22:00 CST 2018, time=2018-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2021635, encodeId=939b202163574, content=<a href='/topic/show?id=31e8e9669d' target=_blank style='color:#2F92EE;'>#GER#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7966, encryptionId=31e8e9669d, topicName=GER)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Sun Apr 28 18:22:00 CST 2019, time=2019-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1780439, encodeId=de511e80439a1, content=<a href='/topic/show?id=4ccb36214c' target=_blank style='color:#2F92EE;'>#boost#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3621, encryptionId=4ccb36214c, topicName=boost)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Aug 25 15:22:00 CST 2018, time=2018-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1755202, encodeId=424d1e55202dd, content=<a href='/topic/show?id=536f2338e8d' target=_blank style='color:#2F92EE;'>#乙二醇#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23387, encryptionId=536f2338e8d, topicName=乙二醇)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b11f36846752, createdName=weiz, createdTime=Mon Nov 26 07:22:00 CST 2018, time=2018-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2055407, encodeId=321f205540e4c, content=<a href='/topic/show?id=002580e74dd' target=_blank style='color:#2F92EE;'>#聚乙二醇化干扰素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80774, encryptionId=002580e74dd, topicName=聚乙二醇化干扰素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Sat May 04 09:22:00 CST 2019, time=2019-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793390, encodeId=19571e93390f4, content=<a href='/topic/show?id=318915509d6' target=_blank style='color:#2F92EE;'>#ritonavir#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15509, encryptionId=318915509d6, topicName=ritonavir)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Fri Oct 26 07:22:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426358, encodeId=a972142635809, content=<a href='/topic/show?id=032b948ec5' target=_blank style='color:#2F92EE;'>#IgE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9487, encryptionId=032b948ec5, topicName=IgE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cff4064659, createdName=zhenjiu124, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624581, encodeId=e48c162458121, content=<a href='/topic/show?id=3f2d2e7087' target=_blank style='color:#2F92EE;'>#ARNI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2770, encryptionId=3f2d2e7087, topicName=ARNI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f41c20676233, createdName=gongliu, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337167, encodeId=807433e16735, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue Aug 07 22:40:11 CST 2018, time=2018-08-07, status=1, ipAttribution=)]
    2018-10-26 41514487@qq.com

    #ritonavir#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1702944, encodeId=67f91e0294445, content=<a href='/topic/show?id=72351e25437' target=_blank style='color:#2F92EE;'>#TED#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17254, encryptionId=72351e25437, topicName=TED)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76e230462388, createdName=aliceclz, createdTime=Sun Aug 12 18:22:00 CST 2018, time=2018-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2021635, encodeId=939b202163574, content=<a href='/topic/show?id=31e8e9669d' target=_blank style='color:#2F92EE;'>#GER#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7966, encryptionId=31e8e9669d, topicName=GER)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Sun Apr 28 18:22:00 CST 2019, time=2019-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1780439, encodeId=de511e80439a1, content=<a href='/topic/show?id=4ccb36214c' target=_blank style='color:#2F92EE;'>#boost#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3621, encryptionId=4ccb36214c, topicName=boost)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Aug 25 15:22:00 CST 2018, time=2018-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1755202, encodeId=424d1e55202dd, content=<a href='/topic/show?id=536f2338e8d' target=_blank style='color:#2F92EE;'>#乙二醇#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23387, encryptionId=536f2338e8d, topicName=乙二醇)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b11f36846752, createdName=weiz, createdTime=Mon Nov 26 07:22:00 CST 2018, time=2018-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2055407, encodeId=321f205540e4c, content=<a href='/topic/show?id=002580e74dd' target=_blank style='color:#2F92EE;'>#聚乙二醇化干扰素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80774, encryptionId=002580e74dd, topicName=聚乙二醇化干扰素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Sat May 04 09:22:00 CST 2019, time=2019-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793390, encodeId=19571e93390f4, content=<a href='/topic/show?id=318915509d6' target=_blank style='color:#2F92EE;'>#ritonavir#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15509, encryptionId=318915509d6, topicName=ritonavir)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Fri Oct 26 07:22:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426358, encodeId=a972142635809, content=<a href='/topic/show?id=032b948ec5' target=_blank style='color:#2F92EE;'>#IgE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9487, encryptionId=032b948ec5, topicName=IgE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cff4064659, createdName=zhenjiu124, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624581, encodeId=e48c162458121, content=<a href='/topic/show?id=3f2d2e7087' target=_blank style='color:#2F92EE;'>#ARNI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2770, encryptionId=3f2d2e7087, topicName=ARNI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f41c20676233, createdName=gongliu, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337167, encodeId=807433e16735, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue Aug 07 22:40:11 CST 2018, time=2018-08-07, status=1, ipAttribution=)]
    2018-08-09 zhenjiu124

    #IgE#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1702944, encodeId=67f91e0294445, content=<a href='/topic/show?id=72351e25437' target=_blank style='color:#2F92EE;'>#TED#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17254, encryptionId=72351e25437, topicName=TED)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76e230462388, createdName=aliceclz, createdTime=Sun Aug 12 18:22:00 CST 2018, time=2018-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2021635, encodeId=939b202163574, content=<a href='/topic/show?id=31e8e9669d' target=_blank style='color:#2F92EE;'>#GER#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7966, encryptionId=31e8e9669d, topicName=GER)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Sun Apr 28 18:22:00 CST 2019, time=2019-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1780439, encodeId=de511e80439a1, content=<a href='/topic/show?id=4ccb36214c' target=_blank style='color:#2F92EE;'>#boost#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3621, encryptionId=4ccb36214c, topicName=boost)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Aug 25 15:22:00 CST 2018, time=2018-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1755202, encodeId=424d1e55202dd, content=<a href='/topic/show?id=536f2338e8d' target=_blank style='color:#2F92EE;'>#乙二醇#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23387, encryptionId=536f2338e8d, topicName=乙二醇)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b11f36846752, createdName=weiz, createdTime=Mon Nov 26 07:22:00 CST 2018, time=2018-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2055407, encodeId=321f205540e4c, content=<a href='/topic/show?id=002580e74dd' target=_blank style='color:#2F92EE;'>#聚乙二醇化干扰素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80774, encryptionId=002580e74dd, topicName=聚乙二醇化干扰素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Sat May 04 09:22:00 CST 2019, time=2019-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793390, encodeId=19571e93390f4, content=<a href='/topic/show?id=318915509d6' target=_blank style='color:#2F92EE;'>#ritonavir#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15509, encryptionId=318915509d6, topicName=ritonavir)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Fri Oct 26 07:22:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426358, encodeId=a972142635809, content=<a href='/topic/show?id=032b948ec5' target=_blank style='color:#2F92EE;'>#IgE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9487, encryptionId=032b948ec5, topicName=IgE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cff4064659, createdName=zhenjiu124, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624581, encodeId=e48c162458121, content=<a href='/topic/show?id=3f2d2e7087' target=_blank style='color:#2F92EE;'>#ARNI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2770, encryptionId=3f2d2e7087, topicName=ARNI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f41c20676233, createdName=gongliu, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337167, encodeId=807433e16735, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue Aug 07 22:40:11 CST 2018, time=2018-08-07, status=1, ipAttribution=)]
    2018-08-09 gongliu

    #ARNI#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1702944, encodeId=67f91e0294445, content=<a href='/topic/show?id=72351e25437' target=_blank style='color:#2F92EE;'>#TED#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17254, encryptionId=72351e25437, topicName=TED)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76e230462388, createdName=aliceclz, createdTime=Sun Aug 12 18:22:00 CST 2018, time=2018-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2021635, encodeId=939b202163574, content=<a href='/topic/show?id=31e8e9669d' target=_blank style='color:#2F92EE;'>#GER#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7966, encryptionId=31e8e9669d, topicName=GER)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=48732500158, createdName=12498c32m68暂无昵称, createdTime=Sun Apr 28 18:22:00 CST 2019, time=2019-04-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1780439, encodeId=de511e80439a1, content=<a href='/topic/show?id=4ccb36214c' target=_blank style='color:#2F92EE;'>#boost#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3621, encryptionId=4ccb36214c, topicName=boost)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Sat Aug 25 15:22:00 CST 2018, time=2018-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1755202, encodeId=424d1e55202dd, content=<a href='/topic/show?id=536f2338e8d' target=_blank style='color:#2F92EE;'>#乙二醇#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23387, encryptionId=536f2338e8d, topicName=乙二醇)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b11f36846752, createdName=weiz, createdTime=Mon Nov 26 07:22:00 CST 2018, time=2018-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2055407, encodeId=321f205540e4c, content=<a href='/topic/show?id=002580e74dd' target=_blank style='color:#2F92EE;'>#聚乙二醇化干扰素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80774, encryptionId=002580e74dd, topicName=聚乙二醇化干扰素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f0715, createdName=showtest, createdTime=Sat May 04 09:22:00 CST 2019, time=2019-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1793390, encodeId=19571e93390f4, content=<a href='/topic/show?id=318915509d6' target=_blank style='color:#2F92EE;'>#ritonavir#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15509, encryptionId=318915509d6, topicName=ritonavir)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/3239AC2A9C7E6019A0BC3C0489A21F7A/100, createdBy=c6a52500178, createdName=41514487@qq.com, createdTime=Fri Oct 26 07:22:00 CST 2018, time=2018-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1426358, encodeId=a972142635809, content=<a href='/topic/show?id=032b948ec5' target=_blank style='color:#2F92EE;'>#IgE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9487, encryptionId=032b948ec5, topicName=IgE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cff4064659, createdName=zhenjiu124, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624581, encodeId=e48c162458121, content=<a href='/topic/show?id=3f2d2e7087' target=_blank style='color:#2F92EE;'>#ARNI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2770, encryptionId=3f2d2e7087, topicName=ARNI)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f41c20676233, createdName=gongliu, createdTime=Thu Aug 09 12:22:00 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337167, encodeId=807433e16735, content=不错的文章值得拥有哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue Aug 07 22:40:11 CST 2018, time=2018-08-07, status=1, ipAttribution=)]
    2018-08-07 1e1b8538m79(暂无匿称)

    不错的文章值得拥有哦

    0

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