2005年SCIENCE公布125个科学前沿问题，如今解决了多少？

2014-03-30 佚名科学网

在庆祝SCIENCE创刊125周年之际，该刊杂志社公布了125个最具挑战性的科学问题，发表在7月1日出版的专辑上。在今后1／4个世纪的时间里，人们将致力于研究解决这些问题。这125个问题如下(前25个被认为是最重要的问题)：1宇宙由什么构成?2意识的生物学基础是什么?3为什么人类基因会如此之少?4遗传变异与人类健康的相关程度如何?5物理定律能否统一?6人类寿命到底可以延长多久?7是什么控制着器

这么多年过去了，2005年SCIENCE公布125个科学前沿问题，如今解决了多少？在今后的时间里，人们又将继续致力于哪些研究？这125个问题如下(前25个被认为是最重要的问题)：

1宇宙由什么构成?

2意识的生物学基础是什么?

3为什么人类基因会如此之少?

4遗传变异与人类健康的相关程度如何?

5物理定律能否统一?

6人类寿命到底可以延长多久?

7是什么控制着器官再生?

8皮肤细胞如何成为神经细胞?

9单个体细胞怎样成为整株植物?

10地球内部如何运行?

11地球人类在宇宙中是否独一无二?

12地球生命在何处产生、如何产生?

13什么决定了物种的多样性?

14什么基因的改变造就了独特的人类?

15记忆如何存储和恢复?

16人类合作行为如何发展?

17怎样从海量生物数据中产生大的可视图片?

18化学自组织的发展程度如何?

19什么是传统计算的极限?

20我们能否有选择地切断某些免疫反应?

21量子不确定性和非局部性背后是否有更深刻的原理?

22能否研制出有效的HIV疫苗?

23温室效应会使地球温度达到多高?

24什么时间用什么能源可以替代石油?

25地球到底能负担多少人口?

26宇宙是否唯一?

27是什么驱动宇宙膨胀?

28第一颗恒星与星系何时产生、怎样产生?

29超高能宇宙射线来自何处?

30是什么给类星体提供动力?

31黑洞的本质是什么?

32正物质为何多于反物质?

33质子会衰减吗?

34重力的本质是什么?

35时间为何不同于其他维度?

36是否存在比夸克更小的基本粒子?

37中微子是其自己的反粒子吗?

38是否有解释所有相关电子系统的统一理论?

39人类能够制造最强的激光吗?

40能否制造完美的光学透镜?

41是否可能制造出室温下的磁性半导体?

42什么是高温超导性之后的成对机制?

43能否发展关于湍流动力学和颗粒材料运动学的综合理论?

44是否存在稳定的高原子量元素?

45固体中是否有超流动性?如果有，如何解释?

46水的结构如何?

47玻璃态物质的本质是什么?

48是否存在合理化学合成的极限?

49光电电池的最终效率如何?

50核聚变将最终成为未来的能源吗?

51驱动太阳磁周期的原因是什么?

52行星怎样形成?

53是什么引发了冰期?

54使地球磁场逆转的原因是什么?

55是否存在有助于预报的地震先兆?

56太阳系的其他星球上现在和过去是否存在生命?

57自然界中手性原则的起源是什么?

58能否预测蛋白质折叠?

59人体中的蛋白质有多少存在方式?

60蛋白质如何发现其作用对象?

61细胞死亡有多少种形式?

62是什么保持了细胞内的通行顺畅?

63为什么细胞的成分可以独立于DNA而自行复制?

64基因组中功能不同于RNA的角色是什么?

65基因组中端粒和丝粒的作用是什么?

66为什么一些基因组很大，另一些又相当紧凑?

67基因组中的“垃圾”(“junk”)有何作用?

68新技术能使DNA测序的成本降低多少?

69器官和整个有机体如何了解停止生长的时间?

70除了继承突变，基因组如何改变?

71在胚胎期，不对称现象是如何确定的?

72翼、鳍和面孔如何发育进化?

73是什么引发了青春期?

74干细胞是否位于所有肿瘤的中心?

75肿瘤更容易通过免疫进行控制吗?

76肿瘤的控制比治愈是否更容易?

77炎症是所有慢性疾病的主要原因吗?

78疯牛病会怎样发展?

79脊椎动物在多大程度上依赖先天免疫系统来抵抗传染病?

80对抗原而言，免疫记忆需要延长暴露吗?

81为什么孕妇的免疫系统不拒绝其胎儿?

82什么与有机体的生物钟同步?

83迁徙生物怎样发现其迁移路线?

84为什么要睡眠?

85人类为什么会做梦?

86语言学习为什么存在临界期?

87信息素影响人类行为吗?

88一般麻醉剂如何发挥作用?

89导致精神分裂症的原因是什么?

90引发孤独症的原因是什么?

91阿兹海默症患者的生命能够延续多久?

92致瘾的生物学基础是什么?

93大脑如何建立道德观念?

94通过计算机进行学习的极限是什么?

95有多少个性源于遗传?

96性别倾向的生物学根源是什么?

97生命树是生命之间系统关系最好的表达方式吗?

98地球上有多少物种? 99什么是物种?

100横向转移为什么会发生在众多的物种中以及如何发生?

101谁是世界的共同祖先?

102植物的花朵如何进化?

103植物怎样制造细胞壁?

104如何控制植物生长?

105为什么所有的植物不能免疫一切疾病?

106外界压力环境下，植物的变异基础是什么?

107是什么引起物质消失?

108能否避免物种消亡?

109一些恐龙为什么如此庞大?

110生态系统对全球变暖的反应如何?

111至今共有多少人种，他们之间有何关联?

112是什么提升了现代人类的行为?

113什么是人类文化的根源?

114语言和音乐演化的根源是什么?

115什么是人种，人种如何进化?

116为什么一些国家向前发展，而有些国家的发展停滞?

117政府高额赤字对国家利益和经济增长速度有什么影响?

118政治与经济自由密切相关吗?

119为什么改变撒哈拉地区贫困状态的努力几乎全部失败?

120有没有简单的方法确定椭圆曲线是否存在无穷多解?

121霍奇闭链是代数闭链的和吗?

122数学家将会最终给出Navier-Stokes方程的解吗?

123庞加莱实验能否确定4维空间的球?

124黎曼zeta函数的零解都有a+bi形式吗?

125对粒子物理标准模型的研究是否会停止在量子Yahg-Mills理论上?

(注：最后6个数学问题选自Clay数学研究所提出的新千年问题)

简单归纳统计这125个问题，其中涉及生命科学的问题占46%，关系宇宙和地球的问题占16%，与物质科学相关的问题占14%以上，认知科学问题占9%。其余问题分别涉及数学与计算机科学、政治与经济、能源、环境和人口等。

原始出处

So Much More to Know … Science 1 July 2005:

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2014-04-02 27.16.39.102

还有什么重要或更重要的“科学”问题?

141 0
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2014-04-01 172.56.8.126

God 是人类共同祖先

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2014-04-01 jichang

#SCIE#

56 0
[GetPortalCommentsPageByObjectIdResponse(id=8807, encodeId=3e1a880e08, content=还有什么重要或更重要的“科学”问题?, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=27.16.39.102, createdTime=Wed Apr 02 19:30:00 CST 2014, time=2014-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8797, encodeId=ebab8e979d, content=God 是人类共同祖先, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=172.56.8.126, createdTime=Tue Apr 01 11:35:00 CST 2014, time=2014-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374858, encodeId=b92b13e485862, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Tue Apr 01 11:17:00 CST 2014, time=2014-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8785, encodeId=70c08e8542, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8786, encodeId=57498e86f1, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8787, encodeId=d3078e8780, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8783, encodeId=df308e83b3, content=好复杂啊，不管了，管俺今年挣多少钱吧！, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=115.231.71.204, createdTime=Sun Mar 30 21:57:00 CST 2014, time=2014-03-30, status=1, ipAttribution=)]
2014-03-31 114.253.210.167

念头很重要，善念更重要！管好他。

135 0
[GetPortalCommentsPageByObjectIdResponse(id=8807, encodeId=3e1a880e08, content=还有什么重要或更重要的“科学”问题?, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=27.16.39.102, createdTime=Wed Apr 02 19:30:00 CST 2014, time=2014-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8797, encodeId=ebab8e979d, content=God 是人类共同祖先, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=172.56.8.126, createdTime=Tue Apr 01 11:35:00 CST 2014, time=2014-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374858, encodeId=b92b13e485862, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Tue Apr 01 11:17:00 CST 2014, time=2014-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8785, encodeId=70c08e8542, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8786, encodeId=57498e86f1, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8787, encodeId=d3078e8780, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8783, encodeId=df308e83b3, content=好复杂啊，不管了，管俺今年挣多少钱吧！, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=115.231.71.204, createdTime=Sun Mar 30 21:57:00 CST 2014, time=2014-03-30, status=1, ipAttribution=)]
2014-03-31 114.253.210.167

念头很重要，善念更重要！管好他。

139 0
[GetPortalCommentsPageByObjectIdResponse(id=8807, encodeId=3e1a880e08, content=还有什么重要或更重要的“科学”问题?, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=27.16.39.102, createdTime=Wed Apr 02 19:30:00 CST 2014, time=2014-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8797, encodeId=ebab8e979d, content=God 是人类共同祖先, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=172.56.8.126, createdTime=Tue Apr 01 11:35:00 CST 2014, time=2014-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374858, encodeId=b92b13e485862, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Tue Apr 01 11:17:00 CST 2014, time=2014-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8785, encodeId=70c08e8542, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8786, encodeId=57498e86f1, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8787, encodeId=d3078e8780, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8783, encodeId=df308e83b3, content=好复杂啊，不管了，管俺今年挣多少钱吧！, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=115.231.71.204, createdTime=Sun Mar 30 21:57:00 CST 2014, time=2014-03-30, status=1, ipAttribution=)]
2014-03-31 114.253.210.167

念头很重要，善念更重要！管好他。

136 0
[GetPortalCommentsPageByObjectIdResponse(id=8807, encodeId=3e1a880e08, content=还有什么重要或更重要的“科学”问题?, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=27.16.39.102, createdTime=Wed Apr 02 19:30:00 CST 2014, time=2014-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8797, encodeId=ebab8e979d, content=God 是人类共同祖先, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=172.56.8.126, createdTime=Tue Apr 01 11:35:00 CST 2014, time=2014-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1374858, encodeId=b92b13e485862, content=<a href='/topic/show?id=2949159989d' target=_blank style='color:#2F92EE;'>#SCIE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15998, encryptionId=2949159989d, topicName=SCIE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=17a3387, createdName=jichang, createdTime=Tue Apr 01 11:17:00 CST 2014, time=2014-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8785, encodeId=70c08e8542, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8786, encodeId=57498e86f1, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8787, encodeId=d3078e8780, content=念头很重要，善念更重要！管好他。, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=114.253.210.167, createdTime=Mon Mar 31 15:33:00 CST 2014, time=2014-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8783, encodeId=df308e83b3, content=好复杂啊，不管了，管俺今年挣多少钱吧！, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=115.231.71.204, createdTime=Sun Mar 30 21:57:00 CST 2014, time=2014-03-30, status=1, ipAttribution=)]
2014-03-30 115.231.71.204

好复杂啊，不管了，管俺今年挣多少钱吧！

81 0

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