Baidu
map

药械

订阅

MedSci主页 / 所有栏目 / 药械

假如“神药”二甲双胍有朋友圈

2016-12-11 佚名 生物谷

二甲双胍朋友圈
关注

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1670911, encodeId=3eff16e09112d, content=<a href='/topic/show?id=92bf60e12b4' target=_blank style='color:#2F92EE;'>#朋友圈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60712, encryptionId=92bf60e12b4, topicName=朋友圈)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ca6426781117, createdName=axin018, createdTime=Mon Feb 20 23:22:00 CST 2017, time=2017-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162207, encodeId=989d16220ecd, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Dec 12 16:05:01 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162027, encodeId=884e16202ee7, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Sun Dec 11 22:56:27 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162024, encodeId=544516202470, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f261920920, createdName=上邪zyy, createdTime=Sun Dec 11 22:45:20 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162023, encodeId=6255162023f6, content=哈哈哈，好搞笑啊！笑疯了！我一边看一边忍不住念出声来！真的很逗啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161012/IMG57FE1FD78F2DB8136.jpg, createdBy=54091964833, createdName=小鑫啊小心, createdTime=Sun Dec 11 22:39:51 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2017-02-20 axin018

    #朋友圈#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1670911, encodeId=3eff16e09112d, content=<a href='/topic/show?id=92bf60e12b4' target=_blank style='color:#2F92EE;'>#朋友圈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60712, encryptionId=92bf60e12b4, topicName=朋友圈)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ca6426781117, createdName=axin018, createdTime=Mon Feb 20 23:22:00 CST 2017, time=2017-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162207, encodeId=989d16220ecd, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Dec 12 16:05:01 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162027, encodeId=884e16202ee7, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Sun Dec 11 22:56:27 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162024, encodeId=544516202470, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f261920920, createdName=上邪zyy, createdTime=Sun Dec 11 22:45:20 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162023, encodeId=6255162023f6, content=哈哈哈，好搞笑啊！笑疯了！我一边看一边忍不住念出声来！真的很逗啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161012/IMG57FE1FD78F2DB8136.jpg, createdBy=54091964833, createdName=小鑫啊小心, createdTime=Sun Dec 11 22:39:51 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-12 现在

    学习中…………

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1670911, encodeId=3eff16e09112d, content=<a href='/topic/show?id=92bf60e12b4' target=_blank style='color:#2F92EE;'>#朋友圈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60712, encryptionId=92bf60e12b4, topicName=朋友圈)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ca6426781117, createdName=axin018, createdTime=Mon Feb 20 23:22:00 CST 2017, time=2017-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162207, encodeId=989d16220ecd, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Dec 12 16:05:01 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162027, encodeId=884e16202ee7, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Sun Dec 11 22:56:27 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162024, encodeId=544516202470, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f261920920, createdName=上邪zyy, createdTime=Sun Dec 11 22:45:20 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162023, encodeId=6255162023f6, content=哈哈哈，好搞笑啊！笑疯了！我一边看一边忍不住念出声来！真的很逗啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161012/IMG57FE1FD78F2DB8136.jpg, createdBy=54091964833, createdName=小鑫啊小心, createdTime=Sun Dec 11 22:39:51 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-11 现在

    学习中…………

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1670911, encodeId=3eff16e09112d, content=<a href='/topic/show?id=92bf60e12b4' target=_blank style='color:#2F92EE;'>#朋友圈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60712, encryptionId=92bf60e12b4, topicName=朋友圈)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ca6426781117, createdName=axin018, createdTime=Mon Feb 20 23:22:00 CST 2017, time=2017-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162207, encodeId=989d16220ecd, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Dec 12 16:05:01 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162027, encodeId=884e16202ee7, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Sun Dec 11 22:56:27 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162024, encodeId=544516202470, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f261920920, createdName=上邪zyy, createdTime=Sun Dec 11 22:45:20 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162023, encodeId=6255162023f6, content=哈哈哈，好搞笑啊！笑疯了！我一边看一边忍不住念出声来！真的很逗啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161012/IMG57FE1FD78F2DB8136.jpg, createdBy=54091964833, createdName=小鑫啊小心, createdTime=Sun Dec 11 22:39:51 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-11 上邪zyy

    有意思

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1670911, encodeId=3eff16e09112d, content=<a href='/topic/show?id=92bf60e12b4' target=_blank style='color:#2F92EE;'>#朋友圈#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60712, encryptionId=92bf60e12b4, topicName=朋友圈)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ca6426781117, createdName=axin018, createdTime=Mon Feb 20 23:22:00 CST 2017, time=2017-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162207, encodeId=989d16220ecd, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Mon Dec 12 16:05:01 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162027, encodeId=884e16202ee7, content=学习中…………, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161126/IMG5838DBFDE7ED75013.jpg, createdBy=01ac1975851, createdName=现在, createdTime=Sun Dec 11 22:56:27 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162024, encodeId=544516202470, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0f261920920, createdName=上邪zyy, createdTime=Sun Dec 11 22:45:20 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162023, encodeId=6255162023f6, content=哈哈哈，好搞笑啊！笑疯了！我一边看一边忍不住念出声来！真的很逗啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161012/IMG57FE1FD78F2DB8136.jpg, createdBy=54091964833, createdName=小鑫啊小心, createdTime=Sun Dec 11 22:39:51 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-11 小鑫啊小心

    哈哈哈，好搞笑啊！笑疯了！我一边看一边忍不住念出声来！真的很逗啊

    0

相关资讯

CDS 2016：李光伟教授谈糖尿病预防，生活方式干预还是药物干预

糖尿病的洪流无情地冲刷着伟大祖国的每一寸土地。从大东北到大西南的每个城市和农村无一能幸免，我们每乘坐一次飞机、一次汽车、甚至每乘坐一次电梯都可能有糖尿病人相伴……无数指南推动的“每天服用20片药”，“三年放五枚支架”的治疗没能阻挡糖尿病害人的脚步，反而掏空了人们的腰包。活到70岁以上者：DM中占56%，NGT中占78%，糖尿病人群任何死亡比血糖正常者要提前10年。中国大庆地区筛查糖尿病人群心血管死

二甲双胍这20问，共识怎么说？

65岁以上老年患者如何使用二甲双胍？肾功能不全的T2DM 患者使用二甲双胍应注意哪些问题？二甲双胍是否具有抗肿瘤作用？......这些有关二甲双胍的常见问题，看最新的《二甲双胍临床应用专家共识（2016版）》如何说明！近日，国内内分泌临床专家、药学专家对2014年版《二甲双胍临床应用专家共识》进行了更新，制定了《二甲双胍临床应用专家共识（2016版）》。小编这边介绍关于二甲双胍在特殊人群中的使

Diabetes Care：二甲双胍是如何改变肠道菌群的？

最近的研究表明，二甲双胍对糖代谢的作用可能是微生物介导的。我们研究了2型糖尿病/二甲双胍和肠道菌群之间的关联。在前人研究的基础上，我们推测，二甲双胍与能产生高水平的短链脂肪酸(SCFA)和粘蛋白降解的菌群有关。 研究纳入459例患者，目前的分析集中在28名确诊为糖尿病的患者中，其中14例服用二甲双胍，还有84例患者没有糖尿病，在性别、年龄和BMI上与糖尿病患者匹配。 我们测量了人口信息

J Diabetes：西他列汀+二甲双胍 vs 磺酰脲类+二甲双胍，依从性更好

研究数据显示,服用西他列汀+二甲双胍的成年患者与服用磺酰脲类+二甲双胍的成年人相比，依从性和持久性均更好。 来自默克观测和真实世界证据研究中心的Swapnil N. Rajpathak博士和同事对14807名服用磺酰脲类+二甲双胍、14807名服用西他列汀+二甲双胍的2型糖尿病患只进行了研究。 服用西他列汀+二甲双胍的成年患者与服用磺酰脲类+二甲双胍的成年人相比，有更高的1年平均药物覆

DPP-4抑制剂多重获益，助力中国2型糖尿病管理

直击2型糖尿病发病核心因素，DPP-4抑制剂西格列汀保护胰岛功能延缓疾病进展从作用机制上看，西格列汀通过抑制DPP-4增加活性胰高糖素样肽1（GLP-1）水平，呈葡萄糖依赖性降低血糖。研究显示，糖尿病患者的β细胞比例（0.45）较非糖尿病患者降低（0.82）、α细胞比例升高（0.36对0.07），应用西格列汀可使β细胞/总胰岛面积、α细胞/总胰岛面积恢复至接近正常水平（分别为0.71和0.22

抗炎、抗癌、抗感染，为何二甲双胍如此多用？

上皮组织对于机体各种器官的正常运转不可或缺，其可作为有效的屏障，阻止毒素、病原体、炎症因子等对器官的负面影响。上皮组织的完整性体现在上皮细胞之间的紧密连接以及决定“内外有别”的上皮细胞极性等方面，一旦遭到破坏，可导致器官发育和功能异常，甚至癌变。胁迫等不利条件会威胁到上皮组织的完整性。为此，机体演化出了的胁迫-极性信号通路（stress-polarity pathway）等机制。这一通路由AMPK

Baidu
map
Baidu
map
Baidu
map