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Prostate Cancer P D:双参数MRI和多重参数MRI在检测临床显著前列腺癌中的比较

2018-11-17 AlexYang MedSci原创

多重参数核磁共振成像(MP-MRI)和MRI/超声(US)融合活检在前列腺癌(PCa)诊断和治疗中应用的越来越广泛。然而,这些技术的广泛接受和使用却受到了治疗成本和时间的限制。这些限制可以通过简化流程来最小化其影响,比如聚焦于T2加权和弥散加权的双参数MRI(BP-MRI)。最近,有研究人员就比较了BP-MRI与全MP-MRI在检测癌症中的情况。研究包括了648个靶向病变样本,来自314名患者的活

多重参数核磁共振成像(MP-MRI)和MRI/超声(US)融合活检在前列腺癌(PCa)诊断和治疗中应用的越来越广泛。然而,这些技术的广泛接受和使用却受到了治疗成本和时间的限制。这些限制可以通过简化流程来最小化其影响,比如聚焦于T2加权和弥散加权的双参数MRI(BP-MRI)。最近,有研究人员就比较了BP-MRI与全MP-MRI在检测癌症中的情况。

研究包括了648个靶向病变样本,来自314名患者的活检。研究人员将双参数过滤成像阳性定义为T2加权成像和弥散加权成像在同样的病变部位呈现阳性。研究发现,大多数的靶向病变过滤后均为阳性(552/648,85%)。那些过滤后为阴性的样本,小部分(14/96,15%)具有DCE阳性发现。在这些样本中,2/3(67%)的癌症阳性案例可通过T2加权成像发现。对于那些在过滤阴性和DCE阴性的82个案例中,DCE相位不会增加病理成像的可能。只有3/82(3.7%)为癌症阳性,2名低风险,1名为管内癌,所有3名均在靶向T2加权MRI中为阳性。

最后,研究人员指出,利用BM-MRI对PCa进行评估以及对MRI/US融合靶向活检指导中具有花费少、时间消耗小以及消除DCE相位的MP-MRI对比曝光优势。这些益处的实现不会丧失有价值的诊断信息,并且与MP-MRI具有相似的诊断率,尤其是在临床显著PCa中。

原始出处:

Rachael L. Sherrer, Zachary A. Glaser, Jennifer B. Gordetsky et al. Comparison of biparametric MRI to full multiparametric MRI for detection of clinically significant prostate cancer. Prostate Cancer P D. 09 Nov 2018.

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    2018-11-19 lsndxfj
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    2018-11-19 sunylz
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    2018-11-18 smartxiuxiu

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    2018-11-17 一个字-牛

    学习了谢谢分享

    0

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    2018-11-17 1dd8a7c5m95(暂无匿称)

    好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。

    0

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