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加拿大学者发现服用抗抑郁药可能加倍增加患痴呆症的风险

2017-02-24 佚名 科技部

加拿大萨斯喀彻温大学的研究人员采用医学文献研究方法,发现位列全球处方药前列的抗抑郁药,有可能助长阿尔茨海默症和其他脑损伤痴呆症的发生。研究团队利用医学文献研究方法,对4123篇医学文章进行筛选,最后选择出5篇符合他们研究标准的文章,这5篇文章共涉及约150万人。



加拿大萨斯喀彻温大学的研究人员采用医学文献研究方法,发现位列全球处方药前列的抗抑郁药,有可能助长阿尔茨海默症和其他脑损伤痴呆症的发生。研究团队利用医学文献研究方法,对4123篇医学文章进行筛选,最后选择出5篇符合他们研究标准的文章,这5篇文章共涉及约150万人。

研究发现,服用比较受欢迎的被称为选择性5-羟色胺再摄取抑制剂(SSRIs)的一种治疗精神抑郁的药以及其它抗抑郁药,与包括阿尔茨海默症在内的一些痴呆症发病率加倍增长密切相关。年龄对服用抗抑郁药和患认知损害疾病或阿尔茨海默症/痴呆症之间有相关影响,平均年龄在65岁以上服用抗抑郁药的人患认知损害疾病的几率会增加。相关研究成果发表在2016年12月28日的《抑郁和焦虑》(Depression and Anxiety)杂志上。

该研究虽然没有证明原因和结果,但是,他们的发现会激发起人们对一系列抗抑郁药物的关注。这些药物被广泛和不加选择地用于治疗从普通的“悲伤”到失眠、疼痛和热潮红等各种疾病。抗抑郁药虽然对一些人确实有用,但研究人员确实发现抗抑郁药与痴呆之间有相关性。科学家一直在寻找导致痴呆症的因素,抑郁症可能是其中一个因素,但不是每一个有抑郁的人会得阿尔茨海默病,也不是每一个患阿尔茨海默病的人会都有抑郁症。

加拿大位列世界抗抑郁药使用前列,根据IMS Brogan公司的市场研究,加拿大2015年开出超过5千万份抗抑郁药处方。同时,由于人的寿命增长,得阿尔茨海默症和其他脑疾病的人在增加。目前全球约有4750万人患痴呆症,加拿大有75万人,预计在未来15年会增加一倍。

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    2017-06-30 Boyinsh
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    2017-06-27 wetgdt
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    2017-02-28 QQ713279ab

    新视角,有探索有收获

    0

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