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Sci Rep:小儿单独遗尿症状的警报治疗与去氨加压素治疗系统回顾与元分析

2018-11-26 AlexYang MedSci原创

最近,有研究人员比较了警报治疗与去氨加压素治疗在控制儿科单独遗尿症上的效果。研究人员在不同的数据库中系统的搜索了相关文献,时间为从开始到2017年4月,并且不受语言限制。研究包括了所有那些随机对照试验,这些试验比较了警报治疗与去氨加压素治疗在控制儿科单独遗尿症方面的效果。研究总共包括了15个报道的研究,总共有1502名参与者(年龄在5到16岁)。总体来讲,在按照方案分析中,警报治疗要比去氨加压素治

最近,有研究人员比较了警报治疗与去氨加压素治疗在控制儿科单独遗尿症上的效果。研究人员在不同的数据库中系统的搜索了相关文献,时间为从开始到2017年4月,并且不受语言限制。

研究包括了所有那些随机对照试验,这些试验比较了警报治疗与去氨加压素治疗在控制儿科单独遗尿症方面的效果。研究总共包括了15个报道的研究,总共有1502名参与者(年龄在5到16岁)。总体来讲,在按照方案分析中,警报治疗要比去氨加压素治疗效果更好,至少在部分方面响应是更好的(遗尿有50%的减少)(OR: 1.53, 95% CI 1.05 to 2.23),但是在意向处理分析中并非如此(OR: 0.97, 95% CI 0.73 to 1.30),警报治疗由于高度的放弃比例而受到阻碍(OR: 2.20, 95% CI 3.41 to 4.29)。然而,警报治疗能够产出更好的持久的响应(OR: 2.89, 95% CI 1.38 to 6.04)和更低的复发比例(OR: 0.25, 95% CI 0.12 to 0.50)。在意向处理分析中,结果表明了警报与去氨加压素治疗在减少夜尿方面是不相上下的,均能够在遗尿儿童中达到减少50%比例的效果。

最后,研究人员指出,警报治疗能够获得更好的治疗效果,并且复发率更低。

原始出处:

Carol Chiung-Hui Peng, Stephen Shei-Dei Yang, Paul F. Austin et al. Systematic Review and Meta-analysis of Alarm versus Desmopressin Therapy for Pediatric Monosymptomatic Enuresis. Sci Rep. 13 Nov 2018.

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    2019-08-25 fyxzlh
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1905841, encodeId=675419058419b, content=<a href='/topic/show?id=8f2f28546b3' target=_blank style='color:#2F92EE;'>#元分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28546, encryptionId=8f2f28546b3, topicName=元分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=jiangjun073, createdTime=Sun Jun 16 18:35:00 CST 2019, time=2019-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945405, encodeId=ed84194540502, content=<a href='/topic/show?id=91f39522997' target=_blank style='color:#2F92EE;'>#遗尿症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95229, encryptionId=91f39522997, topicName=遗尿症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3eaf430, createdName=bsmagic9132, createdTime=Sun May 05 08:35:00 CST 2019, time=2019-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1992050, encodeId=456b199205043, content=<a href='/topic/show?id=11b13296e8e' target=_blank style='color:#2F92EE;'>#加压素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32967, encryptionId=11b13296e8e, topicName=加压素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Sun Aug 25 12:35:00 CST 2019, time=2019-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009501, encodeId=22f920095018f, content=<a href='/topic/show?id=1e203e249c3' target=_blank style='color:#2F92EE;'>#去氨加压素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37249, encryptionId=1e203e249c3, topicName=去氨加压素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9b30126, createdName=skhzy, createdTime=Sat Sep 28 19:35:00 CST 2019, time=2019-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1721650, encodeId=3aca1e21650a5, content=<a href='/topic/show?id=4384911095b' target=_blank style='color:#2F92EE;'>#警报治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91109, encryptionId=4384911095b, topicName=警报治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=078e33056309, createdName=wangtianj2018@, createdTime=Mon Sep 09 13:35:00 CST 2019, time=2019-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576400, encodeId=a58715e64009a, content=<a href='/topic/show?id=e02ee6901a2' target=_blank style='color:#2F92EE;'>#系统回顾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76901, encryptionId=e02ee6901a2, topicName=系统回顾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27e316318097, createdName=ms5822920152752585, createdTime=Wed Nov 28 03:35:00 CST 2018, time=2018-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353706, encodeId=65e7353e0624, content=认真学习,不断进步,把经验分享给同好。点赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Mon Nov 26 13:12:07 CST 2018, time=2018-11-26, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1905841, encodeId=675419058419b, content=<a href='/topic/show?id=8f2f28546b3' target=_blank style='color:#2F92EE;'>#元分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28546, encryptionId=8f2f28546b3, topicName=元分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=jiangjun073, createdTime=Sun Jun 16 18:35:00 CST 2019, time=2019-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945405, encodeId=ed84194540502, content=<a href='/topic/show?id=91f39522997' target=_blank style='color:#2F92EE;'>#遗尿症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95229, encryptionId=91f39522997, topicName=遗尿症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3eaf430, createdName=bsmagic9132, createdTime=Sun May 05 08:35:00 CST 2019, time=2019-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1992050, encodeId=456b199205043, content=<a href='/topic/show?id=11b13296e8e' target=_blank style='color:#2F92EE;'>#加压素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32967, encryptionId=11b13296e8e, topicName=加压素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Sun Aug 25 12:35:00 CST 2019, time=2019-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009501, encodeId=22f920095018f, content=<a href='/topic/show?id=1e203e249c3' target=_blank style='color:#2F92EE;'>#去氨加压素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37249, encryptionId=1e203e249c3, topicName=去氨加压素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9b30126, createdName=skhzy, createdTime=Sat Sep 28 19:35:00 CST 2019, time=2019-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1721650, encodeId=3aca1e21650a5, content=<a href='/topic/show?id=4384911095b' target=_blank style='color:#2F92EE;'>#警报治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91109, encryptionId=4384911095b, topicName=警报治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=078e33056309, createdName=wangtianj2018@, createdTime=Mon Sep 09 13:35:00 CST 2019, time=2019-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576400, encodeId=a58715e64009a, content=<a href='/topic/show?id=e02ee6901a2' target=_blank style='color:#2F92EE;'>#系统回顾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76901, encryptionId=e02ee6901a2, topicName=系统回顾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27e316318097, createdName=ms5822920152752585, createdTime=Wed Nov 28 03:35:00 CST 2018, time=2018-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353706, encodeId=65e7353e0624, content=认真学习,不断进步,把经验分享给同好。点赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Mon Nov 26 13:12:07 CST 2018, time=2018-11-26, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1905841, encodeId=675419058419b, content=<a href='/topic/show?id=8f2f28546b3' target=_blank style='color:#2F92EE;'>#元分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28546, encryptionId=8f2f28546b3, topicName=元分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=jiangjun073, createdTime=Sun Jun 16 18:35:00 CST 2019, time=2019-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1945405, encodeId=ed84194540502, content=<a href='/topic/show?id=91f39522997' target=_blank style='color:#2F92EE;'>#遗尿症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95229, encryptionId=91f39522997, topicName=遗尿症)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3eaf430, createdName=bsmagic9132, createdTime=Sun May 05 08:35:00 CST 2019, time=2019-05-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1992050, encodeId=456b199205043, content=<a href='/topic/show?id=11b13296e8e' target=_blank style='color:#2F92EE;'>#加压素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32967, encryptionId=11b13296e8e, topicName=加压素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c9df476, createdName=fyxzlh, createdTime=Sun Aug 25 12:35:00 CST 2019, time=2019-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2009501, encodeId=22f920095018f, content=<a href='/topic/show?id=1e203e249c3' target=_blank style='color:#2F92EE;'>#去氨加压素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37249, encryptionId=1e203e249c3, topicName=去氨加压素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9b30126, createdName=skhzy, createdTime=Sat Sep 28 19:35:00 CST 2019, time=2019-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1721650, encodeId=3aca1e21650a5, content=<a href='/topic/show?id=4384911095b' target=_blank style='color:#2F92EE;'>#警报治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91109, encryptionId=4384911095b, topicName=警报治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=078e33056309, createdName=wangtianj2018@, createdTime=Mon Sep 09 13:35:00 CST 2019, time=2019-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576400, encodeId=a58715e64009a, content=<a href='/topic/show?id=e02ee6901a2' target=_blank style='color:#2F92EE;'>#系统回顾#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76901, encryptionId=e02ee6901a2, topicName=系统回顾)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=27e316318097, createdName=ms5822920152752585, createdTime=Wed Nov 28 03:35:00 CST 2018, time=2018-11-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=353706, encodeId=65e7353e0624, content=认真学习,不断进步,把经验分享给同好。点赞了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Mon Nov 26 13:12:07 CST 2018, time=2018-11-26, status=1, ipAttribution=)]
    2018-11-26 lietome15

    认真学习,不断进步,把经验分享给同好。点赞了!

    0

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