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CHEST:亚洲人群房颤的终身风险、预计数量和不良结局!

2017-10-14 MedSci MedSci原创

目前,关于房颤(AF)临床流行病学的大部分数据来自西方人群,有关亚洲人群的数据十分有限。近期,一项发表在杂志CHEST上的研究调查了亚洲人AF的终身风险和预计数量,并分析了与非AF患者相比,AF患者不良事件的年度风险和时间趋势。此项研究从2000年开始到2011年,共招募了289,559例年龄≥20岁的台湾新发AF患者。计算受试者房颤的发生率、患病率和终生风险。对AF患者的不良事件风险进行分析,并

目前,关于房颤(AF)临床流行病学的大部分数据来自西方人群,有关亚洲人群的数据十分有限。近期,一项发表在杂志CHEST上的研究调查了亚洲人AF的终身风险和预计数量,并分析了与非AF患者相比,AF患者不良事件的年度风险和时间趋势。


此项研究从2000年开始到2011年,共招募了289,559例年龄≥20岁的台湾新发AF患者。计算受试者房颤的发生率、患病率和终生风险。对AF患者的不良事件风险进行分析,并将其与非AF患者进行了比较。

此项研究结果显示:AF的发生率在2011年为1.51 / 1000人年,其中房颤的终身风险在20岁以上的受试者中约为1/7。至2050年,AF患病率估计为4.01%。与无AF相比,AF患者与死亡风险(调整风险比2.61),心力衰竭(3.31),缺血性卒中(3.34),痴呆(1.56) ),心源性猝死(1.83)和心肌梗塞(1.62)增加有关;所有p值<0.01。缺血性卒中、心力衰竭和死亡率的风险在首次诊断AF后的初始阶段(约6个月)较非AF患者显著增高。

此项研究结果表明:亚洲AF患者的负担正在增加,其中AF的终身风险约为1/7。对任何相关并发症的优化管理应成为AF全面管理中的一部分。

原始出处:
Chao TF, Liu CJ, et al. Lifetime Risks, Projected Numbers and Adverse Outcomes in Asian Patients with Atrial Fibrillation: A Report from the Taiwan Nationwide AF Cohort Study. Chest. 2017 Oct 7. pii: S0012-3692(17)32881-7. doi: 10.1016/j.chest.2017.10.001. 

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    2018-03-02 xiangyuzhou971
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    2018-03-15 Smile2680
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    2017-10-15 明崖

    学习了.好文章

    0

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    2017-10-14 1e0f8808m18(暂无匿称)

    房颤危险因素管理.学习了.

    0

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