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Circulation：减少久坐时间可预防心血管代谢性疾病

2015-10-21 小田 译 医学论坛网

久坐时间心血管代谢性疾病
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久坐与不良健康转归有关。既往研究主要是依赖自我报告数据，尚缺乏客观检测到的久坐时间与心脏代谢生物指标相关性的数据，尤其是在西班牙裔和拉丁裔美国人中。美国学者们近期在上述人群中开展了一项基于人群的相关研究，结果表明，久坐时间和心脏代谢生物指标间存在有害的关系，这种相关性独立于体力活动。研究结果强调了减少久坐时间对于预防心血管代谢性疾病的重要性，即使是在那些满足体力活动推荐量的人群中。相关论文近期

久坐与不良健康转归有关。既往研究主要是依赖自我报告数据，尚缺乏客观检测到的久坐时间与心脏代谢生物指标相关性的数据，尤其是在西班牙裔和拉丁裔美国人中。美国学者们近期在上述人群中开展了一项基于人群的相关研究，结果表明，久坐时间和心脏代谢生物指标间存在有害的关系，这种相关性独立于体力活动。研究结果强调了减少久坐时间对于预防心血管代谢性疾病的重要性，即使是在那些满足体力活动推荐量的人群中。相关论文近期在线发表于《循环》(Circulation)杂志。

研究者们通过运动加速器客观检测了“西班牙社区健康研究/拉丁裔研究”中来自美国4个城市12083例18-74岁人群久坐时间和多种心脏代谢生物指标的相关性。久坐时间(<100计数/分钟)被标准化到的佩戴时间16小时/天。平均久坐时间为11.9小时/天。

结果显示，校正中度至剧烈体力活动和混杂变量后，久坐时间延长与高密度脂蛋白胆固醇(HDL-C)减少有关(P=0.04)，还与甘油三酯水平、餐后2小时血糖和餐后血胰岛素水平以及胰岛素抵抗指数增加有关(所有P值均<0.0001)。这些相关性在不同年龄、性别、西班牙裔和拉丁裔背景以及体力活动水平下依然存在普遍的一致性。即使是在那些满足指南推荐体力活动量的个体中，久坐时间也与若干心脏代谢生物指标(舒张压、HDL-C、空腹和餐后2小时血糖、空腹血胰岛素和胰岛素抵抗指数，所有P值均<0.05)存在有害的关系。

原文出处：

Qibin Qi,et al.Objectively-Measured Sedentary Time and CardiometabolicBiomarkers in U.S. Hispanic/Latino Adults: The HispanicCommunity Health Study/Study of Latinos (HCHS/SOL).CIRCULATIONAHA.2015

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    2016-05-11 fengting3

    #心血管代谢#

    0

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    2016-06-02 sodoo

    #代谢性#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1934406, encodeId=57c41934406df, content=<a href='/topic/show?id=333851e5032' target=_blank style='color:#2F92EE;'>#心血管代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51750, encryptionId=333851e5032, topicName=心血管代谢)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2bcd469, createdName=fengting3, createdTime=Wed May 11 17:13:00 CST 2016, time=2016-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989575, encodeId=804f19895e543, content=<a href='/topic/show?id=5e202543023' target=_blank style='color:#2F92EE;'>#代谢性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25430, encryptionId=5e202543023, topicName=代谢性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6cc1239, createdName=sodoo, createdTime=Thu Jun 02 16:13:00 CST 2016, time=2016-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41134, encodeId=7d0a41134d9, content=讲, beContent=null, objectType=article, channel=null, level=null, likeNumber=212, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150904/IMG55E8DB68F05883098.jpg, createdBy=e00a1631985, createdName=fengzhigu, createdTime=Sun Oct 25 17:20:00 CST 2015, time=2015-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309651, encodeId=33e3130965104, content=<a href='/topic/show?id=9d6c51e5284' target=_blank style='color:#2F92EE;'>#心血管代谢性疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51752, encryptionId=9d6c51e5284, topicName=心血管代谢性疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3d1e370, createdName=yibei, createdTime=Fri Oct 23 00:13:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40081, encodeId=da144008145, content=不能久坐！, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Wed Oct 21 19:15:00 CST 2015, time=2015-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40066, encodeId=3cfb4006622, content=这是显而易见的, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Wed Oct 21 13:52:00 CST 2015, time=2015-10-21, status=1, ipAttribution=)]
    2015-10-25 fengzhigu

    讲

    0

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    2015-10-23 yibei

    #心血管代谢性疾病#

    0

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    2015-10-21 medcardio

    不能久坐！

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1934406, encodeId=57c41934406df, content=<a href='/topic/show?id=333851e5032' target=_blank style='color:#2F92EE;'>#心血管代谢#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51750, encryptionId=333851e5032, topicName=心血管代谢)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2bcd469, createdName=fengting3, createdTime=Wed May 11 17:13:00 CST 2016, time=2016-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989575, encodeId=804f19895e543, content=<a href='/topic/show?id=5e202543023' target=_blank style='color:#2F92EE;'>#代谢性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=25430, encryptionId=5e202543023, topicName=代谢性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6cc1239, createdName=sodoo, createdTime=Thu Jun 02 16:13:00 CST 2016, time=2016-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=41134, encodeId=7d0a41134d9, content=讲, beContent=null, objectType=article, channel=null, level=null, likeNumber=212, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150904/IMG55E8DB68F05883098.jpg, createdBy=e00a1631985, createdName=fengzhigu, createdTime=Sun Oct 25 17:20:00 CST 2015, time=2015-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309651, encodeId=33e3130965104, content=<a href='/topic/show?id=9d6c51e5284' target=_blank style='color:#2F92EE;'>#心血管代谢性疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51752, encryptionId=9d6c51e5284, topicName=心血管代谢性疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3d1e370, createdName=yibei, createdTime=Fri Oct 23 00:13:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40081, encodeId=da144008145, content=不能久坐！, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Wed Oct 21 19:15:00 CST 2015, time=2015-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=40066, encodeId=3cfb4006622, content=这是显而易见的, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJXCR8W80NNgQuicJU3aIm3JtiaNAFLYSMlBuVfGkSlw5Z5VpmZK4PyiaDURLAorhvwhWVnaM1gQdJXA/132, createdBy=a01444383, createdName=lixh1719, createdTime=Wed Oct 21 13:52:00 CST 2015, time=2015-10-21, status=1, ipAttribution=)]
    2015-10-21 lixh1719

    这是显而易见的

    0

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