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Pediatrics:母乳喂养减少突发性婴儿死亡综合征风险

2017-10-31 海北 MedSci原创

突发性婴儿死亡综合征(SIDS)是导致产后婴儿死亡的主要原因。已报道的荟萃分析显示,任何母乳喂养都对SIDS具有保护功效,而且纯母乳喂养具有更强的效果。

突发性婴儿死亡综合征(SIDS)是导致产后婴儿死亡的主要原因。已报道的荟萃分析显示,任何母乳喂养都对SIDS具有保护功效,而且纯母乳喂养具有更强的效果。但是至今为止,提供保护效果所需的母乳喂养持续时间还是未知数。

来自弗吉尼亚医护大学的研究人员评估了母乳喂养持续时间和SIDS之间的关系。其收集了来自8个病例对照研究的数据。研究人员也确认了母乳喂养变量,人口因素和其他潜在的混杂因素,并进行了个体研究和汇总分析。

在此次的研究中,研究人员共纳入了2267SIDS病例和6837例参照婴儿。在多变量汇总分析中,<2个月的母乳喂养是不具备保护性的(调整后的比值比[aOR]0.91,95%置信区间[CI]0.68-1.22)。相反,母乳喂养≥2个月是具有保护性的,并且保护作用随着持续时间增加而增加 (2–4个月: aOR: 0.60, 95% CI: 0.44–0.82; 4–6个月0, 95% CI: 0.26–0.63; and >6个月6, 95% CI: 0.22–0.61)

虽然纯母乳喂养<2个月不具备保护作用(aOR0.82, 95CI0.59-1.14),但是更长时间的纯母乳喂养是具有保护性的(2-4个月:aOR0.61, 95CI0.42-0.87; 4-6个月:aOR0.46, 95CI0.29-0.74)。

研究人员也坦言,每个研究中收集的变量略有不同,这限制了其将全部研究纳入所有混杂因素的分析和控制的能力。

因此,研究人员的数据表明,至少2个月的母乳喂养持续时间与SIDS风险的减半相关。要达到这种保护效果,纯母乳喂养不是必须的。


原始出处:

John M.D. Thompson et al. Duration of Breastfeeding and Risk of SIDS: An Individual Participant Data Meta-analysisPediatrics, 2017; e20171324 DOI: 10.1542/peds.2017-1324


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createdBy=987022654425, createdName=ms9608593228839890, createdTime=Tue Jun 26 10:30:00 CST 2018, time=2018-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1803452, encodeId=c1cd18034524b, content=<a href='/topic/show?id=b987e548071' target=_blank style='color:#2F92EE;'>#突发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75480, encryptionId=b987e548071, topicName=突发性)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/L2dMhrxjvSWuPWKZZP1I83Rw21EWia7LVTYJibLQkb4oTibrYLwhnAXntTBWR3FruIzKfNMiaBwhYV0AKNmiaNxfialg/132, createdBy=6ea92500119, createdName=ms9608593228839890, createdTime=Mon Apr 02 14:30:00 CST 2018, time=2018-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1665040, encodeId=b8051665040f9, content=<a href='/topic/show?id=c8664008e1a' target=_blank 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 31 15:04:28 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257525, encodeId=757e25e525a8, content=母乳喂养**的.., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Oct 31 14:35:16 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
  5. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 31 15:04:28 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257525, encodeId=757e25e525a8, content=母乳喂养**的.., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Oct 31 14:35:16 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
    2017-12-30 hbwxf
  6. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 31 15:04:28 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257525, encodeId=757e25e525a8, content=母乳喂养**的.., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Oct 31 14:35:16 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
    2017-11-02 villahu
  7. 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  8. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 31 15:04:28 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257525, encodeId=757e25e525a8, content=母乳喂养**的.., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Oct 31 14:35:16 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
    2017-10-31 Y—xianghai

    学习了新知识

    0

  9. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Tue Oct 31 15:04:28 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257525, encodeId=757e25e525a8, content=母乳喂养**的.., beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Tue Oct 31 14:35:16 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
    2017-10-31 Y—xianghai

    学习了新知识

    0

  10. 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    2017-10-31 1e0f8808m18(暂无匿称)

    母乳喂养**的..

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