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Am J Clin Nutr：配方奶的蛋白含量并不是越高越好

2016-09-13 Mechront 译 MedSci原创

配方奶母乳WHO
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对于不完全母乳喂养的婴儿，在婴儿期摄入高蛋白饮食，可能会增加以后肥胖的风险。降低婴儿配方奶粉中的蛋白质含量，使其更接近成熟母乳，可能会降低配方奶喂养婴儿的超重或肥胖长期风险。 通过与WHO生长标准和母乳喂养婴儿进行比较，我们评估了含1.8 g/100 kcal蛋白（低于目前大多数配方奶，更接近母乳）的乳清蛋白为主的配方奶对婴儿生长发育的影响。 使用来自11项随机对照试验的健康足月婴儿(

对于不完全母乳喂养的婴儿，在婴儿期摄入高蛋白饮食，可能会增加以后肥胖的风险。降低婴儿配方奶粉中的蛋白质含量，使其更接近成熟母乳，可能会降低配方奶喂养婴儿的超重或肥胖长期风险。

通过与WHO生长标准和母乳喂养婴儿进行比较，我们评估了含1.8 g/100 kcal蛋白（低于目前大多数配方奶，更接近母乳）的乳清蛋白为主的配方奶对婴儿生长发育的影响。

使用来自11项随机对照试验的健康足月婴儿(n = 1882)数据进行了多中心合并分析。评估低蛋白婴儿配方奶粉(LPF)或LPF+活性成分（益生菌、益生元或两者均有）(LPFA)和母乳喂养婴儿4个月时，年龄标准体重z分数(WAZ)、年龄相关身高、年龄相关BMI、年龄相关头围z分数

LPF组和LPFA组的WAZ分别为0.07 (−0.16, 0.29)和0.22 (0.01, 0.43)。与母乳喂养婴儿相比，LPF (P < 0.001)和LPFA (P = 0.003)组WAZ更高；与WHO生长标准相比，母乳喂养婴儿更有可能有相对较低的WAZ[−0.23 (−0.51, 0.05)]。LPF组和LPFA组婴儿的其他指标z分数均在WHO生长标准的±0.5 SD内，但是要除外头围，其上限已经稍微超出了0.5 SD。LPF组和LPFA组之间的比较，没有发现任何指标z分数的差异。

结果表明，与WHO生长标准和母乳喂养婴儿比较，乳清蛋白为主的低蛋白质含量、更接近母乳的婴儿配方奶粉，能够支持婴儿的健康成长。

原始出处：

Dominik D Alexander.et al.Growth of infants consuming whey-predominant term infant formulas with a protein content of 1.8 g/100 kcal: a multicenter pooled analysis of individual participant data.Am J Clin Nutr ajcn130633; First published online September 7, 2016

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    2016-12-30 venlin

    #配方奶#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1945416, encodeId=27721945416b4, content=<a href='/topic/show?id=96b89544950' target=_blank style='color:#2F92EE;'>#配方奶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95449, encryptionId=96b89544950, topicName=配方奶)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aae2431, createdName=venlin, createdTime=Fri Dec 30 04:50:00 CST 2016, time=2016-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126234, encodeId=f105126234d8, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Sep 14 09:41:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126061, encodeId=63b0126061ee, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Sep 14 08:12:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=124669, encodeId=750412466912, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Tue Sep 13 11:00:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=124671, encodeId=c09b1246e15e, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Tue Sep 13 11:00:00 CST 2016, time=2016-09-13, status=1, ipAttribution=)]
    2016-09-14 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

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    2016-09-14 1dd8a7c5m95(暂无匿称)

    学习了，赞一个！！！

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1945416, encodeId=27721945416b4, content=<a href='/topic/show?id=96b89544950' target=_blank style='color:#2F92EE;'>#配方奶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95449, encryptionId=96b89544950, topicName=配方奶)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aae2431, createdName=venlin, createdTime=Fri Dec 30 04:50:00 CST 2016, time=2016-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126234, encodeId=f105126234d8, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Sep 14 09:41:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126061, encodeId=63b0126061ee, content=学习了，赞一个！！！, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Wed Sep 14 08:12:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=124669, encodeId=750412466912, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Tue Sep 13 11:00:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=124671, encodeId=c09b1246e15e, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Tue Sep 13 11:00:00 CST 2016, time=2016-09-13, status=1, ipAttribution=)]
    2016-09-13 doctorJiangchao

    继续学习

    0

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    2016-09-13 doctorJiangchao

    继续学习

    0

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