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Sci Rep:不同程度肥胖患者根治性前列腺切除术后生化复发的风险因子差异分析

2020-07-22 AlexYang MedSci原创

最近,有研究人员评估了通过肥胖程度分层的患者中,在根治性前列腺切除术后生化复发(BCR)风险因子的差异情况,并关注了使用的手术方法。

最近,有研究人员评估了通过肥胖程度分层的患者中,在根治性前列腺切除术后生化复发(BCR)风险因子的差异情况,并关注了使用的手术方法。

研究包括了来自2个医疗中心的经历了根治性前列腺切除术的3099名患者,时间为2008年到2018年。研究人员将这些患者根据身体质量指数(BMI)进行分组:正常组、超重组和肥胖组。研究发现,肥胖组和超重组中分别包括378名(12.2%)患者和1815名(58.6%)患者。同时,1324名患者经历了耻骨后前列腺切除(RRP),1775名患者经历了机器人辅助的腹腔镜前列腺切除术(RALP)。多变量分析表明在超重组和肥胖组中,经历了RALP的患者比经历了RRP的患者具有显著更低的无生存BCR(风险比分别为0.75(95%CI 0.59-0.95, p=0.01和0.55(95%CI 0.33-0.90, p=0.02)。

最后,研究人员指出,肥胖的程度与无生存BCR物直接相关性。在超重组和肥胖组中,机器人前列腺切除术的无生存BCR要比开放式前列腺切除更好。

原始出处:

Jungyo Suh, Sangjun Yoo, Juhyun Park et al. Differences in risk factors for biochemical recurrence after radical prostatectomy stratified by the degree of obesity: Focused on surgical methods. Sci Rep. 23 June 2020

 

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    2020-07-25 ms1000002126003138

    0

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    2020-07-24 jeanqiuqiu
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