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脑肿瘤发展的潜在生物标志物-维生素E

2016-05-25 佚名 生物360

瑞典Ume大学和挪威癌症登记处的研究人员研究了可能的脑肿瘤产生的原因。这一研究结果发表在《Oncotarget》上,结果表明最终会发展为脑肿瘤的人与那些比较健康的人相比,某些分子的表达,也就是所说的代谢产物有一定的差异。发现维生素E的差异最大。“我们知道,与健康相关的生活方式因素,如吸烟和喝酒与脑肿瘤是不相关的。所以找到维生素E和脑肿瘤之间可能的联系信号是相当有趣的,我们也会更仔细地进行研究,”放

瑞典Ume大学和挪威癌症登记处的研究人员研究了可能的脑肿瘤产生的原因。这一研究结果发表在《Oncotarget》上,结果表明最终会发展为脑肿瘤的人与那些比较健康的人相比,某些分子的表达,也就是所说的代谢产物有一定的差异。发现维生素E的差异最大。



“我们知道,与健康相关的生活方式因素,如吸烟和喝酒与脑肿瘤是不相关的。所以找到维生素E和脑肿瘤之间可能的联系信号是相当有趣的,我们也会更仔细地进行研究,”放射科学系的研究人员和文章的共同作者Beatrice Melin说,“但我们必须指出的是,这只是初步的结果,还需要对大量的患者进行进一步研究,以验证维生素E和脑肿瘤之间的联系。


UME?大学放射科学与化学系的一组研究人员,在Beatrice Melin 和Henrik Antti的带领下,用仅有的生物材料库中来自于脑肿瘤患者的血清进行了这项研究,在诊断前做了二十年的工作。研究者们研究了那些后来发展为脑肿瘤的人和对照组的代谢产物之间的差异。


“其他的研究也表明了来自于维生素E对健康产生不利影响的迹象,因此我们的研究结果与当前其他类型的关于肿瘤的研究结果是一致的,”化学研究室研究员、研究的合著者健康说。”我们一定会仔细解释我们的研究结果,现在我们将继续进行这项研究,以探讨是否遗传学在所观察到的生物标志物模式中也发挥着作用。”


代谢组学用于未来疾病潜在变化因素的研究,如脑肿瘤,是一个特别的领域,促进医学的发展。



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    2016-10-14 ylzr123

    赞一个!好文章拜读了,认真学习了。

    0

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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419835, encodeId=7e2b141983554, content=<a href='/topic/show?id=60f8e908078' target=_blank style='color:#2F92EE;'>#维生素E#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79080, encryptionId=60f8e908078, topicName=维生素E)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6fe53536268, createdName=marongnuan, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560556, encodeId=af02156055640, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, 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    2016-09-30 1e10c84am36(暂无匿称)

    拜读,好文

    0

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createdTime=Wed Sep 28 02:31:20 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1840892, encodeId=cfe61840892d7, content=<a href='/topic/show?id=18bf61953d3' target=_blank style='color:#2F92EE;'>#标志物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61953, encryptionId=18bf61953d3, topicName=标志物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Sat Oct 01 17:53:00 CST 2016, time=2016-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87728, encodeId=48428e72858, content=学习了!有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Tue May 31 09:00:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87729, encodeId=2c638e72964, content=学习了!有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Tue May 31 09:00:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417997, encodeId=e3b5141e99743, content=<a href='/topic/show?id=6ba485016cd' target=_blank style='color:#2F92EE;'>#脑肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85016, encryptionId=6ba485016cd, topicName=脑肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76f03326658, createdName=839640779, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419835, encodeId=7e2b141983554, content=<a href='/topic/show?id=60f8e908078' target=_blank style='color:#2F92EE;'>#维生素E#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79080, encryptionId=60f8e908078, topicName=维生素E)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6fe53536268, createdName=marongnuan, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560556, encodeId=af02156055640, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=)]
    2016-09-28 goddess 328

    新概念!学习!

    0

  5. 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2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87729, encodeId=2c638e72964, content=学习了!有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Tue May 31 09:00:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417997, encodeId=e3b5141e99743, content=<a href='/topic/show?id=6ba485016cd' target=_blank style='color:#2F92EE;'>#脑肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85016, encryptionId=6ba485016cd, topicName=脑肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76f03326658, createdName=839640779, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419835, encodeId=7e2b141983554, content=<a href='/topic/show?id=60f8e908078' target=_blank style='color:#2F92EE;'>#维生素E#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79080, encryptionId=60f8e908078, topicName=维生素E)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6fe53536268, createdName=marongnuan, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560556, encodeId=af02156055640, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1969123, encodeId=fb8d1969123de, content=<a href='/topic/show?id=44b482858c1' target=_blank style='color:#2F92EE;'>#肿瘤发展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82858, encryptionId=44b482858c1, topicName=肿瘤发展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Thu Apr 06 21:53:00 CST 2017, time=2017-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148206, encodeId=6577148206c6, content=赞一个!好文章拜读了,认真学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, 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2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87729, encodeId=2c638e72964, content=学习了!有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Tue May 31 09:00:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417997, encodeId=e3b5141e99743, content=<a href='/topic/show?id=6ba485016cd' target=_blank style='color:#2F92EE;'>#脑肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85016, encryptionId=6ba485016cd, topicName=脑肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76f03326658, createdName=839640779, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419835, encodeId=7e2b141983554, content=<a href='/topic/show?id=60f8e908078' target=_blank style='color:#2F92EE;'>#维生素E#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79080, encryptionId=60f8e908078, topicName=维生素E)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6fe53536268, createdName=marongnuan, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560556, encodeId=af02156055640, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=)]
    2016-05-31 lsblb

    学习了!有道理

    0

  7. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419835, encodeId=7e2b141983554, content=<a href='/topic/show?id=60f8e908078' target=_blank style='color:#2F92EE;'>#维生素E#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79080, encryptionId=60f8e908078, topicName=维生素E)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6fe53536268, createdName=marongnuan, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560556, encodeId=af02156055640, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=)]
    2016-05-31 lsblb

    学习了!有道理

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1969123, encodeId=fb8d1969123de, content=<a href='/topic/show?id=44b482858c1' target=_blank style='color:#2F92EE;'>#肿瘤发展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82858, encryptionId=44b482858c1, topicName=肿瘤发展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Thu Apr 06 21:53:00 CST 2017, time=2017-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148206, encodeId=6577148206c6, content=赞一个!好文章拜读了,认真学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri Oct 14 14:11:45 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=138089, encodeId=5f9e138089c6, content=拜读,好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Sep 30 14:40:57 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=136777, encodeId=7298136e7749, content=新概念!学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55a51936147, createdName=goddess 328, createdTime=Wed Sep 28 02:31:20 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1840892, encodeId=cfe61840892d7, content=<a href='/topic/show?id=18bf61953d3' target=_blank style='color:#2F92EE;'>#标志物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61953, encryptionId=18bf61953d3, topicName=标志物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Sat Oct 01 17:53:00 CST 2016, time=2016-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87728, encodeId=48428e72858, content=学习了!有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Tue May 31 09:00:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87729, encodeId=2c638e72964, content=学习了!有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Tue May 31 09:00:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417997, encodeId=e3b5141e99743, content=<a href='/topic/show?id=6ba485016cd' target=_blank style='color:#2F92EE;'>#脑肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85016, encryptionId=6ba485016cd, topicName=脑肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76f03326658, createdName=839640779, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419835, encodeId=7e2b141983554, content=<a href='/topic/show?id=60f8e908078' target=_blank style='color:#2F92EE;'>#维生素E#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79080, encryptionId=60f8e908078, topicName=维生素E)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6fe53536268, createdName=marongnuan, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560556, encodeId=af02156055640, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=)]
  9. [GetPortalCommentsPageByObjectIdResponse(id=1969123, encodeId=fb8d1969123de, content=<a href='/topic/show?id=44b482858c1' target=_blank style='color:#2F92EE;'>#肿瘤发展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82858, encryptionId=44b482858c1, topicName=肿瘤发展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Thu Apr 06 21:53:00 CST 2017, time=2017-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148206, encodeId=6577148206c6, content=赞一个!好文章拜读了,认真学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri Oct 14 14:11:45 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=138089, encodeId=5f9e138089c6, content=拜读,好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Sep 30 14:40:57 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=136777, encodeId=7298136e7749, content=新概念!学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55a51936147, createdName=goddess 328, createdTime=Wed Sep 28 02:31:20 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1840892, encodeId=cfe61840892d7, content=<a href='/topic/show?id=18bf61953d3' target=_blank style='color:#2F92EE;'>#标志物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61953, encryptionId=18bf61953d3, topicName=标志物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Sat Oct 01 17:53:00 CST 2016, time=2016-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87728, encodeId=48428e72858, content=学习了!有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Tue May 31 09:00:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87729, encodeId=2c638e72964, content=学习了!有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Tue May 31 09:00:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417997, encodeId=e3b5141e99743, content=<a href='/topic/show?id=6ba485016cd' target=_blank style='color:#2F92EE;'>#脑肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85016, encryptionId=6ba485016cd, topicName=脑肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76f03326658, createdName=839640779, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419835, encodeId=7e2b141983554, content=<a href='/topic/show?id=60f8e908078' target=_blank style='color:#2F92EE;'>#维生素E#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79080, encryptionId=60f8e908078, topicName=维生素E)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6fe53536268, createdName=marongnuan, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560556, encodeId=af02156055640, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=)]
  10. [GetPortalCommentsPageByObjectIdResponse(id=1969123, encodeId=fb8d1969123de, content=<a href='/topic/show?id=44b482858c1' target=_blank style='color:#2F92EE;'>#肿瘤发展#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82858, encryptionId=44b482858c1, topicName=肿瘤发展)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Thu Apr 06 21:53:00 CST 2017, time=2017-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148206, encodeId=6577148206c6, content=赞一个!好文章拜读了,认真学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri Oct 14 14:11:45 CST 2016, time=2016-10-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=138089, encodeId=5f9e138089c6, content=拜读,好文, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Sep 30 14:40:57 CST 2016, time=2016-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=136777, encodeId=7298136e7749, content=新概念!学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55a51936147, createdName=goddess 328, createdTime=Wed Sep 28 02:31:20 CST 2016, time=2016-09-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1840892, encodeId=cfe61840892d7, content=<a href='/topic/show?id=18bf61953d3' target=_blank style='color:#2F92EE;'>#标志物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61953, encryptionId=18bf61953d3, topicName=标志物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Sat Oct 01 17:53:00 CST 2016, time=2016-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87728, encodeId=48428e72858, content=学习了!有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Tue May 31 09:00:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87729, encodeId=2c638e72964, content=学习了!有道理, beContent=null, objectType=article, channel=null, level=null, likeNumber=198, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f9f21613855, createdName=lsblb, createdTime=Tue May 31 09:00:00 CST 2016, time=2016-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1417997, encodeId=e3b5141e99743, content=<a href='/topic/show?id=6ba485016cd' target=_blank style='color:#2F92EE;'>#脑肿瘤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=85016, encryptionId=6ba485016cd, topicName=脑肿瘤)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=76f03326658, createdName=839640779, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1419835, encodeId=7e2b141983554, content=<a href='/topic/show?id=60f8e908078' target=_blank style='color:#2F92EE;'>#维生素E#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79080, encryptionId=60f8e908078, topicName=维生素E)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6fe53536268, createdName=marongnuan, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560556, encodeId=af02156055640, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Fri May 27 05:53:00 CST 2016, time=2016-05-27, status=1, ipAttribution=)]
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