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EMAS发表VitD与绝经后健康的声明

2012-02-15 刘玉华 中国医学论坛报

  最近,欧洲男女更年期协会(EMAS)就维生素D(VD)与绝经后健康问题发表了立场声明,该声明发表在《欧洲更年期杂志》【Maturitas 71 (2012) 83– 88】。   该声明强调:    VD充足时不必使用强化食品;   夏天中午有规律地在太阳下照晒(不使用防晒霜)15分钟,每周3~4次,可产生健康的血清25(OH)D水平;   每日

  最近,欧洲男女更年期协会(EMAS)就维生素D(VD)与绝经后健康问题发表了立场声明,该声明发表在《欧洲更年期杂志》【Maturitas 71 (2012) 83– 88】。

  该声明强调:

   VD充足时不必使用强化食品;

  夏天中午有规律地在太阳下照晒(不使用防晒霜)15分钟,每周3~4次,可产生健康的血清25(OH)D水平;

  每日推荐的VD供给量从600IU/d(国际单位/天)增至800IU/d(≥71岁的老人);

  可采用VD2或VD3进行补充,根据使用剂量及是否存在合并症如肾病等情况进行监测。

  其他结果

  VD的天然来源主要是通过阳光照射刺激皮肤合成,饮食来源较少,如富含脂肪的鱼、蛋和牛奶等动物性食物为主的饮食。

  通过测定血清中25-羟基维生素D [25(OH)D]的浓度可确定体内 VD状态。25(OH)D理想的血清浓度范围是30~90(ng/mL)【75–225(nmol/L)】,尽管目前国际上尚未达成共识。

  25(OH)D血清浓度随季节(冬季较低)、纬度、海拔高度、空气污染和皮肤色素沉着、防晒霜的使用及衣物遮盖而波动。

  出现低血清25(OH)D浓度的危险因素包括:肥胖,吸收不良综合征,药物使用(如抗惊厥剂,抗逆转录病毒药物),皮肤老化,较少在太阳下照晒及居住于养老院。

  背景及方法

  VD缺乏不仅与骨质疏松症相关,还与心血管疾病、糖尿病、癌症、感染和神经变性疾病相关。尽管已有强有力的证据显示 VD对骨骼有影响,但 VD对非骨骼方面转归的影响还缺乏大型的前瞻性研究结果。根据文献回顾和专家意见共识,EMAS专家组对 VD在绝经妇女中的作用作了上述立场声明。

   声明全文链接:EMAS position statement: Vitamin D and postmenopausal health

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1256963, encodeId=a6e012569632a, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Fri Feb 17 13:21:00 CST 2012, time=2012-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1317177, encodeId=8dfc131e17790, content=<a href='/topic/show?id=74916e0414' target=_blank style='color:#2F92EE;'>#EMA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6704, encryptionId=74916e0414, topicName=EMA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Fri Feb 17 13:21:00 CST 2012, time=2012-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631463, encodeId=f3e0163146361, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Fri Feb 17 13:21:00 CST 2012, time=2012-02-17, status=1, ipAttribution=)]
    2012-02-17 fengyi812
  3. [GetPortalCommentsPageByObjectIdResponse(id=1256963, encodeId=a6e012569632a, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Fri Feb 17 13:21:00 CST 2012, time=2012-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1317177, encodeId=8dfc131e17790, content=<a href='/topic/show?id=74916e0414' target=_blank style='color:#2F92EE;'>#EMA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6704, encryptionId=74916e0414, topicName=EMA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a35a460, createdName=fengyi812, createdTime=Fri Feb 17 13:21:00 CST 2012, time=2012-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631463, encodeId=f3e0163146361, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Fri Feb 17 13:21:00 CST 2012, time=2012-02-17, status=1, ipAttribution=)]
    2012-02-17 zxxiang
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